Markus Wolfien

Kristian Schultz, Saptarshi Bej, Waldemar Hahn et al.

Data is commonly stored in tabular format. Several fields of research are prone to small imbalanced tabular data. Supervised Machine Learning on such data is often difficult due to class imbalance. Synthetic data generation, i.e., oversampling, is a common remedy used to improve classifier performance. State-of-the-art linear interpolation approaches, such as LoRAS and ProWRAS can be used to generate synthetic samples from the convex space of the minority class to improve classifier performance in such cases. Deep generative networks are common deep learning approaches for synthetic sample generation, widely used for synthetic image generation. However, their scope on synthetic tabular data generation in the context of imbalanced classification is not adequately explored. In this article, we show that existing deep generative models perform poorly compared to linear interpolation based approaches for imbalanced classification problems on smaller tabular datasets. To overcome this, we propose a deep generative model, ConvGeN that combines the idea of convex space learning with deep generative models. ConvGeN learns the coefficients for the convex combinations of the minority class samples, such that the synthetic data is distinct enough from the majority class. Our benchmarking experiments demonstrate that our proposed model ConvGeN improves imbalanced classification on such small datasets, as compared to existing deep generative models, while being at-par with the existing linear interpolation approaches. Moreover, we discuss how our model can be used for synthetic tabular data generation in general, even outside the scope of data imbalance and thus, improves the overall applicability of convex space learning.

Waldemar Hahn, Jan-Niklas Eckardt, Christoph Röllig et al.

The generation of synthetic clinical trial data offers a promising approach to mitigating privacy concerns and data accessibility limitations in medical research. However, ensuring that synthetic datasets maintain high fidelity, utility, and adherence to domain-specific constraints remains a key challenge. While hyperparameter optimization (HPO) has been shown to improve generative model performance, the effectiveness of different optimization strategies for synthetic clinical data remains unclear. This study systematically evaluates four HPO strategies across eight generative models, comparing single-metric optimization against compound metric optimization approaches. Our results demonstrate that HPO consistently improves synthetic data quality, with TVAE, CTGAN, and CTAB-GAN+ achieving improvements of up to 60%, 39%, and 38%, respectively. Compound metric optimization outperformed single-metric strategies, producing more balanced and generalizable synthetic datasets. Interestingly, HPO alone is insufficient to ensure clinically valid synthetic data, as all models exhibited violations of fundamental survival constraints. Preprocessing and postprocessing played a crucial role in reducing these violations, as models lacking robust processing steps produced invalid data in up to 61% of cases. These findings underscore the necessity of integrating explicit domain knowledge alongside HPO to create high quality synthetic datasets. Our study provides actionable recommendations for improving synthetic data generation, with future research needed to refine metric selection and validate these findings on larger datasets to enhance clinical applicability.

Saptarshi Bej, Kristian Schultz, Prashant Srivastava et al.

Over 85 oversampling algorithms, mostly extensions of the SMOTE algorithm, have been built over the past two decades, to solve the problem of imbalanced datasets. However, it has been evident from previous studies that different oversampling algorithms have different degrees of efficiency with different classifiers. With numerous algorithms available, it is difficult to decide on an oversampling algorithm for a chosen classifier. Here, we overcome this problem with a multi-schematic and classifier-independent oversampling approach: ProWRAS(Proximity Weighted Random Affine Shadowsampling). ProWRAS integrates the Localized Random Affine Shadowsampling (LoRAS)algorithm and the Proximity Weighted Synthetic oversampling (ProWSyn) algorithm. By controlling the variance of the synthetic samples, as well as a proximity-weighted clustering system of the minority classdata, the ProWRAS algorithm improves performance, compared to algorithms that generate synthetic samples through modelling high dimensional convex spaces of the minority class. ProWRAS has four oversampling schemes, each of which has its unique way to model the variance of the generated data. Most importantly, the performance of ProWRAS with proper choice of oversampling schemes, is independent of the classifier used. We have benchmarked our newly developed ProWRAS algorithm against five sate-of-the-art oversampling models and four different classifiers on 20 publicly available datasets. ProWRAS outperforms other oversampling algorithms in a statistically significant way, in terms of both F1-score and Kappa-score. Moreover, we have introduced a novel measure for classifier independence I-score, and showed quantitatively that ProWRAS performs better, independent of the classifier used. In practice, ProWRAS customizes synthetic sample generation according to a classifier of choice and thereby reduces benchmarking efforts.

Saptarshi Bej, Narek Davtyan, Markus Wolfien et al.

The Synthetic Minority Oversampling TEchnique (SMOTE) is widely-used for the analysis of imbalanced datasets. It is known that SMOTE frequently over-generalizes the minority class, leading to misclassifications for the majority class, and effecting the overall balance of the model. In this article, we present an approach that overcomes this limitation of SMOTE, employing Localized Random Affine Shadowsampling (LoRAS) to oversample from an approximated data manifold of the minority class. We benchmarked our algorithm with 14 publicly available imbalanced datasets using three different Machine Learning (ML) algorithms and compared the performance of LoRAS, SMOTE and several SMOTE extensions that share the concept of using convex combinations of minority class data points for oversampling with LoRAS. We observed that LoRAS, on average generates better ML models in terms of F1-Score and Balanced accuracy. Another key observation is that while most of the extensions of SMOTE we have tested, improve the F1-Score with respect to SMOTE on an average, they compromise on the Balanced accuracy of a classification model. LoRAS on the contrary, improves both F1 Score and the Balanced accuracy thus produces better classification models. Moreover, to explain the success of the algorithm, we have constructed a mathematical framework to prove that LoRAS oversampling technique provides a better estimate for the mean of the underlying local data distribution of the minority class data space.