Sarv Priya

Joseph Kettelkamp, Ludovica Romanin, Sarv Priya et al.

We introduce an unsupervised motion-compensated image reconstruction algorithm for free-breathing and ungated 3D cardiac magnetic resonance imaging (MRI). We express the image volume corresponding to each specific motion phase as the deformation of a single static image template. The main contribution of the work is the low-rank model for the compact joint representation of the family of diffeomorphisms, parameterized by the motion phases. The diffeomorphism at a specific motion phase is obtained by integrating a parametric velocity field along a path connecting the reference template phase to the motion phase. The velocity field at different phases is represented using a low-rank model. The static template and the low-rank motion model parameters are learned directly from the k-space data in an unsupervised fashion. The more constrained motion model is observed to offer improved recovery compared to current motion-resolved and motion-compensated algorithms for free-breathing 3D cine MRI.

Qing Zou, Abdul Haseeb Ahmed, Prashant Nagpal et al.

Free-breathing cardiac MRI schemes are emerging as competitive alternatives to breath-held cine MRI protocols, enabling applicability to pediatric and other population groups that cannot hold their breath. Because the data from the slices are acquired sequentially, the cardiac/respiratory motion patterns may be different for each slice; current free-breathing approaches perform independent recovery of each slice. In addition to not being able to exploit the inter-slice redundancies, manual intervention or sophisticated post-processing methods are needed to align the images post-recovery for quantification. To overcome these challenges, we propose an unsupervised variational deep manifold learning scheme for the joint alignment and reconstruction of multislice dynamic MRI. The proposed scheme jointly learns the parameters of the deep network as well as the latent vectors for each slice, which capture the motion-induced dynamic variations, from the k-t space data of the specific subject. The variational framework minimizes the non-uniqueness in the representation, thus offering improved alignment and reconstructions.