Fengwei An

Peng Xu, Wenqi Shao, Mengzhao Chen et al.

Large language models (LLMs) have demonstrated outstanding performance in various tasks, such as text summarization, text question-answering, and etc. While their performance is impressive, the computational footprint due to their vast number of parameters can be prohibitive. Existing solutions such as SparseGPT and Wanda attempt to alleviate this issue through weight pruning. However, their layer-wise approach results in significant perturbation to the model's output and requires meticulous hyperparameter tuning, such as the pruning rate, which can adversely affect overall model performance. To address this, this paper introduces a novel LLM pruning technique dubbed blockwise parameter-efficient sparsity allocation (BESA) by applying a blockwise reconstruction loss. In contrast to the typical layer-wise pruning techniques, BESA is characterized by two distinctive attributes: i) it targets the overall pruning error with respect to individual transformer blocks, and ii) it allocates layer-specific sparsity in a differentiable manner, both of which ensure reduced performance degradation after pruning. Our experiments show that BESA achieves state-of-the-art performance, efficiently pruning LLMs like LLaMA1, and LLaMA2 with 7B to 70B parameters on a single A100 GPU in just five hours. Code is available at https://github.com/OpenGVLab/LLMPrune-BESA.

Yaxin Xu, Yue Zhou, Tianyu Zhao et al.

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale biological problems and rigorous assessment of their tool-augmented capabilities remain limited. We reveal a systematic gap between LLM performance and mechanistic understanding through the proposed cross-scale bio-molecular benchmark: BioMol-LLM-Bench, a unified framework comprising 26 downstream tasks that covers 4 distinct difficulty levels, and computational tools are integrated for a more comprehensive evaluation. Evaluation on 13 representative models reveals 4 main findings: chain-of-thought data provides limited benefit and may even reduce performance on biological tasks; hybrid mamba-attention architectures are more effective for long bio-molecular sequences; supervised fine-tuning improves specialization at the cost of generalization; and current LLMs perform well on classification tasks but remain weak on challenging regression tasks. Together, these findings provide practical guidance for future LLM-based modeling of molecular systems.

Pingcheng Dong, Yonghao Tan, Dong Zhang et al.

Non-linear functions are prevalent in Transformers and their lightweight variants, incurring substantial and frequently underestimated hardware costs. Previous state-of-the-art works optimize these operations by piece-wise linear approximation and store the parameters in look-up tables (LUT), but most of them require unfriendly high-precision arithmetics such as FP/INT 32 and lack consideration of integer-only INT quantization. This paper proposed a genetic LUT-Approximation algorithm namely GQA-LUT that can automatically determine the parameters with quantization awareness. The results demonstrate that GQA-LUT achieves negligible degradation on the challenging semantic segmentation task for both vanilla and linear Transformer models. Besides, proposed GQA-LUT enables the employment of INT8-based LUT-Approximation that achieves an area savings of 81.3~81.7% and a power reduction of 79.3~80.2% compared to the high-precision FP/INT 32 alternatives. Code is available at https:// github.com/PingchengDong/GQA-LUT.