Gabriel García

Julio Silva-Rodríguez, Elena Payá-Bosch, Gabriel García et al.

Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the glandular structural analysis in histology images. Hence, accurate gland detection and segmentation is crucial for a successful prediction. The methodological basis of this work is a prostate gland segmentation based on U-Net convolutional neural network architectures modified with residual and multi-resolution blocks, trained using data augmentation techniques. The residual configuration outperforms in the test subset the previous state-of-the-art approaches in an image-level comparison, reaching an average Dice Index of 0.77.

Gabriel García, Rocío del Amor, Adrián Colomer et al.

Nowadays, glaucoma is the leading cause of blindness worldwide. We propose in this paper two different deep-learning-based approaches to address glaucoma detection just from raw circumpapillary OCT images. The first one is based on the development of convolutional neural networks (CNNs) trained from scratch. The second one lies in fine-tuning some of the most common state-of-the-art CNNs architectures. The experiments were performed on a private database composed of 93 glaucomatous and 156 normal B-scans around the optic nerve head of the retina, which were diagnosed by expert ophthalmologists. The validation results evidence that fine-tuned CNNs outperform the networks trained from scratch when small databases are addressed. Additionally, the VGG family of networks reports the most promising results, with an area under the ROC curve of 0.96 and an accuracy of 0.92, during the prediction of the independent test set.