Bradley Green

Tao Tu, Shekoofeh Azizi, Danny Driess et al.

Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can potentially enable impactful applications ranging from scientific discovery to care delivery. To enable the development of these models, we first curate MultiMedBench, a new multimodal biomedical benchmark. MultiMedBench encompasses 14 diverse tasks such as medical question answering, mammography and dermatology image interpretation, radiology report generation and summarization, and genomic variant calling. We then introduce Med-PaLM Multimodal (Med-PaLM M), our proof of concept for a generalist biomedical AI system. Med-PaLM M is a large multimodal generative model that flexibly encodes and interprets biomedical data including clinical language, imaging, and genomics with the same set of model weights. Med-PaLM M reaches performance competitive with or exceeding the state of the art on all MultiMedBench tasks, often surpassing specialist models by a wide margin. We also report examples of zero-shot generalization to novel medical concepts and tasks, positive transfer learning across tasks, and emergent zero-shot medical reasoning. To further probe the capabilities and limitations of Med-PaLM M, we conduct a radiologist evaluation of model-generated (and human) chest X-ray reports and observe encouraging performance across model scales. In a side-by-side ranking on 246 retrospective chest X-rays, clinicians express a pairwise preference for Med-PaLM M reports over those produced by radiologists in up to 40.50% of cases, suggesting potential clinical utility. While considerable work is needed to validate these models in real-world use cases, our results represent a milestone towards the development of generalist biomedical AI systems.

Inkyu Shin, Dahun Kim, Qihang Yu et al.

Video Panoptic Segmentation (VPS) aims to achieve comprehensive pixel-level scene understanding by segmenting all pixels and associating objects in a video. Current solutions can be categorized into online and near-online approaches. Evolving over the time, each category has its own specialized designs, making it nontrivial to adapt models between different categories. To alleviate the discrepancy, in this work, we propose a unified approach for online and near-online VPS. The meta architecture of the proposed Video-kMaX consists of two components: within clip segmenter (for clip-level segmentation) and cross-clip associater (for association beyond clips). We propose clip-kMaX (clip k-means mask transformer) and HiLA-MB (Hierarchical Location-Aware Memory Buffer) to instantiate the segmenter and associater, respectively. Our general formulation includes the online scenario as a special case by adopting clip length of one. Without bells and whistles, Video-kMaX sets a new state-of-the-art on KITTI-STEP and VIPSeg for video panoptic segmentation, and VSPW for video semantic segmentation. Code will be made publicly available.

Raviteja Vemulapalli, Warren Richard Morningstar, Philip Andrew Mansfield et al.

Dual encoding models that encode a pair of inputs are widely used for representation learning. Many approaches train dual encoding models by maximizing agreement between pairs of encodings on centralized training data. However, in many scenarios, datasets are inherently decentralized across many clients (user devices or organizations) due to privacy concerns, motivating federated learning. In this work, we focus on federated training of dual encoding models on decentralized data composed of many small, non-IID (independent and identically distributed) client datasets. We show that existing approaches that work well in centralized settings perform poorly when naively adapted to this setting using federated averaging. We observe that, we can simulate large-batch loss computation on individual clients for loss functions that are based on encoding statistics. Based on this insight, we propose a novel federated training approach, Distributed Cross Correlation Optimization (DCCO), which trains dual encoding models using encoding statistics aggregated across clients, without sharing individual data samples. Our experimental results on two datasets demonstrate that the proposed DCCO approach outperforms federated variants of existing approaches by a large margin.

Jiaxing Wu, Lin Ning, Luyang Liu et al.

LLM-powered personalization agent systems employ Large Language Models (LLMs) to predict users' behavior from their past activities. However, their effectiveness often hinges on the ability to effectively leverage extensive, long user historical data due to its inherent noise and length of such data. Existing pretrained LLMs may generate summaries that are concise but lack the necessary context for downstream tasks, hindering their utility in personalization systems. To address these challenges, we introduce Reinforcement Learning from Prediction Feedback (RLPF). RLPF fine-tunes LLMs to generate concise, human-readable user summaries that are optimized for downstream task performance. By maximizing the usefulness of the generated summaries, RLPF effectively distills extensive user history data while preserving essential information for downstream tasks. Our empirical evaluation demonstrates significant improvements in both extrinsic downstream task utility and intrinsic summary quality, surpassing baseline methods by up to 22% on downstream task performance and achieving an up to 84.59% win rate on Factuality, Abstractiveness, and Readability. RLPF also achieves a remarkable 74% reduction in context length while improving performance on 16 out of 19 unseen tasks and/or datasets, showcasing its generalizability. This approach offers a promising solution for enhancing LLM personalization by effectively transforming long, noisy user histories into informative and human-readable representations.

Chao Wang, Neo Wu, Lin Ning et al.

Large language models (LLMs) have shown remarkable capabilities in generating user summaries from a long list of raw user activity data. These summaries capture essential user information such as preferences and interests, and therefore are invaluable for LLM-based personalization applications, such as explainable recommender systems. However, the development of new summarization techniques is hindered by the lack of ground-truth labels, the inherent subjectivity of user summaries, and human evaluation which is often costly and time-consuming. To address these challenges, we introduce \UserSumBench, a benchmark framework designed to facilitate iterative development of LLM-based summarization approaches. This framework offers two key components: (1) A reference-free summary quality metric. We show that this metric is effective and aligned with human preferences across three diverse datasets (MovieLens, Yelp and Amazon Review). (2) A novel robust summarization method that leverages time-hierarchical summarizer and self-critique verifier to produce high-quality summaries while eliminating hallucination. This method serves as a strong baseline for further innovation in summarization techniques.

Khaled Saab, Tao Tu, Wei-Hung Weng et al.

Excellence in a wide variety of medical applications poses considerable challenges for AI, requiring advanced reasoning, access to up-to-date medical knowledge and understanding of complex multimodal data. Gemini models, with strong general capabilities in multimodal and long-context reasoning, offer exciting possibilities in medicine. Building on these core strengths of Gemini, we introduce Med-Gemini, a family of highly capable multimodal models that are specialized in medicine with the ability to seamlessly use web search, and that can be efficiently tailored to novel modalities using custom encoders. We evaluate Med-Gemini on 14 medical benchmarks, establishing new state-of-the-art (SoTA) performance on 10 of them, and surpass the GPT-4 model family on every benchmark where a direct comparison is viable, often by a wide margin. On the popular MedQA (USMLE) benchmark, our best-performing Med-Gemini model achieves SoTA performance of 91.1% accuracy, using a novel uncertainty-guided search strategy. On 7 multimodal benchmarks including NEJM Image Challenges and MMMU (health & medicine), Med-Gemini improves over GPT-4V by an average relative margin of 44.5%. We demonstrate the effectiveness of Med-Gemini's long-context capabilities through SoTA performance on a needle-in-a-haystack retrieval task from long de-identified health records and medical video question answering, surpassing prior bespoke methods using only in-context learning. Finally, Med-Gemini's performance suggests real-world utility by surpassing human experts on tasks such as medical text summarization, alongside demonstrations of promising potential for multimodal medical dialogue, medical research and education. Taken together, our results offer compelling evidence for Med-Gemini's potential, although further rigorous evaluation will be crucial before real-world deployment in this safety-critical domain.

Lin Ning, Luyang Liu, Jiaxing Wu et al.

Large language models (LLMs) have achieved remarkable success across various domains, but effectively incorporating complex and potentially noisy user timeline data into LLMs remains a challenge. Current approaches often involve translating user timelines into text descriptions before feeding them to LLMs, which can be inefficient and may not fully capture the nuances of user behavior. Inspired by how LLMs are effectively integrated with images through direct embeddings, we propose User-LLM, a novel framework that leverages user embeddings to directly contextualize LLMs with user history interactions. These embeddings, generated by a user encoder pretrained using self-supervised learning on diverse user interactions, capture latent user behaviors and interests as well as their evolution over time. We integrate these user embeddings with LLMs through cross-attention, enabling LLMs to dynamically adapt their responses based on the context of a user's past actions and preferences. Our approach achieves significant efficiency gains by representing user timelines directly as embeddings, leading to substantial inference speedups of up to 78.1X. Comprehensive experiments on MovieLens, Amazon Review, and Google Local Review datasets demonstrate that User-LLM outperforms text-prompt-based contextualization on tasks requiring deep user understanding, with improvements of up to 16.33%, particularly excelling on long sequences that capture subtle shifts in user behavior. Furthermore, the incorporation of Perceiver layers streamlines the integration between user encoders and LLMs, yielding additional computational savings.

Warren Morningstar, Alex Bijamov, Chris Duvarney et al.

We study the relative effects of data augmentations, pretraining algorithms, and model architectures in Self-Supervised Learning (SSL). While the recent literature in this space leaves the impression that the pretraining algorithm is of critical importance to performance, understanding its effect is complicated by the difficulty in making objective and direct comparisons between methods. We propose a new framework which unifies many seemingly disparate SSL methods into a single shared template. Using this framework, we identify aspects in which methods differ and observe that in addition to changing the pretraining algorithm, many works also use new data augmentations or more powerful model architectures. We compare several popular SSL methods using our framework and find that many algorithmic additions, such as prediction networks or new losses, have a minor impact on downstream task performance (often less than $1\%$), while enhanced augmentation techniques offer more significant performance improvements ($2-4\%$). Our findings challenge the premise that SSL is being driven primarily by algorithmic improvements, and suggest instead a bitter lesson for SSL: that augmentation diversity and data / model scale are more critical contributors to recent advances in self-supervised learning.

Yuhan Liu, Lin Ning, Neo Wu et al.

User sequence modeling is crucial for modern large-scale recommendation systems, as it enables the extraction of informative representations of users and items from their historical interactions. These user representations are widely used for a variety of downstream tasks to enhance users' online experience. A key challenge for learning these representations is the lack of labeled training data. While self-supervised learning (SSL) methods have emerged as a promising solution for learning representations from unlabeled data, many existing approaches rely on extensive negative sampling, which can be computationally expensive and may not always be feasible in real-world scenario. In this work, we propose an adaptation of Barlow Twins, a state-of-the-art SSL methods, to user sequence modeling by incorporating suitable augmentation methods. Our approach aims to mitigate the need for large negative sample batches, enabling effective representation learning with smaller batch sizes and limited labeled data. We evaluate our method on the MovieLens-1M, MovieLens-20M, and Yelp datasets, demonstrating that our method consistently outperforms the widely-used dual encoder model across three downstream tasks, achieving an 8%-20% improvement in accuracy. Our findings underscore the effectiveness of our approach in extracting valuable sequence-level information for user modeling, particularly in scenarios where labeled data is scarce and negative examples are limited.

Karan Singhal, Tao Tu, Juraj Gottweis et al.

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to physicians has long been viewed as one such grand challenge. Large language models (LLMs) have catalyzed significant progress in medical question answering; Med-PaLM was the first model to exceed a "passing" score in US Medical Licensing Examination (USMLE) style questions with a score of 67.2% on the MedQA dataset. However, this and other prior work suggested significant room for improvement, especially when models' answers were compared to clinicians' answers. Here we present Med-PaLM 2, which bridges these gaps by leveraging a combination of base LLM improvements (PaLM 2), medical domain finetuning, and prompting strategies including a novel ensemble refinement approach. Med-PaLM 2 scored up to 86.5% on the MedQA dataset, improving upon Med-PaLM by over 19% and setting a new state-of-the-art. We also observed performance approaching or exceeding state-of-the-art across MedMCQA, PubMedQA, and MMLU clinical topics datasets. We performed detailed human evaluations on long-form questions along multiple axes relevant to clinical applications. In pairwise comparative ranking of 1066 consumer medical questions, physicians preferred Med-PaLM 2 answers to those produced by physicians on eight of nine axes pertaining to clinical utility (p < 0.001). We also observed significant improvements compared to Med-PaLM on every evaluation axis (p < 0.001) on newly introduced datasets of 240 long-form "adversarial" questions to probe LLM limitations. While further studies are necessary to validate the efficacy of these models in real-world settings, these results highlight rapid progress towards physician-level performance in medical question answering.

Luyang Liu, David Racz, Kara Vaillancourt et al.

Road crashes are the sixth leading cause of lost disability-adjusted life-years (DALYs) worldwide. One major challenge in traffic safety research is the sparsity of crashes, which makes it difficult to achieve a fine-grain understanding of crash causations and predict future crash risk in a timely manner. Hard-braking events have been widely used as a safety surrogate due to their relatively high prevalence and ease of detection with embedded vehicle sensors. As an alternative to using sensors fixed in vehicles, this paper presents a scalable approach for detecting hard-braking events using the kinematics data collected from smartphone sensors. We train a Transformer-based machine learning model for hard-braking event detection using concurrent sensor readings from smartphones and vehicle sensors from drivers who connect their phone to the vehicle while navigating in Google Maps. The detection model shows superior performance with a $0.83$ Area under the Precision-Recall Curve (PR-AUC), which is $3.8\times$better than a GPS speed-based heuristic model, and $166.6\times$better than an accelerometer-based heuristic model. The detected hard-braking events are strongly correlated with crashes from publicly available datasets, supporting their use as a safety surrogate. In addition, we conduct model fairness and selection bias evaluation to ensure that the safety benefits are equally shared. The developed methodology can benefit many safety applications such as identifying safety hot spots at road network level, evaluating the safety of new user interfaces, as well as using routing to improve traffic safety.

Xuhui Jia, Kai Han, Yukun Zhu et al.

This paper studies the problem of novel category discovery on single- and multi-modal data with labels from different but relevant categories. We present a generic, end-to-end framework to jointly learn a reliable representation and assign clusters to unlabelled data. To avoid over-fitting the learnt embedding to labelled data, we take inspiration from self-supervised representation learning by noise-contrastive estimation and extend it to jointly handle labelled and unlabelled data. In particular, we propose using category discrimination on labelled data and cross-modal discrimination on multi-modal data to augment instance discrimination used in conventional contrastive learning approaches. We further employ Winner-Take-All (WTA) hashing algorithm on the shared representation space to generate pairwise pseudo labels for unlabelled data to better predict cluster assignments. We thoroughly evaluate our framework on large-scale multi-modal video benchmarks Kinetics-400 and VGG-Sound, and image benchmarks CIFAR10, CIFAR100 and ImageNet, obtaining state-of-the-art results.

Mark Weber, Jun Xie, Maxwell Collins et al.

The task of assigning semantic classes and track identities to every pixel in a video is called video panoptic segmentation. Our work is the first that targets this task in a real-world setting requiring dense interpretation in both spatial and temporal domains. As the ground-truth for this task is difficult and expensive to obtain, existing datasets are either constructed synthetically or only sparsely annotated within short video clips. To overcome this, we introduce a new benchmark encompassing two datasets, KITTI-STEP, and MOTChallenge-STEP. The datasets contain long video sequences, providing challenging examples and a test-bed for studying long-term pixel-precise segmentation and tracking under real-world conditions. We further propose a novel evaluation metric Segmentation and Tracking Quality (STQ) that fairly balances semantic and tracking aspects of this task and is more appropriate for evaluating sequences of arbitrary length. Finally, we provide several baselines to evaluate the status of existing methods on this new challenging dataset. We have made our datasets, metric, benchmark servers, and baselines publicly available, and hope this will inspire future research.

Xiangyun Zhao, Raviteja Vemulapalli, Philip Mansfield et al.

Collecting labeled data for the task of semantic segmentation is expensive and time-consuming, as it requires dense pixel-level annotations. While recent Convolutional Neural Network (CNN) based semantic segmentation approaches have achieved impressive results by using large amounts of labeled training data, their performance drops significantly as the amount of labeled data decreases. This happens because deep CNNs trained with the de facto cross-entropy loss can easily overfit to small amounts of labeled data. To address this issue, we propose a simple and effective contrastive learning-based training strategy in which we first pretrain the network using a pixel-wise, label-based contrastive loss, and then fine-tune it using the cross-entropy loss. This approach increases intra-class compactness and inter-class separability, thereby resulting in a better pixel classifier. We demonstrate the effectiveness of the proposed training strategy using the Cityscapes and PASCAL VOC 2012 segmentation datasets. Our results show that pretraining with the proposed contrastive loss results in large performance gains (more than 20% absolute improvement in some settings) when the amount of labeled data is limited. In many settings, the proposed contrastive pretraining strategy, which does not use any additional data, is able to match or outperform the widely-used ImageNet pretraining strategy that uses more than a million additional labeled images.

Yandong Li, Xuhui Jia, Ruoxin Sang et al.

This paper is concerned with ranking many pre-trained deep neural networks (DNNs), called checkpoints, for the transfer learning to a downstream task. Thanks to the broad use of DNNs, we may easily collect hundreds of checkpoints from various sources. Which of them transfers the best to our downstream task of interest? Striving to answer this question thoroughly, we establish a neural checkpoint ranking benchmark (NeuCRaB) and study some intuitive ranking measures. These measures are generic, applying to the checkpoints of different output types without knowing how the checkpoints are pre-trained on which dataset. They also incur low computation cost, making them practically meaningful. Our results suggest that the linear separability of the features extracted by the checkpoints is a strong indicator of transferability. We also arrive at a new ranking measure, NLEEP, which gives rise to the best performance in the experiments.

Bardia Doosti, Ching-Hui Chen, Raviteja Vemulapalli et al.

Mutual gaze detection, i.e., predicting whether or not two people are looking at each other, plays an important role in understanding human interactions. In this work, we focus on the task of image-based mutual gaze detection, and propose a simple and effective approach to boost the performance by using an auxiliary 3D gaze estimation task during the training phase. We achieve the performance boost without additional labeling cost by training the 3D gaze estimation branch using pseudo 3D gaze labels deduced from mutual gaze labels. By sharing the head image encoder between the 3D gaze estimation and the mutual gaze detection branches, we achieve better head features than learned by training the mutual gaze detection branch alone. Experimental results on three image datasets show that the proposed approach improves the detection performance significantly without additional annotations. This work also introduces a new image dataset that consists of 33.1K pairs of humans annotated with mutual gaze labels in 29.2K images.

Huiyu Wang, Yukun Zhu, Bradley Green et al.

Convolution exploits locality for efficiency at a cost of missing long range context. Self-attention has been adopted to augment CNNs with non-local interactions. Recent works prove it possible to stack self-attention layers to obtain a fully attentional network by restricting the attention to a local region. In this paper, we attempt to remove this constraint by factorizing 2D self-attention into two 1D self-attentions. This reduces computation complexity and allows performing attention within a larger or even global region. In companion, we also propose a position-sensitive self-attention design. Combining both yields our position-sensitive axial-attention layer, a novel building block that one could stack to form axial-attention models for image classification and dense prediction. We demonstrate the effectiveness of our model on four large-scale datasets. In particular, our model outperforms all existing stand-alone self-attention models on ImageNet. Our Axial-DeepLab improves 2.8% PQ over bottom-up state-of-the-art on COCO test-dev. This previous state-of-the-art is attained by our small variant that is 3.8x parameter-efficient and 27x computation-efficient. Axial-DeepLab also achieves state-of-the-art results on Mapillary Vistas and Cityscapes.

Neo Wu, Bradley Green, Xue Ben et al.

In this paper, we present a new approach to time series forecasting. Time series data are prevalent in many scientific and engineering disciplines. Time series forecasting is a crucial task in modeling time series data, and is an important area of machine learning. In this work we developed a novel method that employs Transformer-based machine learning models to forecast time series data. This approach works by leveraging self-attention mechanisms to learn complex patterns and dynamics from time series data. Moreover, it is a generic framework and can be applied to univariate and multivariate time series data, as well as time series embeddings. Using influenza-like illness (ILI) forecasting as a case study, we show that the forecasting results produced by our approach are favorably comparable to the state-of-the-art.

Yu Liu, Xuhui Jia, Mingxing Tan et al.

Standard Knowledge Distillation (KD) approaches distill the knowledge of a cumbersome teacher model into the parameters of a student model with a pre-defined architecture. However, the knowledge of a neural network, which is represented by the network's output distribution conditioned on its input, depends not only on its parameters but also on its architecture. Hence, a more generalized approach for KD is to distill the teacher's knowledge into both the parameters and architecture of the student. To achieve this, we present a new Architecture-aware Knowledge Distillation (AKD) approach that finds student models (pearls for the teacher) that are best for distilling the given teacher model. In particular, we leverage Neural Architecture Search (NAS), equipped with our KD-guided reward, to search for the best student architectures for a given teacher. Experimental results show our proposed AKD consistently outperforms the conventional NAS plus KD approach, and achieves state-of-the-art results on the ImageNet classification task under various latency settings. Furthermore, the best AKD student architecture for the ImageNet classification task also transfers well to other tasks such as million level face recognition and ensemble learning.