Jiahao Huang

Zhibo Jin, Jiayu Zhang, Zhiyu Zhu et al.

In recent times, the swift evolution of adversarial attacks has captured widespread attention, particularly concerning their transferability and other performance attributes. These techniques are primarily executed at the sample level, frequently overlooking the intrinsic parameters of models. Such neglect suggests that the perturbations introduced in adversarial samples might have the potential for further reduction. Given the essence of adversarial attacks is to impair model integrity with minimal noise on original samples, exploring avenues to maximize the utility of such perturbations is imperative. Against this backdrop, we have delved into the complexities of adversarial attack algorithms, dissecting the adversarial process into two critical phases: the Directional Supervision Process (DSP) and the Directional Optimization Process (DOP). While DSP determines the direction of updates based on the current samples and model parameters, it has been observed that existing model parameters may not always be conducive to adversarial attacks. The impact of models on adversarial efficacy is often overlooked in current research, leading to the neglect of DSP. We propose that under certain conditions, fine-tuning model parameters can significantly enhance the quality of DSP. For the first time, we propose that under certain conditions, fine-tuning model parameters can significantly improve the quality of the DSP. We provide, for the first time, rigorous mathematical definitions and proofs for these conditions, and introduce multiple methods for fine-tuning model parameters within DSP. Our extensive experiments substantiate the effectiveness of the proposed P3A method. Our code is accessible at: https://anonymous.4open.science/r/P3A-A12C/

Zhibo Jin, Jiayu Zhang, Zhiyu Zhu et al.

Transferable adversarial attacks pose significant threats to deep neural networks, particularly in black-box scenarios where internal model information is inaccessible. Studying adversarial attack methods helps advance the performance of defense mechanisms and explore model vulnerabilities. These methods can uncover and exploit weaknesses in models, promoting the development of more robust architectures. However, current methods for transferable attacks often come with substantial computational costs, limiting their deployment and application, especially in edge computing scenarios. Adversarial generative models, such as Generative Adversarial Networks (GANs), are characterized by their ability to generate samples without the need for retraining after an initial training phase. GE-AdvGAN, a recent method for transferable adversarial attacks, is based on this principle. In this paper, we propose a novel general framework for gradient editing-based transferable attacks, named GE-AdvGAN+, which integrates nearly all mainstream attack methods to enhance transferability while significantly reducing computational resource consumption. Our experiments demonstrate the compatibility and effectiveness of our framework. Compared to the baseline AdvGAN, our best-performing method, GE-AdvGAN++, achieves an average ASR improvement of 47.8. Additionally, it surpasses the latest competing algorithm, GE-AdvGAN, with an average ASR increase of 5.9. The framework also exhibits enhanced computational efficiency, achieving 2217.7 FPS, outperforming traditional methods such as BIM and MI-FGSM. The implementation code for our GE-AdvGAN+ framework is available at https://github.com/GEAdvGANP

Lei Xie, Qingrun Zeng, Huajun Zhou et al.

Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion directions and fiber geometry, and existing diffusion tractography methods of CNs identification are prone to producing erroneous trajectories and missing true positive connections. To overcome the above challenge, we propose a novel CNs identification framework with anatomy-guided fiber trajectory distribution, which incorporates anatomical shape prior knowledge during the process of CNs tracing to build diffusion tensor vector fields. We introduce higher-order streamline differential equations for continuous flow field representations to directly characterize the fiber trajectory distribution of CNs from the tract-based level. The experimental results on the vivo HCP dataset and the clinical MDM dataset demonstrate that the proposed method reduces false-positive fiber production compared to competing methods and produces reconstructed CNs (i.e. CN II, CN III, CN V, and CN VII/VIII) that are judged to better correspond to the known anatomy.

Lei Xie, Jiahao Huang, Jiawei Zhang et al.

Cranial nerves (CNs) play a crucial role in various essential functions of the human brain, and mapping their pathways from diffusion MRI (dMRI) provides valuable preoperative insights into the spatial relationships between individual CNs and key tissues. However, mapping a comprehensive and detailed CN atlas is challenging because of the unique anatomical structures of each CN pair and the complexity of the skull base environment.In this work, we present what we believe to be the first study to develop a comprehensive diffusion tractography atlas for automated mapping of CN pathways in the human brain. The CN atlas is generated by fiber clustering by using the streamlines generated by multi-parametric fiber tractography for each pair of CNs. Instead of disposable clustering, we explore a new strategy of multi-stage fiber clustering for multiple analysis of approximately 1,000,000 streamlines generated from the 50 subjects from the Human Connectome Project (HCP). Quantitative and visual experiments demonstrate that our CN atlas achieves high spatial correspondence with expert manual annotations on multiple acquisition sites, including the HCP dataset, the Multi-shell Diffusion MRI (MDM) dataset and two clinical cases of pituitary adenoma patients. The proposed CN atlas can automatically identify 8 fiber bundles associated with 5 pairs of CNs, including the optic nerve CN II, oculomotor nerve CN III, trigeminal nerve CN V and facial-vestibulocochlear nerve CN VII/VIII, and its robustness is demonstrated experimentally. This work contributes to the field of diffusion imaging by facilitating more efficient and automated mapping the pathways of multiple pairs of CNs, thereby enhancing the analysis and understanding of complex brain structures through visualization of their spatial relationships with nearby anatomy.

Lei Xie, Huajun Zhou, Junxiong Huang et al.

The segmentation of cranial nerves (CNs) tract provides a valuable quantitative tool for the analysis of the morphology and trajectory of individual CNs. Multimodal CNs tract segmentation networks, e.g., CNTSeg, which combine structural Magnetic Resonance Imaging (MRI) and diffusion MRI, have achieved promising segmentation performance. However, it is laborious or even infeasible to collect complete multimodal data in clinical practice due to limitations in equipment, user privacy, and working conditions. In this work, we propose a novel arbitrary-modal fusion network for volumetric CNs tract segmentation, called CNTSeg-v2, which trains one model to handle different combinations of available modalities. Instead of directly combining all the modalities, we select T1-weighted (T1w) images as the primary modality due to its simplicity in data acquisition and contribution most to the results, which supervises the information selection of other auxiliary modalities. Our model encompasses an Arbitrary-Modal Collaboration Module (ACM) designed to effectively extract informative features from other auxiliary modalities, guided by the supervision of T1w images. Meanwhile, we construct a Deep Distance-guided Multi-stage (DDM) decoder to correct small errors and discontinuities through signed distance maps to improve segmentation accuracy. We evaluate our CNTSeg-v2 on the Human Connectome Project (HCP) dataset and the clinical Multi-shell Diffusion MRI (MDM) dataset. Extensive experimental results show that our CNTSeg-v2 achieves state-of-the-art segmentation performance, outperforming all competing methods.