Eduardo Pooch

Alessia Hu, Regina Beets-Tan, Lishan Cai et al.

Magnetic Resonance Imaging (MRI) plays an important role in identifying clinically significant prostate cancer (csPCa), yet automated methods face challenges such as data imbalance, variable tumor sizes, and a lack of annotated data. This study introduces Anomaly-Driven U-Net (adU-Net), which incorporates anomaly maps derived from biparametric MRI sequences into a deep learning-based segmentation framework to improve csPCa identification. We conduct a comparative analysis of anomaly detection methods and evaluate the integration of anomaly maps into the segmentation pipeline. Anomaly maps, generated using Fixed-Point GAN reconstruction, highlight deviations from normal prostate tissue, guiding the segmentation model to potential cancerous regions. We compare the performance by using the average score, computed as the mean of the AUROC and Average Precision (AP). On the external test set, adU-Net achieves the best average score of 0.618, outperforming the baseline nnU-Net model (0.605). The results demonstrate that incorporating anomaly detection into segmentation improves generalization and performance, particularly with ADC-based anomaly maps, offering a promising direction for automated csPCa identification.

Andrey Salvi, Nathan Gavenski, Eduardo Pooch et al.

Recently, learning-based approaches for 3D reconstruction from 2D images have gained popularity due to its modern applications, e.g., 3D printers, autonomous robots, self-driving cars, virtual reality, and augmented reality. The computer vision community has applied a great effort in developing functions to reconstruct the full 3D geometry of objects and scenes. However, to extract image features, they rely on convolutional neural networks, which are ineffective in capturing long-range dependencies. In this paper, we propose to substantially improve Occupancy Networks, a state-of-the-art method for 3D object reconstruction. For such we apply the concept of self-attention within the network's encoder in order to leverage complementary input features rather than those based on local regions, helping the encoder to extract global information. With our approach, we were capable of improving the original work in 5.05% of mesh IoU, 0.83% of Normal Consistency, and more than 10X the Chamfer-L1 distance. We also perform a qualitative study that shows that our approach was able to generate much more consistent meshes, confirming its increased generalization power over the current state-of-the-art.

Eduardo H. P. Pooch, Pedro L. Ballester, Rodrigo C. Barros

While deep learning models become more widespread, their ability to handle unseen data and generalize for any scenario is yet to be challenged. In medical imaging, there is a high heterogeneity of distributions among images based on the equipment that generates them and their parametrization. This heterogeneity triggers a common issue in machine learning called domain shift, which represents the difference between the training data distribution and the distribution of where a model is employed. A high domain shift tends to implicate in a poor generalization performance from the models. In this work, we evaluate the extent of domain shift on four of the largest datasets of chest radiographs. We show how training and testing with different datasets (e.g., training in ChestX-ray14 and testing in CheXpert) drastically affects model performance, posing a big question over the reliability of deep learning models trained on public datasets. We also show that models trained on CheXpert and MIMIC-CXR generalize better to other datasets.