Histopathology Whole Slide Image Analysis with Heterogeneous Graph Representation LearningTsai Hor Chan, Fernando Julio Cendra, Lan Ma et al.
Graph-based methods have been extensively applied to whole-slide histopathology image (WSI) analysis due to the advantage of modeling the spatial relationships among different entities. However, most of the existing methods focus on modeling WSIs with homogeneous graphs (e.g., with homogeneous node type). Despite their successes, these works are incapable of mining the complex structural relations between biological entities (e.g., the diverse interaction among different cell types) in the WSI. We propose a novel heterogeneous graph-based framework to leverage the inter-relationships among different types of nuclei for WSI analysis. Specifically, we formulate the WSI as a heterogeneous graph with "nucleus-type" attribute to each node and a semantic similarity attribute to each edge. We then present a new heterogeneous-graph edge attribute transformer (HEAT) to take advantage of the edge and node heterogeneity during massage aggregating. Further, we design a new pseudo-label-based semantic-consistent pooling mechanism to obtain graph-level features, which can mitigate the over-parameterization issue of conventional cluster-based pooling. Additionally, observing the limitations of existing association-based localization methods, we propose a causal-driven approach attributing the contribution of each node to improve the interpretability of our framework. Extensive experiments on three public TCGA benchmark datasets demonstrate that our framework outperforms the state-of-the-art methods with considerable margins on various tasks. Our codes are available at https://github.com/HKU-MedAI/WSI-HGNN.
SL3D: Self-supervised-Self-labeled 3D RecognitionFernando Julio Cendra, Lan Ma, Jiajun Shen et al.
Deep learning has attained remarkable success in many 3D visual recognition tasks, including shape classification, object detection, and semantic segmentation. However, many of these results rely on manually collecting densely annotated real-world 3D data, which is highly time-consuming and expensive to obtain, limiting the scalability of 3D recognition tasks. Thus, we study unsupervised 3D recognition and propose a Self-supervised-Self-Labeled 3D Recognition (SL3D) framework. SL3D simultaneously solves two coupled objectives, i.e., clustering and learning feature representation to generate pseudo-labeled data for unsupervised 3D recognition. SL3D is a generic framework and can be applied to solve different 3D recognition tasks, including classification, object detection, and semantic segmentation. Extensive experiments demonstrate its effectiveness. Code is available at https://github.com/fcendra/sl3d.
16.4CVJul 26, 2024
PromptCCD: Learning Gaussian Mixture Prompt Pool for Continual Category DiscoveryFernando Julio Cendra, Bingchen Zhao, Kai Han
We tackle the problem of Continual Category Discovery (CCD), which aims to automatically discover novel categories in a continuous stream of unlabeled data while mitigating the challenge of catastrophic forgetting -- an open problem that persists even in conventional, fully supervised continual learning. To address this challenge, we propose PromptCCD, a simple yet effective framework that utilizes a Gaussian Mixture Model (GMM) as a prompting method for CCD. At the core of PromptCCD lies the Gaussian Mixture Prompting (GMP) module, which acts as a dynamic pool that updates over time to facilitate representation learning and prevent forgetting during category discovery. Moreover, GMP enables on-the-fly estimation of category numbers, allowing PromptCCD to discover categories in unlabeled data without prior knowledge of the category numbers. We extend the standard evaluation metric for Generalized Category Discovery (GCD) to CCD and benchmark state-of-the-art methods on diverse public datasets. PromptCCD significantly outperforms existing methods, demonstrating its effectiveness. Project page: https://visual-ai.github.io/promptccd .
8.4CVSep 26, 2025
PartCo: Part-Level Correspondence Priors Enhance Category DiscoveryFernando Julio Cendra, Kai Han
Generalized Category Discovery (GCD) aims to identify both known and novel categories within unlabeled data by leveraging a set of labeled examples from known categories. Existing GCD methods primarily depend on semantic labels and global image representations, often overlooking the detailed part-level cues that are crucial for distinguishing closely related categories. In this paper, we introduce PartCo, short for Part-Level Correspondence Prior, a novel framework that enhances category discovery by incorporating part-level visual feature correspondences. By leveraging part-level relationships, PartCo captures finer-grained semantic structures, enabling a more nuanced understanding of category relationships. Importantly, PartCo seamlessly integrates with existing GCD methods without requiring significant modifications. Our extensive experiments on multiple benchmark datasets demonstrate that PartCo significantly improves the performance of current GCD approaches, achieving state-of-the-art results by bridging the gap between semantic labels and part-level visual compositions, thereby setting new benchmarks for GCD. Project page: https://visual-ai.github.io/partco