Dian Chen

Dian Chen, Han Jun Yoon, Zelin Wan et al.

Human-Machine Teaming (HMT) is revolutionizing collaboration across domains such as defense, healthcare, and autonomous systems by integrating AI-driven decision-making, trust calibration, and adaptive teaming. This survey presents a comprehensive taxonomy of HMT, analyzing theoretical models, including reinforcement learning, instance-based learning, and interdependence theory, alongside interdisciplinary methodologies. Unlike prior reviews, we examine team cognition, ethical AI, multi-modal interactions, and real-world evaluation frameworks. Key challenges include explainability, role allocation, and scalable benchmarking. We propose future research in cross-domain adaptation, trust-aware AI, and standardized testbeds. By bridging computational and social sciences, this work lays a foundation for resilient, ethical, and scalable HMT systems.

Dawood Wasif, Dian Chen, Sindhuja Madabushi et al.

Federated Learning (FL) enables collaborative model training while preserving data privacy; however, balancing privacy preservation (PP) and fairness poses significant challenges. In this paper, we present the first unified large-scale empirical study of privacy-fairness-utility trade-offs in FL, advancing toward responsible AI deployment. Specifically, we systematically compare Differential Privacy (DP), Homomorphic Encryption (HE), and Secure Multi-Party Computation (SMC) with fairness-aware optimizers including q-FedAvg, q-MAML, Ditto, evaluating their performance under IID and non-IID scenarios using benchmark (MNIST, Fashion-MNIST) and real-world datasets (Alzheimer's MRI, credit-card fraud detection). Our analysis reveals HE and SMC significantly outperform DP in achieving equitable outcomes under data skew, although at higher computational costs. Remarkably, we uncover unexpected interactions: DP mechanisms can negatively impact fairness, and fairness-aware optimizers can inadvertently reduce privacy effectiveness. We conclude with practical guidelines for designing robust FL systems that deliver equitable, privacy-preserving, and accurate outcomes.

Basil Hasan Khwaja, Dylan Chen, Guntas Toor et al.

Large language models (LLMs) have shown strong empirical performance across pharmacology and drug discovery tasks, yet the internal mechanisms by which they encode pharmacological knowledge remain poorly understood. In this work, we investigate how drug-group semantics are represented and retrieved within Llama-based biomedical language models using causal and probing-based interpretability methods. We apply activation patching to localize where drug-group information is stored across model layers and token positions, and complement this analysis with linear probes trained on token-level and sum-pooled activations. Our results demonstrate that early layers play a key role in encoding drug-group knowledge, with the strongest causal effects arising from intermediate tokens within the drug-group span rather than the final drug-group token. Linear probing further reveals that pharmacological semantics are distributed across tokens and are already present in the embedding space, with token-level probes performing near chance while sum-pooled representations achieve maximal accuracy. Together, these findings suggest that drug-group semantics in LLMs are not localized to single tokens but instead arise from distributed representations. This study provides the first systematic mechanistic analysis of pharmacological knowledge in LLMs, offering insights into how biomedical semantics are encoded in large language models.