Wagner Meira

Jose Geraldo Fernandes, Luiz Facury, Pedro Robles Dutenhefner et al.

Self-supervised learning in healthcare has largely relied on invariance-based objectives, which maximize similarity between different views of the same patient. While effective for static anatomy, this paradigm is fundamentally misaligned with clinical diagnosis, as it mathematically compels the model to suppress the transient pathological changes it is intended to detect. We propose a shift towards Action-Conditioned World Models that learn to simulate the dynamics of disease progression, or Event-Conditioned. Adapting the LeJEPA framework to physiological time-series, we define pathology not as a static label, but as a transition vector acting on a patient's latent state. By predicting the future electrophysiological state of the heart given a disease onset, our model explicitly disentangles stable anatomical features from dynamic pathological forces. Evaluated on the MIMIC-IV-ECG dataset, our approach outperforms fully supervised baselines on the critical triage task. Crucially, we demonstrate superior sample efficiency: in low-resource regimes, our world model outperforms supervised learning by over 0.05 AUROC. These results suggest that modeling biological dynamics provides a dense supervision signal that is far more robust than static classification. Source code is available at https://github.com/cljosegfer/lesaude-dynamics

Marcelo Sartori Locatelli, Matheus Prado Miranda, Igor Joaquim da Silva Costa et al.

The Exame Nacional do Ensino Médio (ENEM) is a pivotal test for Brazilian students, required for admission to a significant number of universities in Brazil. The test consists of four objective high-school level tests on Math, Humanities, Natural Sciences and Languages, and one writing essay. Students' answers to the test and to the accompanying socioeconomic status questionnaire are made public every year (albeit anonymized) due to transparency policies from the Brazilian Government. In the context of large language models (LLMs), these data lend themselves nicely to comparing different groups of humans with AI, as we can have access to human and machine answer distributions. We leverage these characteristics of the ENEM dataset and compare GPT-3.5 and 4, and MariTalk, a model trained using Portuguese data, to humans, aiming to ascertain how their answers relate to real societal groups and what that may reveal about the model biases. We divide the human groups by using socioeconomic status (SES), and compare their answer distribution with LLMs for each question and for the essay. We find no significant biases when comparing LLM performance to humans on the multiple-choice Brazilian Portuguese tests, as the distance between model and human answers is mostly determined by the human accuracy. A similar conclusion is found by looking at the generated text as, when analyzing the essays, we observe that human and LLM essays differ in a few key factors, one being the choice of words where model essays were easily separable from human ones. The texts also differ syntactically, with LLM generated essays exhibiting, on average, smaller sentences and less thought units, among other differences. These results suggest that, for Brazilian Portuguese in the ENEM context, LLM outputs represent no group of humans, being significantly different from the answers from Brazilian students across all tests.

Jose Geraldo Fernandes, Luiz Facury de Souza, Pedro Robles Dutenhefner et al.

Deep learning models have shown high accuracy in classifying electrocardiograms (ECGs), but their black box nature hinders clinical adoption due to a lack of trust and interpretability. To address this, we propose a novel three-stage training paradigm that transfers knowledge from multimodal clinical data (laboratory exams, vitals, biometrics) into a powerful, yet unimodal, ECG encoder. We employ a self-supervised, joint-embedding pre-training stage to create an ECG representation that is enriched with contextual clinical information, while only requiring the ECG signal at inference time. Furthermore, as an indirect way to explain the model's output we train it to also predict associated laboratory abnormalities directly from the ECG embedding. Evaluated on the MIMIC-IV-ECG dataset, our model outperforms a standard signal-only baseline in multi-label diagnosis classification and successfully bridges a substantial portion of the performance gap to a fully multimodal model that requires all data at inference. Our work demonstrates a practical and effective method for creating more accurate and trustworthy ECG classification models. By converting abstract predictions into physiologically grounded \emph{explanations}, our approach offers a promising path toward the safer integration of AI into clinical workflows.

Marcelo Sartori Locatelli, Wenchao Dong, Pedro Loures Alzamora et al.

Climate misinformation continues to erode support for climate action, a challenge that is especially acute in the Global South, where high climate vulnerability intersects with development pressures. In rapidly evolving digital ecosystems, misinformation adapts to platform incentives, shifting from overt rejection of climate science toward more subtle narratives that contest proposed solutions. This study integrates large-scale platform data with qualitative content analysis to examine how information systems shape contemporary climate discourse. Using a dataset of 226,775 climate-related YouTube videos from Brazil (2019-2025), we identify two dominant misinformation strategies: traditional denial that disputes scientific evidence and an emerging "new denial" that accepts climate change while undermining mitigation and adaptation policies. We find a pronounced transition to solution-focused narratives that target renewable energy, climate governance, and environmental advocates. New denial content is produced by a wider array of actors, attracts higher engagement, and employs more sophisticated persuasive techniques. These patterns disproportionately affect regions already facing structural inequities and bring broader concerns about platform accountability in unequal information environments and suggest the need for governance approaches capable of addressing new denial, a rapidly adapting form of harmful content that often evades existing moderation policies.

Flávio Soriano, Victoria F. Mello, Pedro B. Rigueira et al.

Analyses of legislative behavior often rely on voting records, overlooking the rich semantic and rhetorical content of political speech. In this paper, we ask three complementary questions about parliamentary discourse: how things are said, what is being said, and who is speaking in discursively similar ways. To answer these questions, we introduce a scalable and generalizable computational framework that combines diachronic stylometric analysis, contextual topic modeling, and semantic clustering of deputies' speeches. We apply this framework to a large-scale case study of the Brazilian Chamber of Deputies, using a corpus of over 450,000 speeches from 2003 to 2025. Our results show a long-term stylistic shift toward shorter and more direct speeches, a legislative agenda that reorients sharply in response to national crises, and a granular map of discursive alignments in which regional and gender identities often prove more salient than formal party affiliation. More broadly, this work offers a robust methodology for analyzing parliamentary discourse as a multidimensional phenomenon that complements traditional vote-based approaches.

Ian Miles, Mayumi Wakimoto, Wagner Meira et al.

This review explores the integration of Artificial Intelligence into Horizon Scanning, focusing on identifying and responding to emerging threats and opportunities linked to Infectious Diseases. We examine how AI tools can enhance signal detection, data monitoring, scenario analysis, and decision support. We also address the risks associated with AI adoption and propose strategies for effective implementation and governance. The findings contribute to the growing body of Foresight literature by demonstrating the potential and limitations of AI in Public Health preparedness.

Arthur Buzelin, Pedro Robles Dutenhefner, Turi Rezende et al.

Cardiovascular diseases remain the leading cause of global mortality, emphasizing the critical need for efficient diagnostic tools such as electrocardiograms (ECGs). Recent advancements in deep learning, particularly transformers, have revolutionized ECG analysis by capturing detailed waveform features as well as global rhythm patterns. However, traditional transformers struggle to effectively capture local morphological features that are critical for accurate ECG interpretation. We propose a novel Local-Global Attention ECG model (LGA-ECG) to address this limitation, integrating convolutional inductive biases with global self-attention mechanisms. Our approach extracts queries by averaging embeddings obtained from overlapping convolutional windows, enabling fine-grained morphological analysis, while simultaneously modeling global context through attention to keys and values derived from the entire sequence. Experiments conducted on the CODE-15 dataset demonstrate that LGA-ECG outperforms state-of-the-art models and ablation studies validate the effectiveness of the local-global attention strategy. By capturing the hierarchical temporal dependencies and morphological patterns in ECG signals, this new design showcases its potential for clinical deployment with robust automated ECG classification.

Antônio H. Ribeiro, Manoel Horta Ribeiro, Gabriela M. M. Paixão et al.

The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has recently achieved striking success in a variety of task and there are great expectations on how it might improve clinical practice. Here we present a DNN model trained in a dataset with more than 2 million labeled exams analyzed by the Telehealth Network of Minas Gerais and collected under the scope of the CODE (Clinical Outcomes in Digital Electrocardiology) study. The DNN outperform cardiology resident medical doctors in recognizing 6 types of abnormalities in 12-lead ECG recordings, with F1 scores above 80% and specificity over 99%. These results indicate ECG analysis based on DNNs, previously studied in a single-lead setup, generalizes well to 12-lead exams, taking the technology closer to the standard clinical practice.

Antônio H. Ribeiro, Manoel Horta Ribeiro, Gabriela Paixão et al.

We present a model for predicting electrocardiogram (ECG) abnormalities in short-duration 12-lead ECG signals which outperformed medical doctors on the 4th year of their cardiology residency. Such exams can provide a full evaluation of heart activity and have not been studied in previous end-to-end machine learning papers. Using the database of a large telehealth network, we built a novel dataset with more than 2 million ECG tracings, orders of magnitude larger than those used in previous studies. Moreover, our dataset is more realistic, as it consist of 12-lead ECGs recorded during standard in-clinics exams. Using this data, we trained a residual neural network with 9 convolutional layers to map 7 to 10 second ECG signals to 6 classes of ECG abnormalities. Future work should extend these results to cover a large range of ECG abnormalities, which could improve the accessibility of this diagnostic tool and avoid wrong diagnosis from medical doctors.

Carlos H. C. Teixeira, Leonardo Cotta, Bruno Ribeiro et al.

In this work we propose R-GPM, a parallel computing framework for graph pattern mining (GPM) through a user-defined subgraph relation. More specifically, we enable the computation of statistics of patterns through their subgraph classes, generalizing traditional GPM methods. R-GPM provides efficient estimators for these statistics by employing a MCMC sampling algorithm combined with several optimizations. We provide both theoretical guarantees and empirical evaluations of our estimators in application scenarios such as stochastic optimization of deep high-order graph neural network models and pattern (motif) counting. We also propose and evaluate optimizations that enable improvements of our estimators accuracy, while reducing their computational costs in up to 3-orders-of-magnitude. Finally,we show that R-GPM is scalable, providing near-linear speedups on 44 cores in all of our tests.

Josemar Alves Caetano, Gabriel Magno, Evandro Cunha et al.

WhatsApp is, as of 2018, a significant component of the global information and communication infrastructure, especially in developing countries. However, probably due to its strong end-to-end encryption, WhatsApp became an attractive place for the dissemination of misinformation, extremism and other forms of undesirable behavior. In this paper, we investigate the public perception of WhatsApp through the lens of media. We analyze two large datasets of news and show the kind of content that is being associated with WhatsApp in different regions of the world and over time. Our analyses include the examination of named entities, general vocabulary, and topics addressed in news articles that mention WhatsApp, as well as the polarity of these texts. Among other results, we demonstrate that the vocabulary and topics around the term "whatsapp" in the media have been changing over the years and in 2018 concentrate on matters related to misinformation, politics and criminal scams. More generally, our findings are useful to understand the impact that tools like WhatsApp play in the contemporary society and how they are seen by the communities themselves.

Manoel Horta Ribeiro, Bruno Teixeira, Antônio Otávio Fernandes et al.

Many of the state-of-the-art algorithms for gesture recognition are based on Conditional Random Fields (CRFs). Successful approaches, such as the Latent-Dynamic CRFs, extend the CRF by incorporating latent variables, whose values are mapped to the values of the labels. In this paper we propose a novel methodology to set the latent values according to the gesture complexity. We use an heuristic that iterates through the samples associated with each label value, stimating their complexity. We then use it to assign the latent values to the label values. We evaluate our method on the task of recognizing human gestures from video streams. The experiments were performed in binary datasets, generated by grouping different labels. Our results demonstrate that our approach outperforms the arbitrary one in many cases, increasing the accuracy by up to 10%.

Roberto C. S. N. P. Souza, Denise E. F de Brito, Renato M. Assunção et al.

Exploiting the large amount of available data for addressing relevant social problems has been one of the key challenges in data mining. Such efforts have been recently named "data science for social good" and attracted the attention of several researchers and institutions. We give a contribution in this objective in this paper considering a difficult public health problem, the timely monitoring of dengue epidemics in small geographical areas. We develop a generative simple yet effective model to connect the fluctuations of disease cases and disease-related Twitter posts. We considered a hidden Markov process driving both, the fluctuations in dengue reported cases and the tweets issued in each region. We add a stable but random source of tweets to represent the posts when no disease cases are recorded. The model is learned through a Markov chain Monte Carlo algorithm that produces the posterior distribution of the relevant parameters. Using data from a significant number of large Brazilian towns, we demonstrate empirically that our model is able to predict well the next weeks of the disease counts using the tweets and disease cases jointly.

George Teodoro, Eduardo Valle, Nathan Mariano et al.

Similarity search in high-dimentional spaces is a pivotal operation found a variety of database applications. Recently, there has been an increase interest in similarity search for online content-based multimedia services. Those services, however, introduce new challenges with respect to the very large volumes of data that have to be indexed/searched, and the need to minimize response times observed by the end-users. Additionally, those users dynamically interact with the systems creating fluctuating query request rates, requiring the search algorithm to adapt in order to better utilize the underline hardware to reduce response times. In order to address these challenges, we introduce hypercurves, a flexible framework for answering approximate k-nearest neighbor (kNN) queries for very large multimedia databases, aiming at online content-based multimedia services. Hypercurves executes on hybrid CPU--GPU environments, and is able to employ those devices cooperatively to support massive query request rates. In order to keep the response times optimal as the request rates vary, it employs a novel dynamic scheduler to partition the work between CPU and GPU. Hypercurves was throughly evaluated using a large database of multimedia descriptors. Its cooperative CPU--GPU execution achieved performance improvements of up to 30x when compared to the single CPU-core version. The dynamic work partition mechanism reduces the observed query response times in about 50% when compared to the best static CPU--GPU task partition configuration. In addition, Hypercurves achieves superlinear scalability in distributed (multi-node) executions, while keeping a high guarantee of equivalence with its sequential version --- thanks to the proof of probabilistic equivalence, which supported its aggressive parallelization design.