Xingwei He

Xingwei He, Qianru Zhang, Pengfei Chen et al.

Instruction-following is a critical capability of Large Language Models (LLMs). While existing works primarily focus on assessing how well LLMs adhere to user instructions, they often overlook scenarios where instructions contain conflicting constraints-a common occurrence in complex prompts. The behavior of LLMs under such conditions remains under-explored. To bridge this gap, we introduce ConInstruct, a benchmark specifically designed to assess LLMs' ability to detect and resolve conflicts within user instructions. Using this dataset, we evaluate LLMs' conflict detection performance and analyze their conflict resolution behavior. Our experiments reveal two key findings: (1) Most proprietary LLMs exhibit strong conflict detection capabilities, whereas among open-source models, only DeepSeek-R1 demonstrates similarly strong performance. DeepSeek-R1 and Claude-4.5-Sonnet achieve the highest average F1-scores at 91.5% and 87.3%, respectively, ranking first and second overall. (2) Despite their strong conflict detection abilities, LLMs rarely explicitly notify users about the conflicts or request clarification when faced with conflicting constraints. These results underscore a critical shortcoming in current LLMs and highlight an important area for future improvement when designing instruction-following LLMs.

Xingwei He, Qianru Zhang, A-Long Jin et al.

Factual error correction (FEC) aims to revise factual errors in false claims with minimal editing, making them faithful to the provided evidence. This task is crucial for alleviating the hallucination problem encountered by large language models. Given the lack of paired data (i.e., false claims and their corresponding correct claims), existing methods typically adopt the mask-then-correct paradigm. This paradigm relies solely on unpaired false claims and correct claims, thus being referred to as distantly supervised methods. These methods require a masker to explicitly identify factual errors within false claims before revising with a corrector. However, the absence of paired data to train the masker makes accurately pinpointing factual errors within claims challenging. To mitigate this, we propose to improve FEC by Learning to Inject Factual Errors (LIFE), a three-step distantly supervised method: mask-corrupt-correct. Specifically, we first train a corruptor using the mask-then-corrupt procedure, allowing it to deliberately introduce factual errors into correct text. The corruptor is then applied to correct claims, generating a substantial amount of paired data. After that, we filter out low-quality data, and use the remaining data to train a corrector. Notably, our corrector does not require a masker, thus circumventing the bottleneck associated with explicit factual error identification. Our experiments on a public dataset verify the effectiveness of LIFE in two key aspects: Firstly, it outperforms the previous best-performing distantly supervised method by a notable margin of 10.59 points in SARI Final (19.3% improvement). Secondly, even compared to ChatGPT prompted with in-context examples, LIFE achieves a superiority of 7.16 points in SARI Final.

Xingwei He, Kit Mills Bransby, Ahmet Emir Ulutas et al.

Aims: To develop a deep-learning (DL) framework that will allow fully automated longitudinal and circumferential co-registration of intravascular ultrasound (IVUS) and optical coherence tomography (OCT) images. Methods and results: Data from 230 patients (714 vessels) with acute coronary syndrome that underwent near-infrared spectroscopy (NIRS)-IVUS and OCT imaging in their non-culprit vessels were included in the present analysis. The lumen borders annotated by expert analysts in 61,655 NIRS-IVUS and 62,334 OCT frames, and the side branches and calcific tissue identified in 10,000 NIRS-IVUS frames and 10,000 OCT frames, were used to train DL solutions for the automated extraction of these features. The trained DL solutions were used to process NIRS-IVUS and OCT images and their output was used by a dynamic time warping algorithm to co-register longitudinally the NIRS-IVUS and OCT images, while the circumferential registration of the IVUS and OCT was optimized through dynamic programming. On a test set of 77 vessels from 22 patients, the DL method showed high concordance with the expert analysts for the longitudinal and circumferential co-registration of the two imaging sets (concordance correlation coefficient >0.99 for the longitudinal and >0.90 for the circumferential co-registration). The Williams Index was 0.96 for longitudinal and 0.97 for circumferential co-registration, indicating a comparable performance to the analysts. The time needed for the DL pipeline to process imaging data from a vessel was <90s. Conclusion: The fully automated, DL-based framework introduced in this study for the co-registration of IVUS and OCT is fast and provides estimations that compare favorably to the expert analysts. These features renders it useful in research in the analysis of large-scale data collected in studies that incorporate multimodality imaging to characterize plaque composition.