5.8AINov 6, 2025Code
RxSafeBench: Identifying Medication Safety Issues of Large Language Models in Simulated ConsultationJiahao Zhao, Luxin Xu, Minghuan Tan et al.
Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained by privacy and accessibility issues. Moreover, evaluation of LLMs in realistic clinical consultation settings, particularly regarding medication safety, is still underexplored. To address these gaps, we propose a framework that simulates and evaluates clinical consultations to systematically assess the medication safety capabilities of LLMs. Within this framework, we generate inquiry diagnosis dialogues with embedded medication risks and construct a dedicated medication safety database, RxRisk DB, containing 6,725 contraindications, 28,781 drug interactions, and 14,906 indication-drug pairs. A two-stage filtering strategy ensures clinical realism and professional quality, resulting in the benchmark RxSafeBench with 2,443 high-quality consultation scenarios. We evaluate leading open-source and proprietary LLMs using structured multiple choice questions that test their ability to recommend safe medications under simulated patient contexts. Results show that current LLMs struggle to integrate contraindication and interaction knowledge, especially when risks are implied rather than explicit. Our findings highlight key challenges in ensuring medication safety in LLM-based systems and provide insights into improving reliability through better prompting and task-specific tuning. RxSafeBench offers the first comprehensive benchmark for evaluating medication safety in LLMs, advancing safer and more trustworthy AI-driven clinical decision support.
OpenOmni: Advancing Open-Source Omnimodal Large Language Models with Progressive Multimodal Alignment and Real-Time Self-Aware Emotional Speech SynthesisRun Luo, Ting-En Lin, Haonan Zhang et al.
Recent advancements in omnimodal learning have significantly improved understanding and generation across images, text, and speech, yet these developments remain predominantly confined to proprietary models. The lack of high-quality omnimodal datasets and the challenges of real-time emotional speech synthesis have notably hindered progress in open-source research. To address these limitations, we introduce \name, a two-stage training framework that integrates omnimodal alignment and speech generation to develop a state-of-the-art omnimodal large language model. In the alignment phase, a pre-trained speech model undergoes further training on text-image tasks, enabling (near) zero-shot generalization from vision to speech, outperforming models trained on tri-modal datasets. In the speech generation phase, a lightweight decoder is trained on speech tasks with direct preference optimization, enabling real-time emotional speech synthesis with high fidelity. Experiments show that \name surpasses state-of-the-art models across omnimodal, vision-language, and speech-language benchmarks. It achieves a 4-point absolute improvement on OmniBench over the leading open-source model VITA, despite using 5x fewer training samples and a smaller model size (7B vs. 7x8B). Additionally, \name achieves real-time speech generation with <1s latency at non-autoregressive mode, reducing inference time by 5x compared to autoregressive methods, and improves emotion classification accuracy by 7.7\%
ChARM: Character-based Act-adaptive Reward Modeling for Advanced Role-Playing Language AgentsFeiteng Fang, Ting-En Lin, Yuchuan Wu et al.
Role-Playing Language Agents (RPLAs) aim to simulate characters for realistic and engaging human-computer interactions. However, traditional reward models often struggle with scalability and adapting to subjective conversational preferences. We propose ChARM, a Character-based Act-adaptive Reward Model, addressing these challenges through two innovations: (1) an act-adaptive margin that significantly enhances learning efficiency and generalizability, and (2) a self-evolution mechanism leveraging large-scale unlabeled data to improve training coverage. Additionally, we introduce RoleplayPref, the first large-scale preference dataset specifically for RPLAs, featuring 1,108 characters, 13 subcategories, and 16,888 bilingual dialogues, alongside RoleplayEval, a dedicated evaluation benchmark. Experimental results show a 13% improvement over the conventional Bradley-Terry model in preference rankings. Furthermore, applying ChARM-generated rewards to preference learning techniques (e.g., direct preference optimization) achieves state-of-the-art results on CharacterEval and RoleplayEval. Code and dataset are available at https://github.com/calubkk/ChARM.
Training Superior Sparse Autoencoders for Instruct ModelsJiaming Li, Haoran Ye, Yukun Chen et al.
As large language models (LLMs) grow in scale and capability, understanding their internal mechanisms becomes increasingly critical. Sparse autoencoders (SAEs) have emerged as a key tool in mechanistic interpretability, enabling the extraction of human-interpretable features from LLMs. However, existing SAE training methods are primarily designed for base models, resulting in reduced reconstruction quality and interpretability when applied to instruct models. To bridge this gap, we propose $\underline{\textbf{F}}$inetuning-$\underline{\textbf{a}}$ligned $\underline{\textbf{S}}$equential $\underline{\textbf{T}}$raining ($\textit{FAST}$), a novel training method specifically tailored for instruct models. $\textit{FAST}$ aligns the training process with the data distribution and activation patterns characteristic of instruct models, resulting in substantial improvements in both reconstruction and feature interpretability. On Qwen2.5-7B-Instruct, $\textit{FAST}$ achieves a mean squared error of 0.6468 in token reconstruction, significantly outperforming baseline methods with errors of 5.1985 and 1.5096. In feature interpretability, $\textit{FAST}$ yields a higher proportion of high-quality features, for Llama3.2-3B-Instruct, $21.1\%$ scored in the top range, compared to $7.0\%$ and $10.2\%$ for $\textit{BT(P)}$ and $\textit{BT(F)}$. Surprisingly, we discover that intervening on the activations of special tokens via the SAEs leads to improvements in output quality, suggesting new opportunities for fine-grained control of model behavior. Code, data, and 240 trained SAEs are available at https://github.com/Geaming2002/FAST.
6.7CLApr 22, 2025Code
IPBench: Benchmarking the Knowledge of Large Language Models in Intellectual PropertyQiyao Wang, Guhong Chen, Hongbo Wang et al.
Intellectual Property (IP) is a highly specialized domain that integrates technical and legal knowledge, making it inherently complex and knowledge-intensive. Recent advancements in LLMs have demonstrated their potential to handle IP-related tasks, enabling more efficient analysis, understanding, and generation of IP-related content. However, existing datasets and benchmarks focus narrowly on patents or cover limited aspects of the IP field, lacking alignment with real-world scenarios. To bridge this gap, we introduce IPBench, the first comprehensive IP task taxonomy and a large-scale bilingual benchmark encompassing 8 IP mechanisms and 20 distinct tasks, designed to evaluate LLMs in real-world IP scenarios. We benchmark 17 main LLMs, ranging from general purpose to domain-specific, including chat-oriented and reasoning-focused models, under zero-shot, few-shot, and chain-of-thought settings. Our results show that even the top-performing model, DeepSeek-V3, achieves only 75.8% accuracy, indicating significant room for improvement. Notably, open-source IP and law-oriented models lag behind closed-source general-purpose models. To foster future research, we publicly release IPBench, and will expand it with additional tasks to better reflect real-world complexities and support model advancements in the IP domain. We provide the data and code in the supplementary URLs.
13.9CLJun 3, 2025
STORYTELLER: An Enhanced Plot-Planning Framework for Coherent and Cohesive Story GenerationJiaming Li, Yukun Chen, Ziqiang Liu et al.
Stories are central to human culture, serving to share ideas, preserve traditions, and foster connections. Automatic story generation, a key advancement in artificial intelligence (AI), offers new possibilities for creating personalized content, exploring creative ideas, and enhancing interactive experiences. However, existing methods struggle to maintain narrative coherence and logical consistency. This disconnect compromises the overall storytelling experience, underscoring the need for substantial improvements. Inspired by human cognitive processes, we introduce Storyteller, a novel approach that systemically improves the coherence and consistency of automatically generated stories. Storyteller introduces a plot node structure based on linguistically grounded subject verb object (SVO) triplets, which capture essential story events and ensure a consistent logical flow. Unlike previous methods, Storyteller integrates two dynamic modules, the STORYLINE and narrative entity knowledge graph (NEKG),that continuously interact with the story generation process. This integration produces structurally sound, cohesive and immersive narratives. Extensive experiments demonstrate that Storyteller significantly outperforms existing approaches, achieving an 84.33% average win rate through human preference evaluation. At the same time, it is also far ahead in other aspects including creativity, coherence, engagement, and relevance.