Yang Zhang

Huazhong Zhang, Xiaowen Fu, Yang Zhang et al.

Open-World Object Detection (OWOD) requires detectors to identify previously unseen objects as unknown and incrementally incorporate them into the set of known categories, while preserving previously acquired knowledge. Existing frameworks rely heavily on exemplar replay to mitigate catastrophic forgetting, but in some real applications, storing raw data conflicts with data access restrictions and leads to data exposure risks, while incurring significant memory overhead. In this paper, we propose REAL-OW, a novel rehearsal-free framework that decouples incremental knowledge through a collaborative adapter architecture based on Low-Rank Adaptation (LoRA). Specifically, we deploy General Adapters (GAs) in the backbone to enable the significance-aware refinement of cross-task universal representations, while Specific Adapters (SAs) in the decoder provide orthogonal storage for task-specific expertise. To resolve representation drift in objectness modeling under rehearsal-free constraints, we introduce Dual-Stage Objectness Modeling (DSOM), which alternates between feature aggregation and boundary consolidation to stabilize objectness distributions while maintaining the separation between known and unknown categories. Furthermore, DSOM is supported by a Calibrated Gaussian Negative Log-Likelihood (CG-NLL) distance tailored for the dispersed feature distributions inherent in rehearsal-free settings. Extensive evaluations demonstrate that REAL-OW achieves state-of-the-art performance, surpassing existing exemplar replay methods in both detection precision and unknown discovery. Our approach establishes a new baseline for rehearsal-free OWOD.

Yujun Feng, Yuqi Zhang, Jingyi Huang et al.

The Variational Quantum Eigensolver (VQE) is essential for molecular simulation in drug discovery, but hardware noise and algorithmic limits restrict its precision. While the NVIDIA CUDA-Q platform mitigates some hardware issues via exact simulation, it lacks Qiskit support and restricts parallelization. To solve this, we introduce Graph-VQE, a novel framework that extends CUDA-Q with optimization-level parallelism. Graph-VQE leverages amino acid sequence structures by partitioning Hamiltonian interaction graphs into weakly coupled clusters using Louvain community detection. These clusters undergo restricted updates on the full-Hamiltonian objective, followed by a global refinement stage utilizing Hamiltonian batching. Furthermore, a custom Qiskit-CUDA-Q integration layer enables standard workflows with GPU acceleration. Evaluations on protein folding tasks prove that Graph-VQE outperforms baselines, achieving lower final energies. It delivers competitive RMSD and binding affinity compared to AlphaFold3 and IBM quantum processors while maintaining stable quality across multi-GPU environments, thereby providing a highly practical path toward high-fidelity biomolecular simulations.