Xingyao Zhang

Xiangru Tang, Anni Zou, Zhuosheng Zhang et al.

Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and reasoning over specialized knowledge. To address these issues, we propose MedAgents, a novel multi-disciplinary collaboration framework for the medical domain. MedAgents leverages LLM-based agents in a role-playing setting that participate in a collaborative multi-round discussion, thereby enhancing LLM proficiency and reasoning capabilities. This training-free framework encompasses five critical steps: gathering domain experts, proposing individual analyses, summarising these analyses into a report, iterating over discussions until a consensus is reached, and ultimately making a decision. Our work focuses on the zero-shot setting, which is applicable in real-world scenarios. Experimental results on nine datasets (MedQA, MedMCQA, PubMedQA, and six subtasks from MMLU) establish that our proposed MedAgents framework excels at mining and harnessing the medical expertise within LLMs, as well as extending its reasoning abilities. Our code can be found at https://github.com/gersteinlab/MedAgents.

Joo Hyung Lee, Wonpyo Park, Nicole Mitchell et al. · mila

This paper introduces JaxPruner, an open-source JAX-based pruning and sparse training library for machine learning research. JaxPruner aims to accelerate research on sparse neural networks by providing concise implementations of popular pruning and sparse training algorithms with minimal memory and latency overhead. Algorithms implemented in JaxPruner use a common API and work seamlessly with the popular optimization library Optax, which, in turn, enables easy integration with existing JAX based libraries. We demonstrate this ease of integration by providing examples in four different codebases: Scenic, t5x, Dopamine and FedJAX and provide baseline experiments on popular benchmarks.

Junzhe Zhang, Huixuan Zhang, Guirong Wang et al.

With the rapid advancement of multimodal large language models (MLLMs), models have demonstrated increasingly powerful multimodal capabilities. However, whether MLLMs trained through statistical learning can truly understand the causal relationships underlying the real world remains a key research question. In recent years, numerous multimodal causal reasoning datasets have been proposed. Nevertheless, these datasets are either limited in scale or constructed from synthetic images and videos, cartoon-based content, or other non-realistic multimodal sources. To address these limitations, we collect real-world videos and construct DMC-CF-Static, a large-scale benchmark for multimodal causal counterfactual reasoning. Furthermore, to mitigate issues such as data contamination in traditional static evaluation, we represent causal events using causal graphs and propose the Dynamic Graph Intervention (DGI) framework to build the dynamic evaluation benchmark DMC-CF-Dynamic from DMC-CF-Static. Experimental results on the overall DMC-CF, which includes both static and dynamic evaluation benchmarks, demonstrate that the multimodal causal reasoning capabilities of current multimodal large language models in real-world scenarios still require substantial improvement.

Zilin Xiao, Ming Gong, Jie Wu et al.

Generative approaches powered by large language models (LLMs) have demonstrated emergent abilities in tasks that require complex reasoning abilities. Yet the generative nature still makes the generated content suffer from hallucinations, thus unsuitable for entity-centric tasks like entity linking (EL) requiring precise entity predictions over a large knowledge base. We present Instructed Generative Entity Linker (INSGENEL), the first approach that enables casual language models to perform entity linking over knowledge bases. Several methods to equip language models with EL capability were proposed in this work, including (i) a sequence-to-sequence training EL objective with instruction-tuning, (ii) a novel generative EL framework based on a light-weight potential mention retriever that frees the model from heavy and non-parallelizable decoding, achieving 4$\times$ speedup without compromise on linking metrics. INSGENEL outperforms previous generative alternatives with +6.8 F1 points gain on average, also with a huge advantage in training data efficiency and training compute consumption. In addition, our skillfully engineered in-context learning (ICL) framework for EL still lags behind INSGENEL significantly, reaffirming that the EL task remains a persistent hurdle for general LLMs.

Zilin Xiao, Linjun Shou, Xingyao Zhang et al.

Previous entity disambiguation (ED) methods adopt a discriminative paradigm, where prediction is made based on matching scores between mention context and candidate entities using length-limited encoders. However, these methods often struggle to capture explicit discourse-level dependencies, resulting in incoherent predictions at the abstract level (e.g. topic or category). We propose CoherentED, an ED system equipped with novel designs aimed at enhancing the coherence of entity predictions. Our method first introduces an unsupervised variational autoencoder (VAE) to extract latent topic vectors of context sentences. This approach not only allows the encoder to handle longer documents more effectively, conserves valuable input space, but also keeps a topic-level coherence. Additionally, we incorporate an external category memory, enabling the system to retrieve relevant categories for undecided mentions. By employing step-by-step entity decisions, this design facilitates the modeling of entity-entity interactions, thereby maintaining maximum coherence at the category level. We achieve new state-of-the-art results on popular ED benchmarks, with an average improvement of 1.3 F1 points. Our model demonstrates particularly outstanding performance on challenging long-text scenarios.

Rujiao Long, Yang Li, Xingyao Zhang et al.

Exploration capacity shapes both inference-time performance and reinforcement learning (RL) training for large (vision-) language models, as stochastic sampling often yields redundant reasoning paths with little high-level diversity. This paper proposes Reasoning Palette, a novel latent-modulation framework that endows the model with a stochastic latent variable for strategic contextualization, guiding its internal planning prior to token generation. This latent context is inferred from the mean-pooled embedding of a question-answer pair via a variational autoencoder (VAE), where each sampled latent potentially encodes a distinct reasoning context. During inference, a sampled latent is decoded into learnable token prefixes and prepended to the input prompt, modulating the model's internal reasoning trajectory. In this way, the model performs internal sampling over reasoning strategies prior to output generation, which shapes the style and structure of the entire response sequence. A brief supervised fine-tuning (SFT) warm-up phase allows the model to adapt to this latent conditioning. Within RL optimization, Reasoning Palette facilitates structured exploration by enabling on-demand injection for diverse reasoning modes, significantly enhancing exploration efficiency and sustained learning capability. Experiments across multiple reasoning benchmarks demonstrate that our method enables interpretable and controllable control over the (vision-) language model's strategic behavior, thereby achieving consistent performance gains over standard RL methods.

Xiangru Tang, Xingyao Zhang, Yanjun Shao et al.

Large language models (LLM) excel at a variety of natural language processing tasks, yet they struggle to generate personalized content for individuals, particularly in real-world scenarios like scientific writing. Addressing this challenge, we introduce STEP-BACK PROFILING to personalize LLMs by distilling user history into concise profiles, including essential traits and preferences of users. To conduct the experiments, we construct a Personalized Scientific Writing (PSW) dataset to study multi-user personalization. PSW requires the models to write scientific papers given specialized author groups with diverse academic backgrounds. As for the results, we demonstrate the effectiveness of capturing user characteristics via STEP-BACK PROFILING for collaborative writing. Moreover, our approach outperforms the baselines by up to 3.6 points on the general personalization benchmark (LaMP), including 7 personalization LLM tasks. Our ablation studies validate the contributions of different components in our method and provide insights into our task definition. Our dataset and code are available at \url{https://github.com/gersteinlab/step-back-profiling}.

Donglin Zhuang, Xingyao Zhang, Shuaiwen Leon Song et al.

The quest for determinism in machine learning has disproportionately focused on characterizing the impact of noise introduced by algorithmic design choices. In this work, we address a less well understood and studied question: how does our choice of tooling introduce randomness to deep neural network training. We conduct large scale experiments across different types of hardware, accelerators, state of art networks, and open-source datasets, to characterize how tooling choices contribute to the level of non-determinism in a system, the impact of said non-determinism, and the cost of eliminating different sources of noise. Our findings are surprising, and suggest that the impact of non-determinism in nuanced. While top-line metrics such as top-1 accuracy are not noticeably impacted, model performance on certain parts of the data distribution is far more sensitive to the introduction of randomness. Our results suggest that deterministic tooling is critical for AI safety. However, we also find that the cost of ensuring determinism varies dramatically between neural network architectures and hardware types, e.g., with overhead up to $746\%$, $241\%$, and $196\%$ on a spectrum of widely used GPU accelerator architectures, relative to non-deterministic training. The source code used in this paper is available at https://github.com/usyd-fsalab/NeuralNetworkRandomness.

Yijia Luo, Yulin Song, Xingyao Zhang et al.

Recent advancements in large language models (LLMs) have demonstrated remarkable reasoning capabilities through long chain-of-thought (CoT) reasoning. The R1 distillation scheme has emerged as a promising approach for training cost-effective models with enhanced reasoning abilities. However, the underlying mechanisms driving its effectiveness remain unclear. This study examines the universality of distillation data and identifies key components that enable the efficient transfer of long-chain reasoning capabilities in LLM distillation. Our findings reveal that the effectiveness of long CoT reasoning distillation from teacher models like Qwen-QwQ degrades significantly on nonhomologous models, challenging the assumed universality of current distillation methods. To gain deeper insights into the structure and patterns of long CoT reasoning, we propose DLCoT (Deconstructing Long Chain-of-Thought), a distillation data enhancement framework. DLCoT consists of three key steps: (1) data segmentation to decompose complex long CoT structures, (2) simplification by eliminating unsolvable and redundant solutions, and (3) optimization of intermediate error states. Our approach significantly improves model performance and token efficiency, facilitating the development of high-performance LLMs.

Zilin Xiao, Ming Gong, Paola Cascante-Bonilla et al.

We introduce AutoVER, an Autoregressive model for Visual Entity Recognition. Our model extends an autoregressive Multi-modal Large Language Model by employing retrieval augmented constrained generation. It mitigates low performance on out-of-domain entities while excelling in queries that require visually-situated reasoning. Our method learns to distinguish similar entities within a vast label space by contrastively training on hard negative pairs in parallel with a sequence-to-sequence objective without an external retriever. During inference, a list of retrieved candidate answers explicitly guides language generation by removing invalid decoding paths. The proposed method achieves significant improvements across different dataset splits in the recently proposed Oven-Wiki benchmark. Accuracy on the Entity seen split rises from 32.7% to 61.5%. It also demonstrates superior performance on the unseen and query splits by a substantial double-digit margin.

Ranjie Duan, Jiexi Liu, Xiaojun Jia et al.

Large language models (LLMs) typically deploy safety mechanisms to prevent harmful content generation. Most current approaches focus narrowly on risks posed by malicious actors, often framing risks as adversarial events and relying on defensive refusals. However, in real-world settings, risks also come from non-malicious users seeking help while under psychological distress (e.g., self-harm intentions). In such cases, the model's response can strongly influence the user's next actions. Simple refusals may lead them to repeat, escalate, or move to unsafe platforms, creating worse outcomes. We introduce Constructive Safety Alignment (CSA), a human-centric paradigm that protects against malicious misuse while actively guiding vulnerable users toward safe and helpful results. Implemented in Oyster-I (Oy1), CSA combines game-theoretic anticipation of user reactions, fine-grained risk boundary discovery, and interpretable reasoning control, turning safety into a trust-building process. Oy1 achieves state-of-the-art safety among open models while retaining high general capabilities. On our Constructive Benchmark, it shows strong constructive engagement, close to GPT-5, and unmatched robustness on the Strata-Sword jailbreak dataset, nearing GPT-o1 levels. By shifting from refusal-first to guidance-first safety, CSA redefines the model-user relationship, aiming for systems that are not just safe, but meaningfully helpful. We release Oy1, code, and the benchmark to support responsible, user-centered AI.

Haibin Chen, Kangtao Lv, Chengwei Hu et al.

With the increasing use of Large Language Models (LLMs) in fields such as e-commerce, domain-specific concept evaluation benchmarks are crucial for assessing their domain capabilities. Existing LLMs may generate factually incorrect information within the complex e-commerce applications. Therefore, it is necessary to build an e-commerce concept benchmark. Existing benchmarks encounter two primary challenges: (1) handle the heterogeneous and diverse nature of tasks, (2) distinguish between generality and specificity within the e-commerce field. To address these problems, we propose \textbf{ChineseEcomQA}, a scalable question-answering benchmark focused on fundamental e-commerce concepts. ChineseEcomQA is built on three core characteristics: \textbf{Focus on Fundamental Concept}, \textbf{E-commerce Generality} and \textbf{E-commerce Expertise}. Fundamental concepts are designed to be applicable across a diverse array of e-commerce tasks, thus addressing the challenge of heterogeneity and diversity. Additionally, by carefully balancing generality and specificity, ChineseEcomQA effectively differentiates between broad e-commerce concepts, allowing for precise validation of domain capabilities. We achieve this through a scalable benchmark construction process that combines LLM validation, Retrieval-Augmented Generation (RAG) validation, and rigorous manual annotation. Based on ChineseEcomQA, we conduct extensive evaluations on mainstream LLMs and provide some valuable insights. We hope that ChineseEcomQA could guide future domain-specific evaluations, and facilitate broader LLM adoption in e-commerce applications.

Tianqianjin Lin, Xi Zhao, Xingyao Zhang et al.

Reinforcement learning (RL) can refine the reasoning abilities of large language models (LLMs), but critically depends on a key prerequisite: the LLM can already generate high-utility reasoning paths with non-negligible probability. For tasks beyond the LLM's current competence, such reasoning path can be hard to sample, and learning risks reinforcing familiar but suboptimal reasoning. We are motivated by the insight from cognitive science that Why is this the answer is often an easier question than What is the answer, as it avoids the heavy cognitive load of open-ended exploration, opting instead for explanatory reconstruction-systematically retracing the reasoning that links a question to its answer. We show that LLMs can similarly leverage answers to derive high-quality reasoning paths. We formalize this phenomenon and prove that conditioning on answer provably increases the expected utility of sampled reasoning paths, thereby transforming intractable problems into learnable ones. Building on this insight, we introduce RAVR (Reference-Answer-guided Variational Reasoning), an end-to-end framework that uses answer-conditioned reasoning as a variational surrogate for question-only reasoning. Experiments in both general and math domains demonstrate consistent improvements over strong baselines. We further analyze the reasoning behavior and find that RAVR reduces hesitation, strengthens conclusion consolidation, and promotes problem-specific strategies in reasoning.

Qiyu Wan, Haojun Xia, Xingyao Zhang et al.

Bayesian Neural Networks (BNNs) that possess a property of uncertainty estimation have been increasingly adopted in a wide range of safety-critical AI applications which demand reliable and robust decision making, e.g., self-driving, rescue robots, medical image diagnosis. The training procedure of a probabilistic BNN model involves training an ensemble of sampled DNN models, which induces orders of magnitude larger volume of data movement than training a single DNN model. In this paper, we reveal that the root cause for BNN training inefficiency originates from the massive off-chip data transfer by Gaussian Random Variables (GRVs). To tackle this challenge, we propose a novel design that eliminates all the off-chip data transfer by GRVs through the reversed shifting of Linear Feedback Shift Registers (LFSRs) without incurring any training accuracy loss. To efficiently support our LFSR reversion strategy at the hardware level, we explore the design space of the current DNN accelerators and identify the optimal computation mapping scheme to best accommodate our strategy. By leveraging this finding, we design and prototype the first highly efficient BNN training accelerator, named Shift-BNN, that is low-cost and scalable. Extensive evaluation on five representative BNN models demonstrates that Shift-BNN achieves an average of 4.9x (up to 10.8x) boost in energy efficiency and 1.6x (up to 2.8x) speedup over the baseline DNN training accelerator.

Xingyao Zhang, Linjun Shou, Jian Pei et al.

The abundant semi-structured data on the Web, such as HTML-based tables and lists, provide commercial search engines a rich information source for question answering (QA). Different from plain text passages in Web documents, Web tables and lists have inherent structures, which carry semantic correlations among various elements in tables and lists. Many existing studies treat tables and lists as flat documents with pieces of text and do not make good use of semantic information hidden in structures. In this paper, we propose a novel graph representation of Web tables and lists based on a systematic categorization of the components in semi-structured data as well as their relations. We also develop pre-training and reasoning techniques on the graph model for the QA task. Extensive experiments on several real datasets collected from a commercial engine verify the effectiveness of our approach. Our method improves F1 score by 3.90 points over the state-of-the-art baselines.

Xingyao Zhang, Cao Xiao, Lucas M. Glass et al.

Clinical trials are essential for drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The core problem of patient-trial matching is to find qualified patients for a trial, where patient information is stored in electronic health records (EHR) while trial eligibility criteria (EC) are described in text documents available on the web. How to represent longitudinal patient EHR? How to extract complex logical rules from EC? Most existing works rely on manual rule-based extraction, which is time consuming and inflexible for complex inference. To address these challenges, we proposed DeepEnroll, a cross-modal inference learning model to jointly encode enrollment criteria (text) and patients records (tabular data) into a shared latent space for matching inference. DeepEnroll applies a pre-trained Bidirectional Encoder Representations from Transformers(BERT) model to encode clinical trial information into sentence embedding. And uses a hierarchical embedding model to represent patient longitudinal EHR. In addition, DeepEnroll is augmented by a numerical information embedding and entailment module to reason over numerical information in both EC and EHR. These encoders are trained jointly to optimize patient-trial matching score. We evaluated DeepEnroll on the trial-patient matching task with demonstrated on real world datasets. DeepEnroll outperformed the best baseline by up to 12.4% in average F1.

Xingyao Zhang, Shuaiwen Leon Song, Chenhao Xie et al.

In recent years, the CNNs have achieved great successes in the image processing tasks, e.g., image recognition and object detection. Unfortunately, traditional CNN's classification is found to be easily misled by increasingly complex image features due to the usage of pooling operations, hence unable to preserve accurate position and pose information of the objects. To address this challenge, a novel neural network structure called Capsule Network has been proposed, which introduces equivariance through capsules to significantly enhance the learning ability for image segmentation and object detection. Due to its requirement of performing a high volume of matrix operations, CapsNets have been generally accelerated on modern GPU platforms that provide highly optimized software library for common deep learning tasks. However, based on our performance characterization on modern GPUs, CapsNets exhibit low efficiency due to the special program and execution features of their routing procedure, including massive unshareable intermediate variables and intensive synchronizations, which are very difficult to optimize at software level. To address these challenges, we propose a hybrid computing architecture design named \textit{PIM-CapsNet}. It preserves GPU's on-chip computing capability for accelerating CNN types of layers in CapsNet, while pipelining with an off-chip in-memory acceleration solution that effectively tackles routing procedure's inefficiency by leveraging the processing-in-memory capability of today's 3D stacked memory. Using routing procedure's inherent parallellization feature, our design enables hierarchical improvements on CapsNet inference efficiency through minimizing data movement and maximizing parallel processing in memory.