Bjorn Stinner

Till Bretschneider, Cheng-Jin Du, Charles M. Elliott et al.

We present a computational approach for solving reaction-diffusion equations on evolving surfaces which have been obtained from cell image data. It is based on finite element spaces defined on surface triangulations extracted from time series of 3D images. A model for the transport of material between the subsequent surfaces is required where we postulate a velocity in normal direction. We apply the technique to image data obtained from a spreading neutrophil cell. By simulating FRAP experiments we investigate the impact of the evolving geometry on the recovery. We find that for idealised FRAP conditions, changes in membrane geometry, easily account for differences of $\times 10$ in recovery half-times, which shows that experimentalists must take great care when interpreting membrane photobleaching results. We also numerically solve an activator -- depleted substrate system and report on the effect of the membrane movement on the pattern evolution.

Oliver R. A. Dunbar, Kei Fong Lam, Bjorn Stinner

A diffuse interface model for surfactants in multi-phase flow with three or more fluids is derived. A system of Cahn-Hilliard equations is coupled with a Navier-Stokes system and an advection-diffusion equation for the surfactant ensuring thermodynamic consistency. By an asymptotic analysis the model can be related to a moving boundary problem in the sharp interface limit, which is derived from first principles. Results from numerical simulations support the theoretical findings. The main novelties are centred around the conditions in the triple junctions where three fluids meet. Specifically the case of local chemical equilibrium with respect to the surfactant is considered, which allows for interfacial surfactant flow through the triple junctions.

Paola Pozzi, Bjorn Stinner

We present and analyze a semi-discrete finite element scheme for a system consisting of a geometric evolution equation for a curve and a parabolic equation on the evolving curve. More precisely, curve shortening flow with a forcing term that depends on a field defined on the curve is coupled with a diffusion equation for that field. The scheme is based on ideas of \cite{D99} for the curve shortening flow and \cite{DE07} for the parabolic equation on the moving curve. Additional estimates are required in order to show convergence, most notably with respect to the length element: While in \cite{D99} an estimate of its error was sufficient we here also need to estimate the time derivative of the error which arises from the diffusion equation. Numerical simulation results support the theoretical findings.