IVJun 23, 2022
Weighted Concordance Index Loss-based Multimodal Survival Modeling for Radiation Encephalopathy Assessment in Nasopharyngeal Carcinoma RadiotherapyJiansheng Fang, Anwei Li, Pu-Yun OuYang et al.
Radiation encephalopathy (REP) is the most common complication for nasopharyngeal carcinoma (NPC) radiotherapy. It is highly desirable to assist clinicians in optimizing the NPC radiotherapy regimen to reduce radiotherapy-induced temporal lobe injury (RTLI) according to the probability of REP onset. To the best of our knowledge, it is the first exploration of predicting radiotherapy-induced REP by jointly exploiting image and non-image data in NPC radiotherapy regimen. We cast REP prediction as a survival analysis task and evaluate the predictive accuracy in terms of the concordance index (CI). We design a deep multimodal survival network (MSN) with two feature extractors to learn discriminative features from multimodal data. One feature extractor imposes feature selection on non-image data, and the other learns visual features from images. Because the priorly balanced CI (BCI) loss function directly maximizing the CI is sensitive to uneven sampling per batch. Hence, we propose a novel weighted CI (WCI) loss function to leverage all REP samples effectively by assigning their different weights with a dual average operation. We further introduce a temperature hyper-parameter for our WCI to sharpen the risk difference of sample pairs to help model convergence. We extensively evaluate our WCI on a private dataset to demonstrate its favourability against its counterparts. The experimental results also show multimodal data of NPC radiotherapy can bring more gains for REP risk prediction.
84.4ROMay 12
OrbiSim: World Models as Differentiable Physics Engines for Embodied IntelligenceJiajian Li, Jingyuan Huang, Junru Gong et al.
We present OrbiSim, a novel robotic simulation paradigm that redefines world models as a fully differentiable physics engine for embodied intelligence. Unlike prior world models that focus on unconstrained imagination in latent or visual domains, OrbiSim establishes a unified, physically-grounded pathway that bridges structured scene assets, neural dynamics, and downstream reinforcement learning. By enabling end-to-end differentiability throughout the entire simulation loop -- spanning from explicit state transitions to visual observation generation -- OrbiSim supports tasks traditionally intractable for classical simulators, such as differentiable contact modeling, gradient-based policy optimization under sparse rewards, and intuitive physical inference. Empirical results demonstrate that OrbiSim significantly outperforms state-of-the-art world models in both predictive fidelity and control performance. Furthermore, its consistent responsiveness to asset configurations and physical parameters suggests its potential as a differentiable tool for enhancing robot simulation and policy training.
LGMay 10, 2025
Video-Enhanced Offline Reinforcement Learning: A Model-Based ApproachMinting Pan, Yitao Zheng, Jiajian Li et al.
Offline reinforcement learning (RL) enables policy optimization using static datasets, avoiding the risks and costs of extensive real-world exploration. However, it struggles with suboptimal offline behaviors and inaccurate value estimation due to the lack of environmental interaction. We present Video-Enhanced Offline RL (VeoRL), a model-based method that constructs an interactive world model from diverse, unlabeled video data readily available online. Leveraging model-based behavior guidance, our approach transfers commonsense knowledge of control policy and physical dynamics from natural videos to the RL agent within the target domain. VeoRL achieves substantial performance gains (over 100% in some cases) across visual control tasks in robotic manipulation, autonomous driving, and open-world video games.