Vanessa Borst

Vanessa Borst, Timo Dittus, Konstantin Müller et al.

The aging population poses numerous challenges to healthcare, including the increase in chronic wounds in the elderly. The current approach to wound assessment by therapists based on photographic documentation is subjective, highlighting the need for computer-aided wound recognition from smartphone photos. This offers objective and convenient therapy monitoring, while being accessible to patients from their home at any time. However, despite research in mobile image segmentation, there is a lack of focus on mobile wound segmentation. To address this gap, we conduct initial research on three lightweight architectures to investigate their suitability for smartphone-based wound segmentation. Using public datasets and UNet as a baseline, our results are promising, with both ENet and TopFormer, as well as the larger UNeXt variant, showing comparable performance to UNet. Furthermore, we deploy the models into a smartphone app for visual assessment of live segmentation, where results demonstrate the effectiveness of TopFormer in distinguishing wounds from wound-coloured objects. While our study highlights the potential of transformer models for mobile wound segmentation, future work should aim to further improve the mask contours.

Robert Leppich, Michael Stenger, Daniel Grillmeyer et al.

We introduce a temporal feature encoding architecture called Time Series Representation Model (TSRM) for multivariate time series forecasting and imputation. The architecture is structured around CNN-based representation layers, each dedicated to an independent representation learning task and designed to capture diverse temporal patterns, followed by an attention-based feature extraction layer and a merge layer, designed to aggregate extracted features. The architecture is fundamentally based on a configuration that is inspired by a Transformer encoder, with self-attention mechanisms at its core. The TSRM architecture outperforms state-of-the-art approaches on most of the seven established benchmark datasets considered in our empirical evaluation for both forecasting and imputation tasks. At the same time, it significantly reduces complexity in the form of learnable parameters. The source code is available at https://github.com/RobertLeppich/TSRM.

Vanessa Borst, Samuel Kounev

Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support systems. Over the past decade, numerous architectures specifically tailored to medical imaging have emerged to address domain-specific challenges such as low contrast, small anatomical structures, and limited annotated data. In parallel, rapid progress in computer vision has produced highly capable general-purpose vision models (GP-VMs) originally designed for natural images. Despite their strong performance on standard vision benchmarks, their effectiveness for MIS remains insufficiently understood. In this work, we conduct a controlled empirical study to examine whether specialized medical segmentation architectures (SMAs) provide systematic advantages over modern GP-VMs for 2D MIS. We compare eleven SMAs and GP-VMs using a unified training and evaluation protocol. Experiments are performed across three heterogeneous datasets covering different imaging modalities, class structures, and data characteristics. Beyond segmentation accuracy, we analyze qualitative Grad-CAM visualizations to investigate explainability (XAI) behavior. Our results demonstrate that, for the analyzed datasets, GP-VMs out-perform the majority of specialized MIS models. Moreover, XAI analyses indicate that GP-VMs can capture clinically relevant structures without explicit domain-specific architectural design. These findings suggest that GP-VMs can represent a viable alternative to domain-specific methods, highlighting the importance of informed model selection for end-to-end MIS systems. All code and resources are available at GitHub.

Vanessa Borst, Timo Dittus, Tassilo Dege et al.

Chronic wounds affect a large population, particularly the elderly and diabetic patients, who often exhibit limited mobility and co-existing health conditions. Automated wound monitoring via mobile image capture can reduce in-person physician visits by enabling remote tracking of wound size. Semantic segmentation is key to this process, yet wound segmentation remains underrepresented in medical imaging research. To address this, we benchmark state-of-the-art deep learning models from general-purpose vision, medical imaging, and top methods from public wound challenges. For a fair comparison, we standardize training, data augmentation, and evaluation, conducting cross-validation to minimize partitioning bias. We also assess real-world deployment aspects, including generalization to an out-of-distribution wound dataset, computational efficiency, and interpretability. Additionally, we propose a reference object-based approach to convert AI-generated masks into clinically relevant wound size estimates and evaluate this, along with mask quality, for the five best architectures based on physician assessments. Overall, the transformer-based TransNeXt showed the highest levels of generalizability. Despite variations in inference times, all models processed at least one image per second on the CPU, which is deemed adequate for the intended application. Interpretability analysis typically revealed prominent activations in wound regions, emphasizing focus on clinically relevant features. Expert evaluation showed high mask approval for all analyzed models, with VWFormer and ConvNeXtS backbone performing the best. Size retrieval accuracy was similar across models, and predictions closely matched expert annotations. Finally, we demonstrate how our AI-driven wound size estimation framework, WoundAmbit, is integrated into a custom telehealth system.