Zhan Jin

Zhan Jin, Yu Luo, Yizhou Zhang et al.

Conventional pixel-wise loss functions fail to enforce topological constraints in coronary vessel segmentation, producing fragmented vascular trees despite high pixel-level accuracy. We present ARIADNE, a two-stage framework coupling preference-aligned perception with RL-based diagnostic reasoning for topologically coherent stenosis detection. The perception module employs DPO to fine-tune the Sa2VA vision-language foundation model using Betti number constraints as preference signals, aligning the policy toward geometrically complete vessel structures rather than pixel-wise overlap metrics. The reasoning module formulates stenosis localization as a Markov Decision Process with an explicit rejection mechanism that autonomously defers ambiguous anatomical candidates such as bifurcations and vessel crossings, shifting from coverage maximization to reliability optimization. On 1,400 clinical angiograms, ARIADNE achieves state-of-the-art centerline Dice of 0.838, reduces false positives by 41% compared to geometric baselines. External validation on multi-center benchmarks ARCADE and XCAD confirms generalization across acquisition protocols. This represents the first application of DPO for topological alignment in medical imaging, demonstrating that preference-based learning over structural constraints mitigates topological violations while maintaining diagnostic sensitivity in interventional cardiology workflows.

Jiarong Du, Zhan Jin, Peijun Yang et al.

Audio-visual speech enhancement (AVSE) is a task that uses visual auxiliary information to extract a target speaker's speech from mixed audio. In real-world scenarios, there often exist complex acoustic environments, accompanied by various interfering sounds and reverberation. Most previous methods struggle to cope with such complex conditions, resulting in poor perceptual quality of the extracted speech. In this paper, we propose an effective AVSE system that performs well in complex acoustic environments. Specifically, we design a "separation before dereverberation" pipeline that can be extended to other AVSE networks. The 4th COGMHEAR Audio-Visual Speech Enhancement Challenge (AVSEC) aims to explore new approaches to speech processing in multimodal complex environments. We validated the performance of our system in AVSEC-4: we achieved excellent results in the three objective metrics on the competition leaderboard, and ultimately secured first place in the human subjective listening test.

Rohan Kadekodi, Zhan Jin, Keisuke Kamahori et al. · uw

The deployment of Large Language Models (LLMs) as agentic orchestrators has revolutionized task automation, but the need for privacy-preserving, cost-effective solutions demands on-device inference capabilities. However, local LLMs consistently underperform compared to frontier models in tool calling scenarios, struggling with both tool selection from large tool sets and accurate argument generation for complex parameter structures. We introduce a methodology that disaggregates a tool-calling task into two distinct subtasks: tool selection and argument generation. We propose "decoupled fine-tuning", a novel post-training approach that employs LoRA fine-tuning to create dedicated LoRA adapters for tool selection and tool-specific argument generation using separate loss masking for each of the subtasks. Furthermore, we present AgentFlux, an inference framework that leverages the LoRA adapters created using decoupled fine-tuning to perform efficient agent orchestration with the help of local models on end-user devices. AgentFlux decomposes the tool-call generation step into tool selection and argument generation, and dynamically loads the corresponding LoRA adapters to generate tool calls. Additionally, AgentFlux implements hierarchical orchestration to restrict the number of tools required for tool selection. Our experiments on the MCP-Bench benchmark demonstrate that the Qwen-2.5-7B model trained using decoupled fine-tuning improves the tool calling accuracy of the base model by 46%, and outperforms other local reasoning, non-reasoning and fine-tuned models of similar size in all cases, and models that are 2x larger, in most cases.