Silvia Mura

Silvia Mura, Elisabetta Marini, Maurizio Magarini et al.

Sub-terahertz (sub-THz) and terahertz (THz) radiation offer unique opportunities for non-invasive diagnostics and imaging due to their sensitivity to water content and molecular dynamics in biological tissues. In this work, a comprehensive dielectric model of human skin and its cellular constituents is developed across these frequency ranges. The model combines multi-Debye relaxation theory with effective medium formulations to account for intracellular water dynamics and macromolecular relaxation processes. Key cellular parameters, including water content, protein and lipid fractions, and ionic conductivity, are integrated from experimentally validated sources. The proposed framework enables realistic predictions of frequency-dependent permittivity for different skin layers and cell types, providing a physically interpretable description of sub-THz and THz tissue interactions. This approach establishes a foundation for the design and optimization of next-generation diagnostic and imaging techniques operating in these frequency bands.

Elisabetta Marini, Silvia Mura, Marco Hernandez et al.

Terahertz (THz) radiation provides a non-ionizing, highly sensitive probe of the dielectric properties of biological tissues. In this study, we present a comprehensive experimental characterization of dielectric properties using pork skin tissue, a widely used surrogate for human tissue, as a biological sample. Measurements are conducted employing THz time-domain spectroscopy in the 0.1-11 THz frequency range with photoconductive antennas for both signal generation and detection. Frequency-dependent refractive indices, absorption, and complex permittivity are extracted from transmitted time-domain signals. Our results confirm strong absorption and low transmittance at low THz frequencies due to water content, while highlighting frequency-dependent dispersion and narrowband transmission features at higher frequencies. This work provides one of the first extended-frequency datasets of biological tissue dielectric properties, supporting realistic channel modeling for the design and development of intra-body nanosensor networks in the THz band.

Silvia Mura, Davide Scazzoli, Lorenzo Fineschi et al.

This study presents a comprehensive experimental assessment of a low-cost frequency-modulated continuous-wave (FMCW) multiple-input multiple-output (MIMO) radar for non-contact vital sign monitoring, focusing on respiratory rate (RR) and heart rate (HR) estimation. The influence of sensing distance and number of transmitted chirps on measurement accuracy is systematically quantified. Results exhibit a U-shaped error profile with optimal performance near $70~cm$, achieving mean absolute errors of $0.8~bpm$ for RR and $3.2~bpm$ for HR. Accuracy deteriorates at short ($<60~cm$) and long ($>100~cm$) distances due to multipath, near-field, and signal-to-noise effects. Increasing chirp count enhances performance: RR errors converge asymptotically for $\geq96$ chirps, while HR requires at least 96 chirps for stable detection. Variability metrics, including heart and respiratory rate variability, remain less accurate ($>15$--$30\%$ error), indicating limited capability in capturing instantaneous fluctuations. These findings define a fundamental trade-off: the radar ensures robust estimation of average RR and HR but exhibits restricted precision in high-resolution beat-to-beat and breath-to-breath monitoring.

Silvia Mura, Chiara Cavigliano, Anna Marcucci et al.

This paper presents a systematic characterization of wearable galvanic coupling (GC) channels under narrowband and wideband operation. A physics-consistent digital human twin maps anatomical properties, propagation geometry, and electrode-skin interfaces into complex transfer functions directly usable for communication analysis. Attenuation, phase delay, and group delay are evaluated for longitudinal and radial configurations, and dispersion-induced variability is quantified through attenuation ripple and delay standard deviation metrics versus bandwidth. Results confirm electro-quasistatic, weakly dispersive behavior over 10 kHz-1 MHz. Attenuation is primarily geometry-driven, whereas amplitude ripple and delay variability increase with bandwidth, tightening equalization and synchronization constraints. Interface conditioning (gel and foam) significantly improves amplitude and phase stability, while propagation geometry governs link budget and baseline delay. Overall, the framework quantitatively links tissue electromagnetics to waveform distortion, enabling informed trade-offs among bandwidth, interface design, and transceiver complexity in wearable GC systems.

Arek Berc Gokdag, Silvia Mura, Antonio Coviello et al.

Peripheral nerve interfaces (PNIs) facilitate neural recording and stimulation for treating nerve injuries, but real-time classification of electroneurographic (ENG) signals remains challenging due to constraints on complexity and latency, particularly in implantable devices. This study introduces MobilESCAPE-Net, a lightweight architecture that reduces computational cost while maintaining and slightly improving classification performance. Compared to the state-of-the-art ESCAPE-Net, MobilESCAPE-Net achieves comparable accuracy and F1-score with significantly lower complexity, reducing trainable parameters by 99.9\% and floating point operations per second by 92.47\%, enabling faster inference and real-time processing. Its efficiency makes it well-suited for low-complexity ENG signal classification in resource-constrained environments such as implantable devices.