Barbara Oakley

Anthony Zador, Jean-Marc Fellous, Terrence Sejnowski et al. · uw

Neuroscience and Artificial Intelligence (AI) have made impressive progress in recent years but remain only loosely interconnected. Based on a workshop convened by the National Science Foundation in August 2025, we identify three fundamental capability gaps in current AI: the inability to interact with the physical world, inadequate learning that produces brittle systems, and unsustainable energy and data inefficiency. We describe the neuroscience principles that address each: co-design of body and controller, prediction through interaction, multi-scale learning with neuromodulatory control, hierarchical distributed architectures, and sparse event-driven computation. We present a research roadmap organized around these principles at near, mid, and long-term horizons. We argue that realizing this program requires a new generation of researchers trained across the boundary between neuroscience and engineering, and describe the institutional conditions: interdisciplinary training, hardware access, community standards, and ethics, needed to support them. We conclude that NeuroAI, neuroscience-informed artificial intelligence, has the potential to overcome limitations of current AI while deepening our understanding of biological neural computation.

Barbara Oakley, Michael Johnston, Ken-Zen Chen et al.

In the age of generative AI and ubiquitous digital tools, human cognition faces a structural paradox: as external aids become more capable, internal memory systems risk atrophy. Drawing on neuroscience and cognitive psychology, this paper examines how heavy reliance on AI systems and discovery-based pedagogies may impair the consolidation of declarative and procedural memory -- systems essential for expertise, critical thinking, and long-term retention. We review how tools like ChatGPT and calculators can short-circuit the retrieval, error correction, and schema-building processes necessary for robust neural encoding. Notably, we highlight striking parallels between deep learning phenomena such as "grokking" and the neuroscience of overlearning and intuition. Empirical studies are discussed showing how premature reliance on AI during learning inhibits proceduralization and intuitive mastery. We argue that effective human-AI interaction depends on strong internal models -- biological "schemata" and neural manifolds -- that enable users to evaluate, refine, and guide AI output. The paper concludes with policy implications for education and workforce training in the age of large language models.