Cesare Barbera

Cesare Barbera, Lorenzo Perini, Giovanni De Toni et al.

Accurate and well-calibrated Machine Learning (ML) models are mandatory in high-stakes settings, yet effective multiclass calibration remains challenging: global approaches assume calibration errors are homogeneous across the latent space, while local methods often rely on latent-space dimensionality reduction, which leads to information loss. To address these issues, we propose a compositional approach to multiclass calibration, where region-specific calibration maps are constructed from shared codeword-dependent factors. We instantiate this idea via Vector Quantization (VQ), which induces a structured partition of the representation space, and an indexed parameterization of Dirichlet concentrations that enables parameter sharing across regions. Our approach learns heterogeneous calibration maps that generalize well even to sparse regions of the latent space. Experiments on benchmark datasets show significant improvements in local calibration while maintaining competitive global calibration and predictive performance.

Cesare Barbera, Lorenzo Perini, Giovanni De Toni et al.

Developing trustworthy Machine Learning (ML) models requires their predicted probabilities to be well-calibrated, meaning they should reflect true-class frequencies. Among calibration notions in multiclass classification, strong calibration is the most stringent, as it requires all predicted probabilities to be simultaneously calibrated across all classes. However, existing approaches to multiclass calibration lack a notion of distance among inputs, which makes them vulnerable to proximity bias: predictions in sparse regions of the feature space are systematically miscalibrated. This is especially relevant in high-stakes settings, such as healthcare, where the sparse instances are exactly those most at risk of biased treatment. In this work, we address this main shortcoming by introducing a local perspective on multiclass calibration. First, we formally define multiclass local calibration and establish its relationship with strong calibration. Second, we theoretically analyze the pitfalls of existing evaluation metrics when applied to multiclass local calibration. Third, we propose a practical method for enhancing local calibration in Neural Networks, which enforces alignment between predicted probabilities and local estimates of class frequencies using the Jensen-Shannon distance. Finally, we empirically validate our approach against existing multiclass calibration techniques.

Ipek Baris Schlicht, Burcu Sayin, Zhixue Zhao et al.

Equitable access to reliable health information is vital when integrating AI into healthcare. Yet, information quality varies across languages, raising concerns about the reliability and consistency of multilingual Large Language Models (LLMs). We systematically examine cross-lingual disparities in pre-training source and factuality alignment in LLM answers for multilingual healthcare Q&A across English, German, Turkish, Chinese (Mandarin), and Italian. We (i) constructed Multilingual Wiki Health Care (MultiWikiHealthCare), a multilingual dataset from Wikipedia; (ii) analyzed cross-lingual healthcare coverage; (iii) assessed LLM response alignment with these references; and (iv) conducted a case study on factual alignment through the use of contextual information and Retrieval-Augmented Generation (RAG). Our findings reveal substantial cross-lingual disparities in both Wikipedia coverage and LLM factual alignment. Across LLMs, responses align more with English Wikipedia, even when the prompts are non-English. Providing contextual excerpts from non-English Wikipedia at inference time effectively shifts factual alignment toward culturally relevant knowledge. These results highlight practical pathways for building more equitable, multilingual AI systems for healthcare.

Andrea Pugnana, Giovanni De Toni, Cesare Barbera et al.

Developing decision-support systems that complement human performance in classification tasks remains an open challenge. A popular approach, Learning to Defer (LtD), allows a Machine Learning (ML) model to pass difficult cases to a human expert. However, LtD treats humans and ML models as mutually exclusive decision-makers, restricting the expert contribution to mere predictions. To address this limitation, we propose Learning to Ask (LtA), a new framework that handles both when and how to incorporate expert input in an ML model. LtA is based on a two-part architecture: a standard ML model and an enriched model trained with additional expert human feedback, with a formally optimal strategy for selecting when to query the enriched model. We provide two practical implementations of LtA: a sequential approach, which trains the models in stages, and a joint approach, which optimises them simultaneously. For the latter, we design surrogate losses with realisable-consistency guarantees. Our experiments with synthetic and real expert data demonstrate that LtA provides a more flexible and powerful foundation for effective human-AI collaboration.