Peiqi Wang

Peiqi Wang, William M. Wells, Seth Berkowitz et al.

Image-text multimodal representation learning aligns data across modalities and enables important medical applications, e.g., image classification, visual grounding, and cross-modal retrieval. In this work, we establish a connection between multimodal representation learning and multiple instance learning. Based on this connection, we propose a generic framework for constructing permutation-invariant score functions with many existing multimodal representation learning approaches as special cases. Furthermore, we use the framework to derive a novel contrastive learning approach and demonstrate that our method achieves state-of-the-art results in several downstream tasks.

Peiqi Wang, Yingcheng Liu, Ching-Yun Ko et al.

Self-supervised representation learning on image-text data facilitates crucial medical applications, such as image classification, visual grounding, and cross-modal retrieval. One common approach involves contrasting semantically similar (positive) and dissimilar (negative) pairs of data points. Drawing negative samples uniformly from the training data set introduces false negatives, i.e., samples that are treated as dissimilar but belong to the same class. In healthcare data, the underlying class distribution is nonuniform, implying that false negatives occur at a highly variable rate. To improve the quality of learned representations, we develop a novel approach that corrects for false negatives. Our method can be viewed as a variant of debiased contrastive learning that uses estimated sample-specific class probabilities. We provide theoretical analysis of the objective function and demonstrate the proposed approach on both image and paired image-text data sets. Our experiments illustrate empirical advantages of sample-specific debiasing.

Peiqi Wang, Yikang Shen, Zhen Guo et al.

We aim to select data subsets for the fine-tuning of large language models to more effectively follow instructions. Prior work has emphasized the importance of diversity in dataset curation but relied on heuristics such as the number of tasks. In this paper, we use determinantal point processes to capture the diversity and quality of instruction tuning datasets for subset selection. We propose to measure dataset diversity with log determinant distance that is the distance between the dataset of interest and a maximally diverse reference dataset. Our experiments demonstrate that the proposed diversity measure in the normalized weight gradient space is correlated with downstream instruction-following performance. Consequently, it can be used to inform when data selection is the most helpful and to analyze dataset curation strategies. We demonstrate the utility of our approach on various instruction tuning datasets.

Zhen Guo, Peiqi Wang, Yanwei Wang et al.

Large Language Models (LLMs) have made remarkable advancements in the field of natural language processing. However, their increasing size poses challenges in terms of computational cost. On the other hand, Small Language Models (SLMs) are known for their efficiency, but they often struggle with limited capacity and training data, especially in specific domains. In this paper, we introduce a novel method aimed at improving SLMs in the medical domain using LLM-based generative data augmentation. The objective of our approach is to develop more efficient and capable models that are specifically tailored for specialized applications. Through experiments conducted on the PubMedQA dataset, we demonstrate the effectiveness of LLMs in refining and diversifying existing question-answer pairs. This refinement process leads to improved performance in a significantly smaller model after fine-tuning. Notably, our best SLM, with under 1.6 billion parameters, outperforms the few-shot GPT-4 on the PubMedQA dataset. Our code and generated data are publicly available to facilitate further explorations.

Peiqi Wang, Ruizhi Liao, Daniel Moyer et al.

Adoption of machine learning models in healthcare requires end users' trust in the system. Models that provide additional supportive evidence for their predictions promise to facilitate adoption. We define consistent evidence to be both compatible and sufficient with respect to model predictions. We propose measures of model inconsistency and regularizers that promote more consistent evidence. We demonstrate our ideas in the context of edema severity grading from chest radiographs. We demonstrate empirically that consistent models provide competitive performance while supporting interpretation.

Peiqi Wang, Dongsheng Wang, Yu Ji et al.

The intensive computation and memory requirements of generative adversarial neural networks (GANs) hinder its real-world deployment on edge devices such as smartphones. Despite the success in model reduction of CNNs, neural network quantization methods have not yet been studied on GANs, which are mainly faced with the issues of both the effectiveness of quantization algorithms and the instability of training GAN models. In this paper, we start with an extensive study on applying existing successful methods to quantize GANs. Our observation reveals that none of them generates samples with reasonable quality because of the underrepresentation of quantized values in model weights, and the generator and discriminator networks show different sensitivities upon quantization methods. Motivated by these observations, we develop a novel quantization method for GANs based on EM algorithms, named as QGAN. We also propose a multi-precision algorithm to help find the optimal number of bits of quantized GAN models in conjunction with corresponding result qualities. Experiments on CIFAR-10 and CelebA show that QGAN can quantize GANs to even 1-bit or 2-bit representations with results of quality comparable to original models.

Yu Ji, Zixin Liu, Xing Hu et al.

Neural network (NN) trojaning attack is an emerging and important attack model that can broadly damage the system deployed with NN models. Existing studies have explored the outsourced training attack scenario and transfer learning attack scenario in some small datasets for specific domains, with limited numbers of fixed target classes. In this paper, we propose a more powerful trojaning attack method for both outsourced training attack and transfer learning attack, which outperforms existing studies in the capability, generality, and stealthiness. First, The attack is programmable that the malicious misclassification target is not fixed and can be generated on demand even after the victim's deployment. Second, our trojan attack is not limited in a small domain; one trojaned model on a large-scale dataset can affect applications of different domains that reuse its general features. Thirdly, our trojan design is hard to be detected or eliminated even if the victims fine-tune the whole model.