Wei Li

Wei Li, Jingyang Zhang, Guoan Wang et al.

Universal segmentation models exhibit significant potential for diverse tasks involving different imaging modalities and segmentation objectives. Task-Incremental Learning provides a privacy-preserving approach to continually evolve a universal model on tasks from sequentially-arriving medical departments. However, training the model solely on the incoming task induces forgetting on past tasks, since consecutive tasks exhibit concurrent shifts in image appearance and segmentation objective. To address this problem, we propose a novel Coupled Comprehensive Generative Replay (C^2GR) framework that simultaneously synthesizes image-mask pairs of previous tasks to mitigate forgetting under concurrent appearance and objective shifts. This requires preserving image-mask correspondence for structure-realistic generation and bridging asynchronous optimization of the generator and segmentor for segmentation-oriented generation. Specifically, we propose a Bayesian Joint Diffusion (BJD) method that formulates the correspondence as conditional distributions optimized via conditional denoising. Furthermore, we develop a Relation-aware Unified Prompt Synchronization (RUPS) scheme to simultaneously modulate the generator and segmentor via a shared task-relation-aware prompt for synchronizing their optimization. Experiments on 20 tasks spanning diverse modalities and objectives demonstrate that C^2GR exhibits only a 2.44% drop in overall performance compared to joint training with all task data, effectively alleviating forgetting from the concurrent shifts. Our code will be made publicly available at https://github.com/mar-cry/C2GR.

Zijian Fu, Xiangyang Chu, Mengshi Qi et al.

Instruction-conditioned trajectory prediction is an emerging problem in autonomous driving, where a model predicts the future ego trajectory not only from visual scene context and historical motion, but also from a natural-language maneuver instruction. This paper presents our submission to the doScenes Instructed Driving Challenge, built upon OmniDrive, a vision-language-action driving agent with 3D perception, reasoning, and planning capabilities. We adapt OmniDrive to the doScenes setting by training it on instruction-annotated nuScenes scenes and generating a 6-second ego trajectory represented by 12 future waypoints. To improve multi-view visual grounding, we further introduce a DVPE-style divided-view perception module into the OmniDrive perception head. Instead of attending globally to all camera features, the proposed module groups query features and image tokens into divided local view spaces and performs visibility-aware cross-attention within each view. This design reduces irrelevant cross-view interference and helps the model better align language instructions with local driving-relevant visual evidence. The code is publicly available at: https://github.com/feel12348/doscenes-omnidrive.

Qihan Chen, Wei Li, Meng Qin et al.

We develop a spectral theory for \emph{normalized corrected GNN propagation}. The object of study is the symmetric normalized adjacency with its degree-stationary component removed, matching the normalization used by standard GCN-style models while isolating the stationary direction most directly tied to oversmoothing. The central theoretical question is whether this corrected normalized operator preserves class-discriminative signal after many propagation layers. Our main result is a high-probability exact-recovery theorem for the binary Contextual Stochastic Block Model after \(k=O(\log n)\) propagation steps in the dense polylogarithmic regime \(p\ge C\log^B n/n\), for any fixed \(B>4\), under explicit graph-signal and feature-SNR conditions. We also establish a multi-class partial recovery theorem showing contraction toward class centers for most nodes. Synthetic and real node-classification experiments are included as empirical checks of the theory's predicted dependence on depth, graph signal, and feature noise.

Qizhi Pei, Zhimeng Zhou, Yi Duan et al.

We present BioMatrix, the first multimodal foundation model that natively integrates sequences, structures, and natural language for both molecules and proteins within a single decoder-only architecture. Existing biological foundation models pursue native multimodality and broad entity coverage separately: those that fuse multiple modalities under a shared objective remain confined to a single entity type, while those spanning multiple entity types either omit explicit structural modeling or rely on adapter-based designs in which the model cannot natively generate the very modalities it can read. BioMatrix closes this gap by mapping molecular sequences (supporting both SMILES and SELFIES notations), molecular structures, protein sequences, protein structures, and natural language into a shared discrete token space through a unified tokenization scheme, so that all modalities are consumed and produced uniformly under a single next-token prediction objective -- without external encoders, projection adapters, or modality-specific output heads. Built upon the Qwen3 language model (1.7B and 4B), BioMatrix is continually pretrained on 304.4 billion tokens spanning general and domain-specific text, sequence and structure views of molecules and proteins, and cross-modal corpora that interleave biomolecular entities with scientific text and link distinct entities through molecule-protein and protein-protein interaction data. After tuning on a comprehensive suite of downstream applications covering 80 tasks across 6 categories -- encompassing single-entity and multi-entity understanding and generation tasks across and within modalities -- BioMatrix achieves state-of-the-art or competitive performance on 77 out of 80 tasks, demonstrating that a single, natively multimodal generalist model can effectively match or surpass specialized approaches across a wide range of biological tasks.