20.8CVApr 20, 2022
Human-Object Interaction Detection via Disentangled TransformerDesen Zhou, Zhichao Liu, Jian Wang et al.
Human-Object Interaction Detection tackles the problem of joint localization and classification of human object interactions. Existing HOI transformers either adopt a single decoder for triplet prediction, or utilize two parallel decoders to detect individual objects and interactions separately, and compose triplets by a matching process. In contrast, we decouple the triplet prediction into human-object pair detection and interaction classification. Our main motivation is that detecting the human-object instances and classifying interactions accurately needs to learn representations that focus on different regions. To this end, we present Disentangled Transformer, where both encoder and decoder are disentangled to facilitate learning of two sub-tasks. To associate the predictions of disentangled decoders, we first generate a unified representation for HOI triplets with a base decoder, and then utilize it as input feature of each disentangled decoder. Extensive experiments show that our method outperforms prior work on two public HOI benchmarks by a sizeable margin. Code will be available.
TriVol: Point Cloud Rendering via Triple VolumesTao Hu, Xiaogang Xu, Ruihang Chu et al.
Existing learning-based methods for point cloud rendering adopt various 3D representations and feature querying mechanisms to alleviate the sparsity problem of point clouds. However, artifacts still appear in rendered images, due to the challenges in extracting continuous and discriminative 3D features from point clouds. In this paper, we present a dense while lightweight 3D representation, named TriVol, that can be combined with NeRF to render photo-realistic images from point clouds. Our TriVol consists of triple slim volumes, each of which is encoded from the point cloud. TriVol has two advantages. First, it fuses respective fields at different scales and thus extracts local and non-local features for discriminative representation. Second, since the volume size is greatly reduced, our 3D decoder can be efficiently inferred, allowing us to increase the resolution of the 3D space to render more point details. Extensive experiments on different benchmarks with varying kinds of scenes/objects demonstrate our framework's effectiveness compared with current approaches. Moreover, our framework has excellent generalization ability to render a category of scenes/objects without fine-tuning.
Shuffle Mamba: State Space Models with Random Shuffle for Multi-Modal Image FusionKe Cao, Xuanhua He, Tao Hu et al.
Multi-modal image fusion integrates complementary information from different modalities to produce enhanced and informative images. Although State-Space Models, such as Mamba, are proficient in long-range modeling with linear complexity, most Mamba-based approaches use fixed scanning strategies, which can introduce biased prior information. To mitigate this issue, we propose a novel Bayesian-inspired scanning strategy called Random Shuffle, supplemented by a theoretically feasible inverse shuffle to maintain information coordination invariance, aiming to eliminate biases associated with fixed sequence scanning. Based on this transformation pair, we customized the Shuffle Mamba Framework, penetrating modality-aware information representation and cross-modality information interaction across spatial and channel axes to ensure robust interaction and an unbiased global receptive field for multi-modal image fusion. Furthermore, we develop a testing methodology based on Monte-Carlo averaging to ensure the model's output aligns more closely with expected results. Extensive experiments across multiple multi-modal image fusion tasks demonstrate the effectiveness of our proposed method, yielding excellent fusion quality compared to state-of-the-art alternatives. The code is available at https://github.com/caoke-963/Shuffle-Mamba.
3.3QMAug 23, 2023
Enhancing cardiovascular risk prediction through AI-enabled calcium-omicsAmmar Hoori, Sadeer Al-Kindi, Tao Hu et al.
Background. Coronary artery calcium (CAC) is a powerful predictor of major adverse cardiovascular events (MACE). Traditional Agatston score simply sums the calcium, albeit in a non-linear way, leaving room for improved calcification assessments that will more fully capture the extent of disease. Objective. To determine if AI methods using detailed calcification features (i.e., calcium-omics) can improve MACE prediction. Methods. We investigated additional features of calcification including assessment of mass, volume, density, spatial distribution, territory, etc. We used a Cox model with elastic-net regularization on 2457 CT calcium score (CTCS) enriched for MACE events obtained from a large no-cost CLARIFY program (ClinicalTri-als.gov Identifier: NCT04075162). We employed sampling techniques to enhance model training. We also investigated Cox models with selected features to identify explainable high-risk characteristics. Results. Our proposed calcium-omics model with modified synthetic down sampling and up sampling gave C-index (80.5%/71.6%) and two-year AUC (82.4%/74.8%) for (80:20, training/testing), respectively (sampling was applied to the training set only). Results compared favorably to Agatston which gave C-index (71.3%/70.3%) and AUC (71.8%/68.8%), respectively. Among calcium-omics features, numbers of calcifications, LAD mass, and diffusivity (a measure of spatial distribution) were important determinants of increased risk, with dense calcification (>1000HU) associated with lower risk. The calcium-omics model reclassified 63% of MACE patients to the high risk group in a held-out test. The categorical net-reclassification index was NRI=0.153. Conclusions. AI analysis of coronary calcification can lead to improved results as compared to Agatston scoring. Our findings suggest the utility of calcium-omics in improved prediction of risk.
15.7CVAug 18, 2023
HumanLiff: Layer-wise 3D Human Generation with Diffusion ModelShoukang Hu, Fangzhou Hong, Tao Hu et al.
3D human generation from 2D images has achieved remarkable progress through the synergistic utilization of neural rendering and generative models. Existing 3D human generative models mainly generate a clothed 3D human as an undetectable 3D model in a single pass, while rarely considering the layer-wise nature of a clothed human body, which often consists of the human body and various clothes such as underwear, outerwear, trousers, shoes, etc. In this work, we propose HumanLiff, the first layer-wise 3D human generative model with a unified diffusion process. Specifically, HumanLiff firstly generates minimal-clothed humans, represented by tri-plane features, in a canonical space, and then progressively generates clothes in a layer-wise manner. In this way, the 3D human generation is thus formulated as a sequence of diffusion-based 3D conditional generation. To reconstruct more fine-grained 3D humans with tri-plane representation, we propose a tri-plane shift operation that splits each tri-plane into three sub-planes and shifts these sub-planes to enable feature grid subdivision. To further enhance the controllability of 3D generation with 3D layered conditions, HumanLiff hierarchically fuses tri-plane features and 3D layered conditions to facilitate the 3D diffusion model learning. Extensive experiments on two layer-wise 3D human datasets, SynBody (synthetic) and TightCap (real-world), validate that HumanLiff significantly outperforms state-of-the-art methods in layer-wise 3D human generation. Our code will be available at https://skhu101.github.io/HumanLiff.
Query by Activity Video in the WildTao Hu, William Thong, Pascal Mettes et al.
This paper focuses on activity retrieval from a video query in an imbalanced scenario. In current query-by-activity-video literature, a common assumption is that all activities have sufficient labelled examples when learning an embedding. This assumption does however practically not hold, as only a portion of activities have many examples, while other activities are only described by few examples. In this paper, we propose a visual-semantic embedding network that explicitly deals with the imbalanced scenario for activity retrieval. Our network contains two novel modules. The visual alignment module performs a global alignment between the input video and fixed-sized visual bank representations for all activities. The semantic module performs an alignment between the input video and fixed-sized semantic activity representations. By matching videos with both visual and semantic activity representations that are of equal size over all activities, we no longer ignore infrequent activities during retrieval. Experiments on a new imbalanced activity retrieval benchmark show the effectiveness of our approach for all types of activities.
ID-Animator: Zero-Shot Identity-Preserving Human Video GenerationXuanhua He, Quande Liu, Shengju Qian et al.
Generating high-fidelity human video with specified identities has attracted significant attention in the content generation community. However, existing techniques struggle to strike a balance between training efficiency and identity preservation, either requiring tedious case-by-case fine-tuning or usually missing identity details in the video generation process. In this study, we present \textbf{ID-Animator}, a zero-shot human-video generation approach that can perform personalized video generation given a single reference facial image without further training. ID-Animator inherits existing diffusion-based video generation backbones with a face adapter to encode the ID-relevant embeddings from learnable facial latent queries. To facilitate the extraction of identity information in video generation, we introduce an ID-oriented dataset construction pipeline that incorporates unified human attributes and action captioning techniques from a constructed facial image pool. Based on this pipeline, a random reference training strategy is further devised to precisely capture the ID-relevant embeddings with an ID-preserving loss, thus improving the fidelity and generalization capacity of our model for ID-specific video generation. Extensive experiments demonstrate the superiority of ID-Animator to generate personalized human videos over previous models. Moreover, our method is highly compatible with popular pre-trained T2V models like animatediff and various community backbone models, showing high extendability in real-world applications for video generation where identity preservation is highly desired. Our codes and checkpoints are released at https://github.com/ID-Animator/ID-Animator.
Learning to Generate Dense Point Clouds with Textures on Multiple CategoriesTao Hu, Geng Lin, Zhizhong Han et al.
3D reconstruction from images is a core problem in computer vision. With recent advances in deep learning, it has become possible to recover plausible 3D shapes even from single RGB images for the first time. However, obtaining detailed geometry and texture for objects with arbitrary topology remains challenging. In this paper, we propose a novel approach for reconstructing point clouds from RGB images. Unlike other methods, we can recover dense point clouds with hundreds of thousands of points, and we also include RGB textures. In addition, we train our model on multiple categories which leads to superior generalization to unseen categories compared to previous techniques. We achieve this using a two-stage approach, where we first infer an object coordinate map from the input RGB image, and then obtain the final point cloud using a reprojection and completion step. We show results on standard benchmarks that demonstrate the advantages of our technique. Code is available at https://github.com/TaoHuUMD/3D-Reconstruction.
Real Time Visual Tracking using Spatial-Aware Temporal Aggregation NetworkTao Hu, Lichao Huang, Xianming Liu et al.
More powerful feature representations derived from deep neural networks benefit visual tracking algorithms widely. However, the lack of exploitation on temporal information prevents tracking algorithms from adapting to appearances changing or resisting to drift. This paper proposes a correlation filter based tracking method which aggregates historical features in a spatial-aligned and scale-aware paradigm. The features of historical frames are sampled and aggregated to search frame according to a pixel-level alignment module based on deformable convolutions. In addition, we also use a feature pyramid structure to handle motion estimation at different scales, and address the different demands on feature granularity between tracking losses and deformation offset learning. By this design, the tracker, named as Spatial-Aware Temporal Aggregation network (SATA), is able to assemble appearances and motion contexts of various scales in a time period, resulting in better performance compared to a single static image. Our tracker achieves leading performance in OTB2013, OTB2015, VOT2015, VOT2016 and LaSOT, and operates at a real-time speed of 26 FPS, which indicates our method is effective and practical. Our code will be made publicly available at \href{https://github.com/ecart18/SATA}{https://github.com/ecart18/SATA}.
1.4LGFeb 16
Traceable Latent Variable Discovery Based on Multi-Agent CollaborationHuaming Du, Tao Hu, Yijie Huang et al.
Revealing the underlying causal mechanisms in the real world is crucial for scientific and technological progress. Despite notable advances in recent decades, the lack of high-quality data and the reliance of traditional causal discovery algorithms (TCDA) on the assumption of no latent confounders, as well as their tendency to overlook the precise semantics of latent variables, have long been major obstacles to the broader application of causal discovery. To address this issue, we propose a novel causal modeling framework, TLVD, which integrates the metadata-based reasoning capabilities of large language models (LLMs) with the data-driven modeling capabilities of TCDA for inferring latent variables and their semantics. Specifically, we first employ a data-driven approach to construct a causal graph that incorporates latent variables. Then, we employ multi-LLM collaboration for latent variable inference, modeling this process as a game with incomplete information and seeking its Bayesian Nash Equilibrium (BNE) to infer the possible specific latent variables. Finally, to validate the inferred latent variables across multiple real-world web-based data sources, we leverage LLMs for evidence exploration to ensure traceability. We comprehensively evaluate TLVD on three de-identified real patient datasets provided by a hospital and two benchmark datasets. Extensive experimental results confirm the effectiveness and reliability of TLVD, with average improvements of 32.67% in Acc, 62.21% in CAcc, and 26.72% in ECit across the five datasets.
10.5CVApr 1, 2024
SurMo: Surface-based 4D Motion Modeling for Dynamic Human RenderingTao Hu, Fangzhou Hong, Ziwei Liu
Dynamic human rendering from video sequences has achieved remarkable progress by formulating the rendering as a mapping from static poses to human images. However, existing methods focus on the human appearance reconstruction of every single frame while the temporal motion relations are not fully explored. In this paper, we propose a new 4D motion modeling paradigm, SurMo, that jointly models the temporal dynamics and human appearances in a unified framework with three key designs: 1) Surface-based motion encoding that models 4D human motions with an efficient compact surface-based triplane. It encodes both spatial and temporal motion relations on the dense surface manifold of a statistical body template, which inherits body topology priors for generalizable novel view synthesis with sparse training observations. 2) Physical motion decoding that is designed to encourage physical motion learning by decoding the motion triplane features at timestep t to predict both spatial derivatives and temporal derivatives at the next timestep t+1 in the training stage. 3) 4D appearance decoding that renders the motion triplanes into images by an efficient volumetric surface-conditioned renderer that focuses on the rendering of body surfaces with motion learning conditioning. Extensive experiments validate the state-of-the-art performance of our new paradigm and illustrate the expressiveness of surface-based motion triplanes for rendering high-fidelity view-consistent humans with fast motions and even motion-dependent shadows. Our project page is at: https://taohuumd.github.io/projects/SurMo/
5.2CVJan 28, 2024
Pericoronary adipose tissue feature analysis in CT calcium score images with comparison to coronary CTAYingnan Song, Hao Wu, Juhwan Lee et al.
We investigated the feasibility and advantages of using non-contrast CT calcium score (CTCS) images to assess pericoronary adipose tissue (PCAT) and its association with major adverse cardiovascular events (MACE). PCAT features from coronary CTA (CCTA) have been shown to be associated with cardiovascular risk but are potentially confounded by iodine. If PCAT in CTCS images can be similarly analyzed, it would avoid this issue and enable its inclusion in formal risk assessment from readily available, low-cost CTCS images. To identify coronaries in CTCS images that have subtle visual evidence of vessels, we registered CTCS with paired CCTA images having coronary labels. We developed a novel axial-disk method giving regions for analyzing PCAT features in three main coronary arteries. We analyzed novel hand-crafted and radiomic features using univariate and multivariate logistic regression prediction of MACE and compared results against those from CCTA. Registration accuracy was sufficient to enable the identification of PCAT regions in CTCS images. Motion or beam hardening artifacts were often present in high-contrast CCTA but not CTCS. Mean HU and volume were increased in both CTCS and CCTA for MACE group. There were significant positive correlations between some CTCS and CCTA features, suggesting that similar characteristics were obtained. Using hand-crafted/radiomics from CTCS and CCTA, AUCs were 0.82/0.79 and 0.83/0.77 respectively, while Agatston gave AUC=0.73. Preliminarily, PCAT features can be assessed from three main coronary arteries in non-contrast CTCS images with performance characteristics that are at the very least comparable to CCTA.
15.9CVDec 19, 2021
HVTR: Hybrid Volumetric-Textural Rendering for Human AvatarsTao Hu, Tao Yu, Zerong Zheng et al.
We propose a novel neural rendering pipeline, Hybrid Volumetric-Textural Rendering (HVTR), which synthesizes virtual human avatars from arbitrary poses efficiently and at high quality. First, we learn to encode articulated human motions on a dense UV manifold of the human body surface. To handle complicated motions (e.g., self-occlusions), we then leverage the encoded information on the UV manifold to construct a 3D volumetric representation based on a dynamic pose-conditioned neural radiance field. While this allows us to represent 3D geometry with changing topology, volumetric rendering is computationally heavy. Hence we employ only a rough volumetric representation using a pose-conditioned downsampled neural radiance field (PD-NeRF), which we can render efficiently at low resolutions. In addition, we learn 2D textural features that are fused with rendered volumetric features in image space. The key advantage of our approach is that we can then convert the fused features into a high-resolution, high-quality avatar by a fast GAN-based textural renderer. We demonstrate that hybrid rendering enables HVTR to handle complicated motions, render high-quality avatars under user-controlled poses/shapes and even loose clothing, and most importantly, be efficient at inference time. Our experimental results also demonstrate state-of-the-art quantitative results.
GaTector: A Unified Framework for Gaze Object PredictionBinglu Wang, Tao Hu, Baoshan Li et al.
Gaze object prediction is a newly proposed task that aims to discover the objects being stared at by humans. It is of great application significance but still lacks a unified solution framework. An intuitive solution is to incorporate an object detection branch into an existing gaze prediction method. However, previous gaze prediction methods usually use two different networks to extract features from scene image and head image, which would lead to heavy network architecture and prevent each branch from joint optimization. In this paper, we build a novel framework named GaTector to tackle the gaze object prediction problem in a unified way. Particularly, a specific-general-specific (SGS) feature extractor is firstly proposed to utilize a shared backbone to extract general features for both scene and head images. To better consider the specificity of inputs and tasks, SGS introduces two input-specific blocks before the shared backbone and three task-specific blocks after the shared backbone. Specifically, a novel Defocus layer is designed to generate object-specific features for the object detection task without losing information or requiring extra computations. Moreover, the energy aggregation loss is introduced to guide the gaze heatmap to concentrate on the stared box. In the end, we propose a novel wUoC metric that can reveal the difference between boxes even when they share no overlapping area. Extensive experiments on the GOO dataset verify the superiority of our method in all three tracks, i.e. object detection, gaze estimation, and gaze object prediction.
10.0CVJul 28, 2021
CRD-CGAN: Category-Consistent and Relativistic Constraints for Diverse Text-to-Image GenerationTao Hu, Chengjiang Long, Chunxia Xiao
Generating photo-realistic images from a text description is a challenging problem in computer vision. Previous works have shown promising performance to generate synthetic images conditional on text by Generative Adversarial Networks (GANs). In this paper, we focus on the category-consistent and relativistic diverse constraints to optimize the diversity of synthetic images. Based on those constraints, a category-consistent and relativistic diverse conditional GAN (CRD-CGAN) is proposed to synthesize $K$ photo-realistic images simultaneously. We use the attention loss and diversity loss to improve the sensitivity of the GAN to word attention and noises. Then, we employ the relativistic conditional loss to estimate the probability of relatively real or fake for synthetic images, which can improve the performance of basic conditional loss. Finally, we introduce a category-consistent loss to alleviate the over-category issues between K synthetic images. We evaluate our approach using the Birds-200-2011, Oxford-102 flower and MSCOCO 2014 datasets, and the extensive experiments demonstrate superiority of the proposed method in comparison with state-of-the-art methods in terms of photorealistic and diversity of the generated synthetic images.
3.3CVMar 5, 2020
Hierarchical Modes Exploring in Generative Adversarial NetworksMengxiao Hu, Jinlong Li, Maolin Hu et al.
In conditional Generative Adversarial Networks (cGANs), when two different initial noises are concatenated with the same conditional information, the distance between their outputs is relatively smaller, which makes minor modes likely to collapse into large modes. To prevent this happen, we proposed a hierarchical mode exploring method to alleviate mode collapse in cGANs by introducing a diversity measurement into the objective function as the regularization term. We also introduced the Expected Ratios of Expansion (ERE) into the regularization term, by minimizing the sum of differences between the real change of distance and ERE, we can control the diversity of generated images w.r.t specific-level features. We validated the proposed algorithm on four conditional image synthesis tasks including categorical generation, paired and un-paired image translation and text-to-image generation. Both qualitative and quantitative results show that the proposed method is effective in alleviating the mode collapse problem in cGANs, and can control the diversity of output images w.r.t specific-level features.
4.2CVMar 4, 2020
Multi-object Tracking via End-to-end Tracklet Searching and RankingTao Hu, Lichao Huang, Han Shen
Recent works in multiple object tracking use sequence model to calculate the similarity score between the detections and the previous tracklets. However, the forced exposure to ground-truth in the training stage leads to the training-inference discrepancy problem, i.e., exposure bias, where association error could accumulate in the inference and make the trajectories drift. In this paper, we propose a novel method for optimizing tracklet consistency, which directly takes the prediction errors into account by introducing an online, end-to-end tracklet search training process. Notably, our methods directly optimize the whole tracklet score instead of pairwise affinity. With sequence model as appearance encoders of tracklet, our tracker achieves remarkable performance gain from conventional tracklet association baseline. Our methods have also achieved state-of-the-art in MOT15~17 challenge benchmarks using public detection and online settings.
1.8CVJul 26, 2019
VITAL: A Visual Interpretation on Text with Adversarial Learning for Image LabelingTao Hu, Chengjiang Long, Leheng Zhang et al.
In this paper, we propose a novel way to interpret text information by extracting visual feature presentation from multiple high-resolution and photo-realistic synthetic images generated by Text-to-image Generative Adversarial Network (GAN) to improve the performance of image labeling. Firstly, we design a stacked Generative Multi-Adversarial Network (GMAN), StackGMAN++, a modified version of the current state-of-the-art Text-to-image GAN, StackGAN++, to generate multiple synthetic images with various prior noises conditioned on a text. And then we extract deep visual features from the generated synthetic images to explore the underlying visual concepts for text. Finally, we combine image-level visual feature, text-level feature and visual features based on synthetic images together to predict labels for images. We conduct experiments on two benchmark datasets and the experimental results clearly demonstrate the efficacy of our proposed approach.
14.2CVApr 17, 2019
Render4Completion: Synthesizing Multi-View Depth Maps for 3D Shape CompletionTao Hu, Zhizhong Han, Abhinav Shrivastava et al.
We propose a novel approach for 3D shape completion by synthesizing multi-view depth maps. While previous work for shape completion relies on volumetric representations, meshes, or point clouds, we propose to use multi-view depth maps from a set of fixed viewing angles as our shape representation. This allows us to be free of the limitations of memory for volumetric representations and point clouds by casting shape completion into an image-to-image translation problem. Specifically, we render depth maps of the incomplete shape from a fixed set of viewpoints, and perform depth map completion in each view. Different from image-to-image translation network that completes each view separately, our novel network, multi-view completion net (MVCN), leverages information from all views of a 3D shape to help the completion of each single view. This enables MVCN to leverage more information from different depth views to achieve high accuracy in single depth view completion and keep the consistency among the completed depth images in different views. Benefited by the multi-view representation and the novel network structure, MVCN significantly improves the accuracy of 3D shape completion in large-scale benchmarks compared to the state of the art.
5.9NCMay 12, 2014
A Neuron as a Signal Processing DeviceTao Hu, Zaid J. Towfic, Cengiz Pehlevan et al.
A neuron is a basic physiological and computational unit of the brain. While much is known about the physiological properties of a neuron, its computational role is poorly understood. Here we propose to view a neuron as a signal processing device that represents the incoming streaming data matrix as a sparse vector of synaptic weights scaled by an outgoing sparse activity vector. Formally, a neuron minimizes a cost function comprising a cumulative squared representation error and regularization terms. We derive an online algorithm that minimizes such cost function by alternating between the minimization with respect to activity and with respect to synaptic weights. The steps of this algorithm reproduce well-known physiological properties of a neuron, such as weighted summation and leaky integration of synaptic inputs, as well as an Oja-like, but parameter-free, synaptic learning rule. Our theoretical framework makes several predictions, some of which can be verified by the existing data, others require further experiments. Such framework should allow modeling the function of neuronal circuits without necessarily measuring all the microscopic biophysical parameters, as well as facilitate the design of neuromorphic electronics.
1.2NCOct 13, 2012
Online computation of sparse representations of time varying stimuli using a biologically motivated neural networkTao Hu, Dmitri B. Chklovskii
Natural stimuli are highly redundant, possessing significant spatial and temporal correlations. While sparse coding has been proposed as an efficient strategy employed by neural systems to encode sensory stimuli, the underlying mechanisms are still not well understood. Most previous approaches model the neural dynamics by the sparse representation dictionary itself and compute the representation coefficients offline. In reality, faced with the challenge of constantly changing stimuli, neurons must compute the sparse representations dynamically in an online fashion. Here, we describe a leaky linearized Bregman iteration (LLBI) algorithm which computes the time varying sparse representations using a biologically motivated network of leaky rectifying neurons. Compared to previous attempt of dynamic sparse coding, LLBI exploits the temporal correlation of stimuli and demonstrate better performance both in representation error and the smoothness of temporal evolution of sparse coefficients.
6.2NEOct 4, 2012
A network of spiking neurons for computing sparse representations in an energy efficient wayTao Hu, Alexander Genkin, Dmitri B. Chklovskii
Computing sparse redundant representations is an important problem both in applied mathematics and neuroscience. In many applications, this problem must be solved in an energy efficient way. Here, we propose a hybrid distributed algorithm (HDA), which solves this problem on a network of simple nodes communicating via low-bandwidth channels. HDA nodes perform both gradient-descent-like steps on analog internal variables and coordinate-descent-like steps via quantized external variables communicated to each other. Interestingly, such operation is equivalent to a network of integrate-and-fire neurons, suggesting that HDA may serve as a model of neural computation. We show that the numerical performance of HDA is on par with existing algorithms. In the asymptotic regime the representation error of HDA decays with time, t, as 1/t. HDA is stable against time-varying noise, specifically, the representation error decays as 1/sqrt(t) for Gaussian white noise.
4.0CVOct 1, 2012
Super-resolution using Sparse Representations over Learned Dictionaries: Reconstruction of Brain Structure using Electron MicroscopyTao Hu, Juan Nunez-Iglesias, Shiv Vitaladevuni et al.
A central problem in neuroscience is reconstructing neuronal circuits on the synapse level. Due to a wide range of scales in brain architecture such reconstruction requires imaging that is both high-resolution and high-throughput. Existing electron microscopy (EM) techniques possess required resolution in the lateral plane and either high-throughput or high depth resolution but not both. Here, we exploit recent advances in unsupervised learning and signal processing to obtain high depth-resolution EM images computationally without sacrificing throughput. First, we show that the brain tissue can be represented as a sparse linear combination of localized basis functions that are learned using high-resolution datasets. We then develop compressive sensing-inspired techniques that can reconstruct the brain tissue from very few (typically 5) tomographic views of each section. This enables tracing of neuronal processes and, hence, high throughput reconstruction of neural circuits on the level of individual synapses.