Ting Ma

Yuheng Qiu, Jingyi Luo, Chenfei Ye et al.

Deep learning has demonstrated remarkable success in high-throughput histopathology image analysis. However, the performance of learning-based models critically depends on the quality and size of annotations by expert pathologists, which is a resource-intensive and time-consuming process. To address the limitations of data scarcity and annotation burden, several methods have been proposed to synthesize paired histopathology data. Nevertheless, these frameworks typically still require annotation data, albeit in reduced quantities, to impose structural constraints during training. In this work, we present CHIS, a plug-in framework that guides the sampling trajectory of a pretrained diffusion model through two key stages: structural initialization at the start and textural modulation during generation. The initial noise state is refined by fusing the phase information from a prior mask with the amplitude of Gaussian noise in the frequency domain, yielding a structurally informed starting point. During the reverse diffusion process, we adaptively modulate both coarse-grained and fine-grained textures at different wavelet decomposition levels. This enables a diffusion model pretrained solely on unlabeled images to generate outputs that align with prior structural masks while preserving the reference tissue style. We conducted extensive experiments demonstrating the superiority of CHIS in generation fidelity and its substantial benefits for downstream segmentation tasks. Code is available at https://github.com/IBIL-Code/CHIS.

Ting Ma, Xiufeng Huang, Benlei Cui et al.

As large language models are increasingly deployed in real-world systems, safety failures can still lead to harmful outputs and dangerous misuse. We argue that the essence of safety is adversarial: many failures arise not from natural inputs alone, but from strategic attempts to evade model policies and safeguards. However, existing general-purpose model development largely overlook this adversarial nature, and often remain insufficient for realistic safety scenarios involving planning, tool use, and multi-step reasoning, causing measured safety performance to overestimate real deployment robustness. To address this gap, we present Yuvion LLM, a large language model built for adversarially robust content safety and broader AI safety. Yuvion LLM treats adversarial robustness and agentic capability as first-class objectives. Its pipeline combines adversarially aware data construction, knowledge-enhanced continued pretraining, and policy-grounded multi-task safety post-training, including risk-aware supervised fine-tuning and reinforcement learning-based policy optimization, together with safety-aware agentic reinforcement learning for tool use and multi-step reasoning in complex safety scenarios. We further introduce the Yuvion LLM RiskEval (YLRE), a collection of 93 benchmarks across four evaluation categories, covering diverse open and internal evaluations with a focus on safety, adversarial robustness, and real-world capability requirements. Across these evaluations, Yuvion LLM demonstrates clear advantages on safety-focused benchmarks and particularly strong robustness under adversarial conditions, while maintaining solid overall capability. Notably, Yuvion-8B outperforms most state-of-the-art baselines, including substantially larger models such as GPT-5.4 and Qwen3-MAX, on several safety tasks.