UiHyun Cho

Uihyun Cho, Namhun Kim

Recent advances in deep-learning based denoising methods have improved Low-Dose CT image quality. However, due to distinct HU distributions and diverse anatomical characteristics, a single model often struggles to generalize across multiple anatomies. To address this limitation, we introduce \textbf{Agent-Integrated Denoising Experts (A-IDE)} framework, which integrates three anatomical region-specialized RED-CNN models under the management of decision-making LLM agent. The agent analyzes semantic cues from BiomedCLIP to dynamically route incoming LDCT scans to the most appropriate expert model. We highlight three major advantages of our approach. A-IDE excels in heterogeneous, data-scarce environments. The framework automatically prevents overfitting by distributing tasks among multiple experts. Finally, our LLM-driven agentic pipeline eliminates the need for manual interventions. Experimental evaluations on the Mayo-2016 dataset confirm that A-IDE achieves superior performance in RMSE, PSNR, and SSIM compared to a single unified denoiser.

Namhun Kim, UiHyun Cho

Deep-learning-based denoising methods have significantly improved Low-Dose CT (LDCT) image quality. However, existing models often over-smooth important anatomical details due to their purely data-driven attention mechanisms. To address this challenge, we propose a novel LDCT denoising framework, BioAtt. The key innovation lies in attending anatomical prior distributions extracted from the pretrained vision-language model BiomedCLIP. These priors guide the denoising model to focus on anatomically relevant regions to suppress noise while preserving clinically relevant structures. We highlight three main contributions: BioAtt outperforms baseline and attention-based models in SSIM, PSNR, and RMSE across multiple anatomical regions. The framework introduces a new architectural paradigm by embedding anatomic priors directly into spatial attention. Finally, BioAtt attention maps provide visual confirmation that the improvements stem from anatomical guidance rather than increased model complexity.