Xiaobo Xia

Jianing Qiu, Jian Wu, Hao Wei et al.

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM provides a foundation to foster multiple ophthalmic artificial intelligence (AI) applications, such as disease screening and diagnosis, disease prognosis, subclassification of disease phenotype, and systemic biomarker and disease prediction, with each application enhanced with expert-level intelligence and accuracy. The generalist intelligence of VisionFM outperformed ophthalmologists with basic and intermediate levels in jointly diagnosing 12 common ophthalmic diseases. Evaluated on a new large-scale ophthalmic disease diagnosis benchmark database, as well as a new large-scale segmentation and detection benchmark database, VisionFM outperformed strong baseline deep neural networks. The ophthalmic image representations learned by VisionFM exhibited noteworthy explainability, and demonstrated strong generalizability to new ophthalmic modalities, disease spectrum, and imaging devices. As a foundation model, VisionFM has a large capacity to learn from diverse ophthalmic imaging data and disparate datasets. To be commensurate with this capacity, in addition to the real data used for pre-training, we also generated and leveraged synthetic ophthalmic imaging data. Experimental results revealed that synthetic data that passed visual Turing tests, can also enhance the representation learning capability of VisionFM, leading to substantial performance gains on downstream ophthalmic AI tasks. Beyond the ophthalmic AI applications developed, validated, and demonstrated in this work, substantial further applications can be achieved in an efficient and cost-effective manner using VisionFM as the foundation.

Xiaobo Xia, Jiale Liu, Shaokun Zhang et al.

Coreset selection is powerful in reducing computational costs and accelerating data processing for deep learning algorithms. It strives to identify a small subset from large-scale data, so that training only on the subset practically performs on par with full data. Practitioners regularly desire to identify the smallest possible coreset in realistic scenes while maintaining comparable model performance, to minimize costs and maximize acceleration. Motivated by this desideratum, for the first time, we pose the problem of refined coreset selection, in which the minimal coreset size under model performance constraints is explored. Moreover, to address this problem, we propose an innovative method, which maintains optimization priority order over the model performance and coreset size, and efficiently optimizes them in the coreset selection procedure. Theoretically, we provide the convergence guarantee of the proposed method. Empirically, extensive experiments confirm its superiority compared with previous strategies, often yielding better model performance with smaller coreset sizes.

Lei Zhang, Yunshui Li, Jiaming Li et al.

Some recently developed code large language models (Code LLMs) have been pre-trained on repository-level code data (Repo-Code LLMs), enabling these models to recognize repository structures and utilize cross-file information for code completion. However, in real-world development scenarios, simply concatenating the entire code repository often exceeds the context window limits of these Repo-Code LLMs, leading to significant performance degradation. In this study, we conducted extensive preliminary experiments and analyses on six Repo-Code LLMs. The results indicate that maintaining the topological dependencies of files and increasing the code file content in the completion prompts can improve completion accuracy; pruning the specific implementations of functions in all dependent files does not significantly reduce the accuracy of completions. Based on these findings, we proposed a strategy named Hierarchical Context Pruning (HCP) to construct completion prompts with high informational code content. The HCP models the code repository at the function level, maintaining the topological dependencies between code files while removing a large amount of irrelevant code content, significantly reduces the input length for repository-level code completion. We applied the HCP strategy in experiments with six Repo-Code LLMs, and the results demonstrate that our proposed method can significantly enhance completion accuracy while substantially reducing the length of input. Our code and data are available at https://github.com/Hambaobao/HCP-Coder.