13.0CLJul 2, 2025
Clinical NLP with Attention-Based Deep Learning for Multi-Disease PredictionTing Xu, Xiaoxiao Deng, Xiandong Meng et al.
This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling for information extraction and multi-label disease prediction. The study is conducted on the MIMIC-IV dataset. A Transformer-based architecture is used to perform representation learning over clinical text. Multi-layer self-attention mechanisms are employed to capture key medical entities and their contextual relationships. A Sigmoid-based multi-label classifier is then applied to predict multiple disease labels. The model incorporates a context-aware semantic alignment mechanism, enhancing its representational capacity in typical medical scenarios such as label co-occurrence and sparse information. To comprehensively evaluate model performance, a series of experiments were conducted, including baseline comparisons, hyperparameter sensitivity analysis, data perturbation studies, and noise injection tests. Results demonstrate that the proposed method consistently outperforms representative existing approaches across multiple performance metrics. The model maintains strong generalization under varying data scales, interference levels, and model depth configurations. The framework developed in this study offers an efficient algorithmic foundation for processing real-world clinical texts and presents practical significance for multi-label medical text modeling tasks.
16.9LGAug 20, 2025
Structure-Aware Temporal Modeling for Chronic Disease Progression PredictionJiacheng Hu, Bo Zhang, Ting Xu et al.
This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural perception and temporal modeling. The method leverages graph neural networks to model the structural relationships among multimodal clinical symptoms and introduces graph-based representations to capture semantic dependencies between symptoms. It also incorporates a Transformer architecture to model dynamic temporal features during disease progression. To fuse structural and temporal information, a structure-aware gating mechanism is designed to dynamically adjust the fusion weights between structural encodings and temporal features, enhancing the model's ability to identify key progression stages. To improve classification accuracy and stability, the framework includes a multi-component modeling pipeline, consisting of a graph construction module, a temporal encoding module, and a prediction output layer. The model is evaluated on real-world longitudinal Parkinson's disease data. The experiments involve comparisons with mainstream models, sensitivity analysis of hyperparameters, and graph connection density control. Results show that the proposed method outperforms existing approaches in AUC, RMSE, and IPW-F1 metrics. It effectively distinguishes progression stages and improves the model's ability to capture personalized symptom trajectories. The overall framework demonstrates strong generalization and structural scalability, providing reliable support for intelligent modeling of chronic progressive diseases such as Parkinson's disease.
MyGO Multiplex CoT: A Method for Self-Reflection in Large Language Models via Double Chain of Thought ThinkingShihao Ji, Zihui Song, Fucheng Zhong et al.
Recent advancements in large language models (LLMs) have demonstrated their impressive abilities in various reasoning and decision-making tasks. However, the quality and coherence of the reasoning process can still benefit from enhanced introspection and self-reflection. In this paper, we introduce Multiplex CoT (Chain of Thought), a method that enables LLMs to simulate a form of self-review while reasoning, by initiating double Chain of Thought (CoT) thinking. Multiplex CoT leverages the power of iterative reasoning, where the model generates an initial chain of thought and subsequently critiques and refines this reasoning with a second round of thought generation. This recursive approach allows for more coherent, logical, and robust answers, improving the overall decision-making process. We demonstrate how this method can be effectively implemented using simple prompt engineering in existing LLM architectures, achieving an effect similar to that of the Learning-Refinement Model (LRM) without the need for additional training. Additionally, we present a practical guide for implementing the method in Google Colab, enabling easy integration into real-world applications.
OpenGrok: Enhancing SNS Data Processing with Distilled Knowledge and Mask-like MechanismsLumen AI, Zaozhuang No. 28 Middle School, Shihao Ji et al.
This report details Lumen Labs' novel approach to processing Social Networking Service (SNS) data. We leverage knowledge distillation, specifically a simple distillation method inspired by DeepSeek-R1's CoT acquisition, combined with prompt hacking, to extract valuable training data from the Grok model. This data is then used to fine-tune a Phi-3-mini model, augmented with a mask-like mechanism specifically designed for handling the nuances of SNS data. Our method demonstrates state-of-the-art (SOTA) performance on several SNS data processing tasks, outperforming existing models like Grok, Phi-3, and GPT-4. We provide a comprehensive analysis of our approach, including mathematical formulations, engineering details, ablation studies, and comparative evaluations.
11.5LGJun 13, 2024
Research on Early Warning Model of Cardiovascular Disease Based on Computer Deep LearningYuxiang Hu, Jinxin Hu, Ting Xu et al.
This project intends to study a cardiovascular disease risk early warning model based on one-dimensional convolutional neural networks. First, the missing values of 13 physiological and symptom indicators such as patient age, blood glucose, cholesterol, and chest pain were filled and Z-score was standardized. The convolutional neural network is converted into a 2D matrix, the convolution function of 1,3, and 5 is used for the first-order convolution operation, and the Max Pooling algorithm is adopted for dimension reduction. Set the learning rate and output rate. It is optimized by the Adam algorithm. The result of classification is output by a soft classifier. This study was conducted based on Statlog in the UCI database and heart disease database respectively. The empirical data indicate that the forecasting precision of this technique has been enhanced by 11.2%, relative to conventional approaches, while there is a significant improvement in the logarithmic curve fitting. The efficacy and applicability of the novel approach are corroborated through the examination employing a one-dimensional convolutional neural network.