11.3AIJul 7
Finding H. pylori in the Fine Print: Evidence-Linked Multi-Agent Case Finding from Gastric Biopsy ReportsYufan Wang, Anit Kumar Sahu, Yan Fei Ng et al.
Data from Singapore indicated that about 31% of the population had evidence of Helicobacter pylori infection. Persistent H. pylori infection is associated with chronic active gastritis and peptic ulcer disease, and its eradication is key to gastric cancer prevention. However, evidence supporting \textit{H. pylori} positivity and H. pylori-associated gastritis may be distributed across heterogeneous coded and free-text report fields and may require contextual interpretation of assertion and negation, limiting keyword search, and making manual review difficult to scale. We conducted a retrospective pilot evaluation of the Nimblemind Multi-Agent System (nMAS), a field-name-driven, evidence-linked extraction workflow, using 54 de-identified gastric biopsy pathology reports from a large healthcare system in Singapore. Four clinician-scoped binary fields were evaluated: gastric/stomach biopsy, biopsy status, H. pylori positivity, and H. pylori-associated gastritis. Across 216 feature-case decisions, nMAS correctly classified 213, corresponding to 98.61% overall accuracy. A separately implemented UMA-style MiniMax M2.5 comparator produced similar aggregate and per-field classification metrics. Although predictive performance was similar, nMAS maintained unified report-level outputs with supporting source sentences; the demonstrated contribution is therefore workflow integration and traceability rather than predictive superiority. Under an illustrative, unmeasured scenario, reviewing 1,000 reports at five minutes per manual review versus five seconds per evidence-linked verification would reduce review time from 83.3 to 1.4 staff-hours, corresponding to 81.9 staff-hours and about USD~6,100 in potential staff-time value. Larger multi-institutional studies should evaluate evidence-span correctness, clinician verification time, and generalizability.
5.7HCJun 20
AI-Mediated Negotiation: Design Reflections and LessonsVeda Duddu, Jash Rajesh Parekh, Andy Mao et al.
Conversational AI promises a new kind of preparation for high-stakes workplace negotiations -- personalized, interactive, and capable of simulating realistic resistance. That promise is intuitive. We built Trucey, a theory-driven coaching system, to test it. The system encoded four assumptions: that articulation supports clarification, that personalization builds strategic competence, that chunked delivery reduces cognitive load, and that structured scaffolding removes metacognitive burden. A pre-registered experiment (N=267) and interviews (N=15) complicated each of them. Notably, the static handbook we included as a passive control outperformed both AI conditions on empowerment and usability. We reflect on why: each assumption encoded a specific model of how preparation unfolds, and the findings revealed that conversational AI imposes a linear execution model on a task that is fundamentally recursive. We identify an unexamined scope condition on established HAI design guidelines and close with a sequencing principle -- map before path, path before simulation -- for future AI coaching design.
11.2HCJun 17
A Taxonomy of Mental Health and Technology Needs for Alzheimer's and Dementia CaregiversKeran Wang, Drishti Goel, Jiayue Melissa Shi et al.
Family members caring for individuals with Alzheimer's disease and related dementias (AD/ADRD) provide the foundation of long-term care worldwide. In 2023, more than 11 million U.S. family and friends contributed 18 billion hours of unpaid care, often at the cost of their own physical and mental health. These informal caregivers -- also referred as the "invisible second patients" -- experience elevated rates of mental health problems. Yet research commonly reduces their complex psychosocial experiences to a single construct of caregiver burden, obscuring which specific needs are unmet or effectively supported. At the same time, digital and AI-enabled technologies are rapidly expanding, from smartphone apps and videoconferencing to sensor platforms and AI chatbots. However, the absence of shared frameworks across medicine, psychology, and technology research limits cumulative progress. This study introduces a Caregiver Mental Health and Technology Taxonomy that systematically links AD/ADRD caregiver needs with corresponding classes of technology-based interventions. Drawing from an interdisciplinary literature review and two qualitative studies with caregivers, the taxonomy identifies mismatches between caregiver priorities and existing technological support, highlights under-served domains such as relational strain and compassion fatigue, and proposes design directions for adaptive, responsive systems. The framework offers a shared vocabulary to guide clinicians, researchers, and technology designers in developing more person-centered and clinically grounded innovation in dementia care.