Shaoshuai Yang

Yiming Shi, Shaoshuai Yang, Xun Zhu et al.

Medical image analysis is essential in modern healthcare. Deep learning has redirected research focus toward complex medical multimodal tasks, including report generation and visual question answering. Traditional task-specific models often fall short in handling these challenges. Large vision-language models (LVLMs) offer new solutions for solving such tasks. In this study, we build on the popular LLaVA framework to systematically explore model architectures and training strategies for both 2D and 3D medical LVLMs. We present extensive empirical findings and practical guidance. To support reproducibility and future research, we release a modular codebase, MedM-VL, and two pre-trained models: MedM-VL-2D for 2D medical image analysis and MedM-VL-CT-Chest for 3D CT-based applications. The code is available at: https://github.com/MSIIP/MedM-VL

Xun Zhu, Fanbin Mo, Xi Chen et al.

The rise of multimodal large language models (MLLMs) has sparked an unprecedented wave of applications in the field of medical imaging analysis. However, as one of the earliest and most fundamental tasks integrated into this paradigm, medical image classification reveals a sobering reality: state-of-the-art medical MLLMs consistently underperform compared to traditional deep learning models, despite their overwhelming advantages in pre-training data and model parameters. This paradox prompts a critical rethinking: where exactly does the performance degradation originate? In this paper, we conduct extensive experiments on 14 open-source medical MLLMs across three representative image classification datasets. Moving beyond superficial performance benchmarking, we employ feature probing to track the information flow of visual features module-by-module and layer-by-layer throughout the entire MLLM pipeline, enabling explicit visualization of where and how classification signals are distorted, diluted, or overridden. As the first attempt to dissect classification performance degradation in medical MLLMs, our findings reveal four failure modes: 1) quality limitation in visual representation, 2) fidelity loss in connector projection, 3) comprehension deficit in LLM reasoning, and 4) misalignment of semantic mapping. Meanwhile, we introduce quantitative scores that characterize the healthiness of feature evolution, enabling principled comparisons across diverse MLLMs and datasets. Furthermore, we provide insightful discussions centered on the critical barriers that prevent current medical MLLMs from fulfilling their promised clinical potential. We hope that our work provokes rethinking within the community-highlighting that the road from high expectations to clinically deployable MLLMs remains long and winding.