Michael Pfeiffer

Alexander Kugele, Thomas Pfeil, Michael Pfeiffer et al.

Event-based vision sensors encode local pixel-wise brightness changes in streams of events rather than image frames and yield sparse, energy-efficient encodings of scenes, in addition to low latency, high dynamic range, and lack of motion blur. Recent progress in object recognition from event-based sensors has come from conversions of deep neural networks, trained with backpropagation. However, using these approaches for event streams requires a transformation to a synchronous paradigm, which not only loses computational efficiency, but also misses opportunities to extract spatio-temporal features. In this article we propose a hybrid architecture for end-to-end training of deep neural networks for event-based pattern recognition and object detection, combining a spiking neural network (SNN) backbone for efficient event-based feature extraction, and a subsequent analog neural network (ANN) head to solve synchronous classification and detection tasks. This is achieved by combining standard backpropagation with surrogate gradient training to propagate gradients through the SNN. Hybrid SNN-ANNs can be trained without conversion, and result in highly accurate networks that are substantially more computationally efficient than their ANN counterparts. We demonstrate results on event-based classification and object detection datasets, in which only the architecture of the ANN heads need to be adapted to the tasks, and no conversion of the event-based input is necessary. Since ANNs and SNNs require different hardware paradigms to maximize their efficiency, we envision that SNN backbone and ANN head can be executed on different processing units, and thus analyze the necessary bandwidth to communicate between the two parts. Hybrid networks are promising architectures to further advance machine learning approaches for event-based vision, without having to compromise on efficiency.

Korsuk Sirinukunwattana, Josien P. W. Pluim, Hao Chen et al.

Colorectal adenocarcinoma originating in intestinal glandular structures is the most common form of colon cancer. In clinical practice, the morphology of intestinal glands, including architectural appearance and glandular formation, is used by pathologists to inform prognosis and plan the treatment of individual patients. However, achieving good inter-observer as well as intra-observer reproducibility of cancer grading is still a major challenge in modern pathology. An automated approach which quantifies the morphology of glands is a solution to the problem. This paper provides an overview to the Gland Segmentation in Colon Histology Images Challenge Contest (GlaS) held at MICCAI'2015. Details of the challenge, including organization, dataset and evaluation criteria, are presented, along with the method descriptions and evaluation results from the top performing methods.

Philipp Kainz, Michael Pfeiffer, Martin Urschler

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing methods. As part of the GlaS@MICCAI2015 colon gland segmentation challenge, we present a learning-based algorithm to segment glands in tissue of benign and malignant colorectal cancer. Images are preprocessed according to the Hematoxylin-Eosin staining protocol and two deep convolutional neural networks (CNN) are trained as pixel classifiers. The CNN predictions are then regularized using a figure-ground segmentation based on weighted total variation to produce the final segmentation result. On two test sets, our approach achieves a tissue classification accuracy of 98% and 94%, making use of the inherent capability of our system to distinguish between benign and malignant tissue.