Doohyun Park

Jihyeon Baek, Seunghoon Lee, Gitaek Kwon et al.

Out-of-distribution (OOD) detection is essential for building reliable AI systems, as models that produce outputs for invalid inputs cannot be trusted. Although deep learning (DL) is often assumed to outperform traditional machine learning (ML), medical imaging data are typically acquired under standardized protocols, leading to relatively constrained image variability in OOD detection tasks. This motivates a direct comparison between ML and DL approaches in this setting. The two approaches are evaluated on open datasets comprising over 60,000 fundus and non-fundus images across multiple resolutions. Both approaches achieved an AUROC of 1.000 and accuracies between 0.999 and 1.000 on internal and external validation sets, showing comparable detection performance. The ML approach, however, exhibited substantially lower end-to-end latency while maintaining equivalent accuracy, indicating greater computational efficiency. These results suggest that for OOD detection tasks of limited visual complexity, lightweight ML approaches can achieve DL-level performance with significantly reduced computational cost, supporting practical real-world deployment.

Inhyuk Park, Doohyun Park

Noisy labels are common in large-scale medical imaging datasets due to inter-observer variability and ambiguous cases. We propose a statistically grounded and task-agnostic framework, Standardized Loss Aggregation (SLA), for detecting noisy labels at the sample level. SLA quantifies label reliability by aggregating standardized fold-level validation losses across repeated cross-validation runs. This formulation generalizes discrete hard-counting schemes into a continuous estimator that captures both the frequency and magnitude of performance deviations, yielding interpretable and statistically stable noisiness scores. Experiments on a public fundus dataset demonstrate that SLA consistently outperforms the hard-counting baseline across all noise levels and converges substantially faster, especially under low noise ratios where subtle loss variations are informative. Samples with high SLA scores indicate potentially ambiguous or mislabeled cases, guiding efficient re-annotation and improving dataset reliability for any classification task.

Yuan Jin, Antonio Pepe, Gian Marco Melito et al.

The automated analysis of the aortic vessel tree (AVT) from computed tomography angiography (CTA) holds immense clinical potential, but its development has been impeded by a lack of shared, high-quality data. We launched the SEG.A. challenge to catalyze progress in this field by introducing a large, publicly available, multi-institutional dataset for AVT segmentation. The challenge benchmarked automated algorithms on a hidden test set, with subsequent optional tasks in surface meshing for computational simulations. Our findings reveal a clear convergence on deep learning methodologies, with 3D U-Net architectures dominating the top submissions. A key result was that an ensemble of the highest-ranking algorithms significantly outperformed individual models, highlighting the benefits of model fusion. Performance was strongly linked to algorithmic design, particularly the use of customized post-processing steps, and the characteristics of the training data. This initiative not only establishes a new performance benchmark but also provides a lasting resource to drive future innovation toward robust, clinically translatable tools.