Ping Chen

Feng Yang, Jie Liu, Yubo Pang et al.

Automated pathology report generation from Whole Slide Images (WSIs) has attracted increasing attention in digital pathology. However, existing methods are predominantly developed under single-organ settings, overlooking the multi-organ scenarios encountered in clinical practice, where organ types typically follow a long-tailed distribution. To address this gap, we identify two critical biases: (1) visual representation bias, where the encoder favors head-class patterns over tail-class discriminative features, and (2) textual decoding bias, where the decoder overfits to head-class narrative patterns, yielding diagnostically unreliable outputs for tail-class organs. To mitigate these two biases, we propose a novel Prior-anchored multi-Organ pathology report Generation framework (PriOrGen). Specifically, a Visual-Prototype Anchored Bottleneck module leverages the information bottleneck principle with learnable anchor representations to selectively retain diagnostically relevant visual information while filtering out head-biased redundancy. Secondly, a Meta-Report Anchored Bank module constructs an organ-specific meta-report anchored bank and retrieves organ-faithful textual priors to steer the decoder away from head-class narrative patterns. Extensive experiments on a multi- organ pathology dataset demonstrate that our method effectively mitigates long-tail biases and achieves superior report generation performance across both head and tail organ categories compared to state-of-the-art methods.

Xue Tan, Yi Zheng, Chang Huo et al.

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by incorporating external knowledge, effectively mitigating their inherent knowledge limitations. However, RAG remains vulnerable to poisoning attacks that manipulate retrieved texts to mislead model outputs. Existing defense mechanisms often lack theoretical robustness guarantees and perform unreliably when the LLM has limited knowledge of the retrieved content. In this work, we propose PRA-RAG, a provably robust retrieval aggregation algorithm designed to defend against poisoning attacks on retrieved texts. PRA-RAG samples multiple combinations of retrieved texts and utilizes geometric structures in the embedding space to identify a robust subset, from which a stable aggregated representation is derived. We provide theoretical bounds on the maximum impact of poisoned retrieved content and establish a quantitative measure of RAG's robustness. Experiments across multiple benchmarks and RAG architectures demonstrate that PRA-RAG reduces the attack success rate to as low as 1% while maintaining an accuracy of 71%, significantly outperforming representative state-of-the-art methods.