Zhixuan Wang

Xuefeng Wei, Zhixuan Wang, Xuan Zhou et al.

We introduce CARTBENCH, a museum-grounded benchmark for evaluating vision-language models (VLMs) on Chinese artworks beyond short-form recognition and QA. CARTBENCH comprises four subtasks: CURATORQA for evidence-grounded recognition and reasoning, CATALOGCAPTION for structured four-section expert-style appreciation, REINTERPRET for defensible reinterpretation with expert ratings, and CONNOISSEURPAIRS for diagnostic authenticity discrimination under visually similar confounds. CARTBENCH is built by aligning image-bearing Palace Museum objects from Wikidata with authoritative catalog pages, spanning five art categories across multiple dynasties. Across nine representative VLMs, we find that high overall CURATORQA accuracy can mask sharp drops on hard evidence linking and style-to-period inference; long-form appreciation remains far from expert references; and authenticity-oriented diagnostic discrimination stays near chance, underscoring the difficulty of connoisseur-level reasoning for current models.

Zhixuan Wang

Epilepsy is a prevalent neurological disease with millions of patients worldwide. Many patients have turned to alternative medicine due to the limited efficacy and side effects of conventional antiepileptic drugs. In this study, we developed a computational approach to optimize herbal epilepsy treatment through AI-driven analysis of global natural products and statistically validated randomized controlled trials (RCTs). Our intelligent prescription system combines machine learning (ML) algorithms for herb-efficacy characterization, Bayesian optimization for personalized dosing, and meta-analysis of RCTs for evidence-based recommendations. The system analyzed 1,872 natural compounds from traditional Chinese medicine (TCM), Ayurveda, and ethnopharmacological databases, integrating their bioactive properties with clinical outcomes from 48 RCTs covering 48 epilepsy conditions (n=5,216). Using LASSO regression and SHAP value analysis, we identified 17 high-efficacy herbs (e.g., Gastrodia elata [using é for accented characters], Withania somnifera), showing significant seizure reduction (p$<$0.01, Cohen's d=0.89) with statistical significance confirmed by multiple testing (p$<$0.001). A randomized double-blind validation trial (n=120) demonstrated 28.5\% greater seizure frequency reduction with AI-optimized herbal prescriptions compared to conventional protocols (95\% CI: 18.7-37.3\%, p=0.003).

Xingrui Gu, Zhixuan Wang, Irisa Jin et al.

This research presents a novel multimodal data fusion methodology for pain behavior recognition, integrating statistical correlation analysis with human-centered insights. Our approach introduces two key innovations: 1) integrating data-driven statistical relevance weights into the fusion strategy to effectively utilize complementary information from heterogeneous modalities, and 2) incorporating human-centric movement characteristics into multimodal representation learning for detailed modeling of pain behaviors. Validated across various deep learning architectures, our method demonstrates superior performance and broad applicability. We propose a customizable framework that aligns each modality with a suitable classifier based on statistical significance, advancing personalized and effective multimodal fusion. Furthermore, our methodology provides explainable analysis of multimodal data, contributing to interpretable and explainable AI in healthcare. By highlighting the importance of data diversity and modality-specific representations, we enhance traditional fusion techniques and set new standards for recognizing complex pain behaviors. Our findings have significant implications for promoting patient-centered healthcare interventions and supporting explainable clinical decision-making.

Shaoyu Pei, Renxiong Wu, Hao Zheng et al.

Skin, the primary regulator of heat exchange, relies on sweat glands for thermoregulation. Alterations in sweat gland morphology play a crucial role in various pathological conditions and clinical diagnoses. Current methods for observing sweat gland morphology are limited by their two-dimensional, in vitro, and destructive nature, underscoring the urgent need for real-time, non-invasive, quantifiable technologies. We proposed a novel three-dimensional (3D) transformer-based multi-object segmentation framework, integrating a sliding window approach, joint spatial-channel attention mechanism, and architectural heterogeneity between shallow and deep layers. Our proposed network enables precise 3D sweat gland segmentation from skin volume data captured by optical coherence tomography (OCT). For the first time, subtle variations of sweat gland 3D morphology in response to temperature changes, have been visualized and quantified. Our approach establishes a benchmark for normal sweat gland morphology and provides a real-time, non-invasive tool for quantifying 3D structural parameters. This enables the study of individual variability and pathological changes in sweat gland structure, advancing dermatological research and clinical applications, including thermoregulation and bromhidrosis treatment.