Zhaoqian Xue

Zhaoqian Xue, Beichen Wang, Suiyuan Zhu et al.

This study introduces "CosmoAgent," an innovative artificial intelligence system that utilizes Large Language Models (LLMs) to simulate complex interactions between human and extraterrestrial civilizations. This paper introduces a mathematical model for quantifying the levels of civilization development and further employs a state transition matrix approach to evaluate their trajectories. Through this methodology, our study quantitatively analyzes the growth trajectories of civilizations, providing insights into future decision-making at critical points of growth and saturation. Furthermore, this paper acknowledges the vast diversity of potential living conditions across the universe, which could foster unique cosmologies, ethical codes, and worldviews among different civilizations. Recognizing the Earth-centric bias inherent in current LLM designs, we propose the novel concept of using LLM agents with diverse ethical paradigms and simulating interactions between entities with distinct moral principles. This innovative research not only introduces a novel method for comprehending potential inter-civilizational dynamics but also holds practical value in enabling entities with divergent value systems to strategize, prevent conflicts, and engage in games under conditions of asymmetric information. The accompanying code is available at https://github.com/MingyuJ666/Simulating-Alien-Civilizations-with-LLM-based-Agents.

Kai Wei, Raymond Li, Xi Zhu et al.

Retrieval-Augmented Generation (RAG) has emerged as a foundational paradigm for grounding large language models in external knowledge. While adaptive retrieval mechanisms have improved retrieval efficiency, existing approaches treat post-retrieval failure as a signal to retry rather than to diagnose -- leaving the structural causes of query-evidence misalignment unaddressed. We observe that a significant portion of persistent retrieval failures stem not from the absence of relevant evidence but from an alignment gap between the query and the evidence space. We propose Skill-RAG, a failure-aware RAG framework that couples a lightweight hidden-state prober with a prompt-based skill router. The prober gates retrieval at two pipeline stages; upon detecting a failure state, the skill router diagnoses the underlying cause and selects among four retrieval skills -- query rewriting, question decomposition, evidence focusing, and an exit skill for truly irreducible cases -- to correct misalignment before the next generation attempt. Experiments across multiple open-domain QA and complex reasoning benchmarks show that Skill-RAG substantially improves accuracy on hard cases persisting after multi-turn retrieval, with particularly strong gains on out-of-distribution datasets. Representation-space analyses further reveal that the proposed skills occupy structured, separable regions of the failure state space, supporting the view that query-evidence misalignment is a typed rather than monolithic phenomenon.

Xiaoran Xu, Zhaoqian Xue, Chi Zhang et al.

Investigating the public experience of urgent care facilities is essential for promoting community healthcare development. Traditional survey methods often fall short due to limited scope, time, and spatial coverage. Crowdsourcing through online reviews or social media offers a valuable approach to gaining such insights. With recent advancements in large language models (LLMs), extracting nuanced perceptions from reviews has become feasible. This study collects Google Maps reviews across the DMV and Florida areas and conducts prompt engineering with the GPT model to analyze the aspect-based sentiment of urgent care. We first analyze the geospatial patterns of various aspects, including interpersonal factors, operational efficiency, technical quality, finances, and facilities. Next, we determine Census Block Group(CBG)-level characteristics underpinning differences in public perception, including population density, median income, GINI Index, rent-to-income ratio, household below poverty rate, no insurance rate, and unemployment rate. Our results show that interpersonal factors and operational efficiency emerge as the strongest determinants of patient satisfaction in urgent care, while technical quality, finances, and facilities show no significant independent effects when adjusted for in multivariate models. Among socioeconomic and demographic factors, only population density demonstrates a significant but modest association with patient ratings, while the remaining factors exhibit no significant correlations. Overall, this study highlights the potential of crowdsourcing to uncover the key factors that matter to residents and provide valuable insights for stakeholders to improve public satisfaction with urgent care.

Zhaoqian Xue, Guanhong Liu, Kai Wei et al.

Access to health resources is a critical determinant of public well-being and societal resilience, particularly during public health crises when demand for medical services and preventive care surges. However, disparities in accessibility persist across demographic and geographic groups, raising concerns about equity. Traditional survey methods often fall short due to limitations in coverage, cost, and timeliness. This study leverages crowdsourced data from Google Maps reviews, applying advanced natural language processing techniques, specifically ModernBERT, to extract insights on public perceptions of health resource accessibility in the United States during the COVID-19 pandemic. Additionally, we employ Partial Least Squares regression to examine the relationship between accessibility perceptions and key socioeconomic and demographic factors including political affiliation, racial composition, and educational attainment. Our findings reveal that public perceptions of health resource accessibility varied significantly across the U.S., with disparities peaking during the pandemic and slightly easing post-crisis. Political affiliation, racial demographics, and education levels emerged as key factors shaping these perceptions. These findings underscore the need for targeted interventions and policy measures to address inequities, fostering a more inclusive healthcare infrastructure that can better withstand future public health challenges.

Qingcheng Zeng, Guanhong Liu, Zhaoqian Xue et al.

On July 13, 2024, at the Trump rally in Pennsylvania, someone attempted to assassinate Republican Presidential Candidate Donald Trump. This attempt sparked a large-scale discussion on social media. We collected posts from X (formerly known as Twitter) one week before and after the assassination attempt and aimed to model the short-term effects of such a ``shock'' on public opinions and discussion topics. Specifically, our study addresses three key questions: first, we investigate how public sentiment toward Donald Trump shifts over time and across regions (RQ1) and examine whether the assassination attempt itself significantly affects public attitudes, independent of the existing political alignments (RQ2). Finally, we explore the major themes in online conversations before and after the crisis, illustrating how discussion topics evolved in response to this politically charged event (RQ3). By integrating large language model-based sentiment analysis, difference-in-differences modeling, and topic modeling techniques, we find that following the attempt the public response was broadly sympathetic to Trump rather than polarizing, despite baseline ideological and regional disparities.

Zhijie Duan, Kai Wei, Zhaoqian Xue et al.

Social media is a rich source of real-world data that captures valuable patient experience information for pharmacovigilance. However, mining data from unstructured and noisy social media content remains a challenging task. We present a systematic framework that leverages large language models (LLMs) to extract medication side effects from social media and organize them into a knowledge graph (KG). We apply this framework to semaglutide for weight loss using data from Reddit. Using the constructed knowledge graph, we perform comprehensive analyses to investigate reported side effects across different semaglutide brands over time. These findings are further validated through comparison with adverse events reported in the FAERS database, providing important patient-centered insights into semaglutide's side effects that complement its safety profile and current knowledge base of semaglutide for both healthcare professionals and patients. Our work demonstrates the feasibility of using LLMs to transform social media data into structured KGs for pharmacovigilance.