Andrea Dunn Beltran

Xinqi Xiong, Andrea Dunn Beltran, Junmyeong Choi et al.

Accurate polyp size stratification guides surveillance decisions, with lesions larger than 5 mm typically requiring closer follow-up. However, monocular colonoscopy lacks a reliable metric reference. We present a diagnostic audit of binary polyp size classification (<=5 mm vs. >5 mm) across multiple public multi-center datasets, model families, and patient-stratified cross-validation. Across architectures and input modalities, including RGB appearance, relative depth, and photometry, model performance is moderately consistent, suggesting reliance on cues correlated with examination behavior rather than true metric scales. By providing ground-truth scale at varying granularities, we quantify the potential improvement from perfect scale information and show that current depth estimation and global calibration offer limited gains. We further demonstrate that segmentation errors under distribution shift eliminate most of this potential, with oracle scale under predicted masks recovering only baseline performance. These results highlight metric scale and mask robustness as two independent bottlenecks and provide reusable evaluation tools such as oracle scale ladders, shortcut partitions, and mask substitution for auditing future polyp sizing pipelines. Our code is publicly accessible at https://github.com/anaxqx/polyp-sizing-audit.

Xinqi Xiong, Andrea Dunn Beltran, Jun Myeong Choi et al.

Accurate depth estimation enhances endoscopy navigation and diagnostics, but obtaining ground-truth depth in clinical settings is challenging. Synthetic datasets are often used for training, yet the domain gap limits generalization to real data. We propose a novel image-to-image translation framework that preserves structure while generating realistic textures from clinical data. Our key innovation integrates Stable Diffusion with ControlNet, conditioned on a latent representation extracted from a Per-Pixel Shading (PPS) map. PPS captures surface lighting effects, providing a stronger structural constraint than depth maps. Experiments show our approach produces more realistic translations and improves depth estimation over GAN-based MI-CycleGAN. Our code is publicly accessible at https://github.com/anaxqx/PPS-Ctrl.

Andrea Dunn Beltran, Daniel Rho, Aarav Mehta et al.

Bronchoscopic navigation relies on registering endoscopic video to a preoperative CT scan, but respiratory motion deforms the airway by 5-20 mm, creating CT-to-body divergence that limits localization accuracy. In practice, this is mitigated through breath-hold protocols, which attempt to match the intraoperative anatomy to a static CT, but are difficult to reproduce and disrupt clinical workflow. We propose to eliminate the need for breath-hold protocols by leveraging patient-specific respiratory modeling. Paired inhale-exhale CT scans, already acquired for planning, implicitly define the patient-specific deformation space of the breathing airway. By registering these scans, we reduce respiratory motion to a single scalar breathing phase per frame, constraining all reconstructions to anatomically observed configurations. We embed this representation within a mesh-anchored Gaussian splatting framework, where a lightweight estimator infers breathing phase directly from endoscopic RGB, enabling continuous, deformation-aware reconstruction throughout the respiratory cycle without breath-holds or external sensing. To enable quantitative evaluation, we introduce RESPIRE, a physically grounded bronchoscopy simulation pipeline with per-frame ground truth for geometry, pose, breathing phase, and deformation. Experiments on RESPIRE show that our approach achieves geometrically faithful reconstruction, over 20x faster training, and 1.22 mm target localization accuracy (within the 3mm clinically relevant tolerances) outperforming unconstrained single-CT baselines. Please check out our website for additional visuals: https://asdunnbe.github.io/RESPIRE/

Andrea Dunn Beltran, Daniel Rho, Marc Niethammer et al.

Simultaneous Localization and Mapping (SLAM) systems typically assume static, distant illumination; however, many real-world scenarios, such as endoscopy, subterranean robotics, and search & rescue in collapsed environments, require agents to operate with a co-located light and camera in the absence of external lighting. In such cases, dynamic near-field lighting introduces strong, view-dependent shading that significantly degrades SLAM performance. We introduce Near-Field Lighting Bundle Adjustment Loss (NFL-BA) which explicitly models near-field lighting as a part of Bundle Adjustment loss and enables better performance for scenes captured with dynamic lighting. NFL-BA can be integrated into neural rendering-based SLAM systems with implicit or explicit scene representations. Our evaluations mainly focus on endoscopy procedure where SLAM can enable autonomous navigation, guidance to unsurveyed regions, blindspot detections, and 3D visualizations, which can significantly improve patient outcomes and endoscopy experience for both physicians and patients. Replacing Photometric Bundle Adjustment loss of SLAM systems with NFL-BA leads to significant improvement in camera tracking, 37% for MonoGS and 14% for EndoGS, and leads to state-of-the-art camera tracking and mapping performance on the C3VD colonoscopy dataset. Further evaluation on indoor scenes captured with phone camera with flashlight turned on, also demonstrate significant improvement in SLAM performance due to NFL-BA. See results at https://asdunnbe.github.io/NFL-BA/

Noah Frahm, Dongxu Zhao, Andrea Dunn Beltran et al.

Next Best View (NBV) algorithms aim to maximize 3D scene acquisition quality using minimal resources, e.g. number of acquisitions, time taken, or distance traversed. Prior methods often rely on coverage maximization as a proxy for reconstruction quality, but for complex scenes with occlusions and finer details, this is not always sufficient and leads to poor reconstructions. Our key insight is to train an acquisition policy that directly optimizes for reconstruction quality rather than just coverage. To achieve this, we introduce the View Introspection Network (VIN): a lightweight neural network that predicts the Relative Reconstruction Improvement (RRI) of a potential next viewpoint without making any new acquisitions. We use this network to power a simple, yet effective, sequential samplingbased greedy NBV policy. Our approach, VIN-NBV, generalizes to unseen object categories, operates without prior scene knowledge, is adaptable to resource constraints, and can handle occlusions. We show that our RRI fitness criterion leads to a ~30% gain in reconstruction quality over a coverage-based criterion using the same greedy strategy. Furthermore, VIN-NBV also outperforms deep reinforcement learning methods, Scan-RL and GenNBV, by ~40%.