Elaine Lau

Stephen Obadinma, Faiza Khan Khattak, Shirley Wang et al. · utoronto

Building Agent Assistants that can help improve customer service support requires inputs from industry users and their customers, as well as knowledge about state-of-the-art Natural Language Processing (NLP) technology. We combine expertise from academia and industry to bridge the gap and build task/domain-specific Neural Agent Assistants (NAA) with three high-level components for: (1) Intent Identification, (2) Context Retrieval, and (3) Response Generation. In this paper, we outline the pipeline of the NAA's core system and also present three case studies in which three industry partners successfully adapt the framework to find solutions to their unique challenges. Our findings suggest that a collaborative process is instrumental in spurring the development of emerging NLP models for Conversational AI tasks in industry. The full reference implementation code and results are available at \url{https://github.com/VectorInstitute/NAA}

Elaine Lau, Markus Dücker, Ronak Chaudhary et al. · mit

Existing AI benchmarks lack the fidelity to assess economically meaningful progress on professional workflows. To evaluate frontier AI agents in a high-value, labor-intensive profession, we introduce BankerToolBench (BTB): an open-source benchmark of end-to-end analytical workflows routinely performed by junior investment bankers. To develop an ecologically valid benchmark grounded in representative work environments, we collaborated with 502 investment bankers from leading firms. BTB requires agents to execute senior banker requests by navigating data rooms, using industry tools (market data platform, SEC filings database), and generating multi-file deliverables--including Excel financial models, PowerPoint pitch decks, and PDF/Word reports. Completing a BTB task takes bankers up to 21 hours, underscoring the economic stakes of successfully delegating this work to AI. BTB enables automated evaluation of any LLM or agent, scoring deliverables against 100+ rubric criteria defined by veteran investment bankers to capture stakeholder utility. Testing 9 frontier models, we find that even the best-performing model (GPT-5.4) fails nearly half of the rubric criteria and bankers rate 0% of its outputs as client-ready. Our failure analysis reveals key obstacles (such as breakdowns in cross-artifact consistency) and improvement directions for agentic AI in high-stakes professional workflows.

Flemming Kondrup, Thomas Jiralerspong, Elaine Lau et al.

Mechanical ventilation is a key form of life support for patients with pulmonary impairment. Healthcare workers are required to continuously adjust ventilator settings for each patient, a challenging and time consuming task. Hence, it would be beneficial to develop an automated decision support tool to optimize ventilation treatment. We present DeepVent, a Conservative Q-Learning (CQL) based offline Deep Reinforcement Learning (DRL) agent that learns to predict the optimal ventilator parameters for a patient to promote 90 day survival. We design a clinically relevant intermediate reward that encourages continuous improvement of the patient vitals as well as addresses the challenge of sparse reward in RL. We find that DeepVent recommends ventilation parameters within safe ranges, as outlined in recent clinical trials. The CQL algorithm offers additional safety by mitigating the overestimation of the value estimates of out-of-distribution states/actions. We evaluate our agent using Fitted Q Evaluation (FQE) and demonstrate that it outperforms physicians from the MIMIC-III dataset.

Nikhil Vemgal, Elaine Lau, Doina Precup

Reinforcement Learning (RL) algorithms aim to learn an optimal policy by iteratively sampling actions to learn how to maximize the total expected return, $R(x)$. GFlowNets are a special class of algorithms designed to generate diverse candidates, $x$, from a discrete set, by learning a policy that approximates the proportional sampling of $R(x)$. GFlowNets exhibit improved mode discovery compared to conventional RL algorithms, which is very useful for applications such as drug discovery and combinatorial search. However, since GFlowNets are a relatively recent class of algorithms, many techniques which are useful in RL have not yet been associated with them. In this paper, we study the utilization of a replay buffer for GFlowNets. We explore empirically various replay buffer sampling techniques and assess the impact on the speed of mode discovery and the quality of the modes discovered. Our experimental results in the Hypergrid toy domain and a molecule synthesis environment demonstrate significant improvements in mode discovery when training with a replay buffer, compared to training only with trajectories generated on-policy.

Udari Madhushani Sehwag, Elaine Lau, Haniyeh Ehsani Oskouie et al.

Accelerating scientific discovery requires the identification of which experiments would yield the best outcomes before committing resources to costly physical validation. While existing benchmarks evaluate LLMs on scientific knowledge and reasoning, their ability to predict experimental outcomes - a task where AI could significantly exceed human capabilities - remains largely underexplored. We introduce SciPredict, a benchmark comprising 405 tasks derived from recent empirical studies in 33 specialized sub-fields of physics, biology, and chemistry. SciPredict addresses two critical questions: (a) can LLMs predict the outcome of scientific experiments with sufficient accuracy? and (b) can such predictions be reliably used in the scientific research process? Evaluations reveal fundamental limitations on both fronts. Model accuracies are 14-26% and human expert performance is $\approx$20%. Although some frontier models exceed human performance model accuracy is still far below what would enable reliable experimental guidance. Even within the limited performance, models fail to distinguish reliable predictions from unreliable ones, achieving only $\approx$20% accuracy regardless of their confidence or whether they judge outcomes as predictable without physical experimentation. Human experts, in contrast, demonstrate strong calibration: their accuracy increases from $\approx$5% to $\approx$80% as they deem outcomes more predictable without conducting the experiment. SciPredict establishes a rigorous framework demonstrating that superhuman performance in experimental science requires not just better predictions, but better awareness of prediction reliability. For reproducibility all our data and code are provided at https://github.com/scaleapi/scipredict

Elaine Lau, Nikhil Vemgal, Doina Precup et al.

Deep learning is emerging as an effective tool in drug discovery, with potential applications in both predictive and generative models. Generative Flow Networks (GFlowNets/GFNs) are a recently introduced method recognized for the ability to generate diverse candidates, in particular in small molecule generation tasks. In this work, we introduce double GFlowNets (DGFNs). Drawing inspiration from reinforcement learning and Double Deep Q-Learning, we introduce a target network used to sample trajectories, while updating the main network with these sampled trajectories. Empirical results confirm that DGFNs effectively enhance exploration in sparse reward domains and high-dimensional state spaces, both challenging aspects of de-novo design in drug discovery.

Mantas Mazeika, Alice Gatti, Cristina Menghini et al.

AIs have made rapid progress on research-oriented benchmarks of knowledge and reasoning, but it remains unclear how these gains translate into economic value and automation. To measure this, we introduce the Remote Labor Index (RLI), a broadly multi-sector benchmark comprising real-world, economically valuable projects designed to evaluate end-to-end agent performance in practical settings. AI agents perform near the floor on RLI, with the highest-performing agent achieving an automation rate of 2.5%. These results help ground discussions of AI automation in empirical evidence, setting a common basis for tracking AI impacts and enabling stakeholders to proactively navigate AI-driven labor automation.

Priyanshu Kumar, Elaine Lau, Saranya Vijayakumar et al.

For safety reasons, large language models (LLMs) are trained to refuse harmful user instructions, such as assisting dangerous activities. We study an open question in this work: does the desired safety refusal, typically enforced in chat contexts, generalize to non-chat and agentic use cases? Unlike chatbots, LLM agents equipped with general-purpose tools, such as web browsers and mobile devices, can directly influence the real world, making it even more crucial to refuse harmful instructions. In this work, we primarily focus on red-teaming browser agents, LLMs that manipulate information via web browsers. To this end, we introduce Browser Agent Red teaming Toolkit (BrowserART), a comprehensive test suite designed specifically for red-teaming browser agents. BrowserART is consist of 100 diverse browser-related harmful behaviors (including original behaviors and ones sourced from HarmBench [Mazeika et al., 2024] and AirBench 2024 [Zeng et al., 2024b]) across both synthetic and real websites. Our empirical study on state-of-the-art browser agents reveals that, while the backbone LLM refuses harmful instructions as a chatbot, the corresponding agent does not. Moreover, attack methods designed to jailbreak refusal-trained LLMs in the chat settings transfer effectively to browser agents. With human rewrites, GPT-4o and o1-preview-based browser agents attempted 98 and 63 harmful behaviors (out of 100), respectively. We publicly release BrowserART and call on LLM developers, policymakers, and agent developers to collaborate on improving agent safety

Anisha Gunjal, Anthony Wang, Elaine Lau et al.

Reinforcement Learning with Verifiable Rewards (RLVR) has proven effective for complex reasoning tasks with clear correctness signals such as math and coding. However, extending it to real-world reasoning tasks is challenging, as evaluation depends on nuanced, multi-criteria judgments rather than binary correctness. Instance-specific rubrics have recently been used in evaluation benchmarks to capture such judgments, but their potential as reward signals for on-policy post-training remains underexplored. We introduce $\textbf{Rubrics as Rewards}$ (RaR), an on-policy reinforcement learning method that extends RLVR beyond verifiable domains by using rubric-based feedback. Across both medical and science domains, we evaluate multiple strategies for aggregating rubric feedback into rewards. The best RaR variant achieves relative improvements of up to $31\%$ on HealthBench and $7\%$ on GPQA-Diamond over popular LLM-as-judge baselines that rely on direct Likert-based rewards. These results demonstrate that RaR-trained policies adapt well to diverse evaluation formats, performing strongly on both rubric-based and multiple-choice tasks. Moreover, we find that using rubrics as structured reward signals yields better alignment for smaller judges and reduces performance variance across judge scales.

Elaine Lau, Stephen Zhewen Lu, Ling Pan et al.

Generative Flow Networks (GFlowNets; GFNs) are a family of energy-based generative methods for combinatorial objects, capable of generating diverse and high-utility samples. However, consistently biasing GFNs towards producing high-utility samples is non-trivial. In this work, we leverage connections between GFNs and reinforcement learning (RL) and propose to combine the GFN policy with an action-value estimate, $Q$, to create greedier sampling policies which can be controlled by a mixing parameter. We show that several variants of the proposed method, QGFN, are able to improve on the number of high-reward samples generated in a variety of tasks without sacrificing diversity.

Vaskar Nath, Elaine Lau, Anisha Gunjal et al.

We study the process through which reasoning models trained with reinforcement learning on verifiable rewards (RLVR) can learn to solve new problems. We find that RLVR drives performance in two main ways: (1) by compressing pass@$k$ into pass@1 and (2) via "capability gain" in which models learn to solve new problems that they previously could not solve even at high $k$. We find that while capability gain exists across model scales, learning to solve new problems is primarily driven through self-distillation. We demonstrate these findings across model scales ranging from 0.5B to 72B parameters on >500,000 reasoning problems with prompts and verifiable final answers across math, science, and code domains. We further show that we can significantly improve pass@$k$ rates by leveraging natural language guidance for the model to consider within context while still requiring the model to derive a solution chain from scratch. Based of these insights, we derive $\text{Guide}$ -- a new class of online training algorithms. $\text{Guide}$ adaptively incorporates hints into the model's context on problems for which all rollouts were initially incorrect and adjusts the importance sampling ratio for the "off-policy" trajectories in order to optimize the policy for contexts in which the hints are no longer present. We describe variants of $\text{Guide}$ for GRPO and PPO and empirically show that Guide-GRPO on 7B and 32B parameter models improves generalization over its vanilla counterpart with up to 4$\%$ macro-average improvement across math benchmarks. We include careful ablations to analyze $\text{Guide}$'s components and theoretically analyze Guide's learning efficiency.

David Venuto, Elaine Lau, Doina Precup et al.

Reasoning about the future -- understanding how decisions in the present time affect outcomes in the future -- is one of the central challenges for reinforcement learning (RL), especially in highly-stochastic or partially observable environments. While predicting the future directly is hard, in this work we introduce a method that allows an agent to "look into the future" without explicitly predicting it. Namely, we propose to allow an agent, during its training on past experience, to observe what \emph{actually} happened in the future at that time, while enforcing an information bottleneck to avoid the agent overly relying on this privileged information. This gives our agent the opportunity to utilize rich and useful information about the future trajectory dynamics in addition to the present. Our method, Policy Gradients Incorporating the Future (PGIF), is easy to implement and versatile, being applicable to virtually any policy gradient algorithm. We apply our proposed method to a number of off-the-shelf RL algorithms and show that PGIF is able to achieve higher reward faster in a variety of online and offline RL domains, as well as sparse-reward and partially observable environments.