Tianyang Zhong

Zhengliang Liu, Tianyang Zhong, Yiwei Li et al.

The rise of large language models (LLMs) has marked a pivotal shift in the field of natural language processing (NLP). LLMs have revolutionized a multitude of domains, and they have made a significant impact in the medical field. Large language models are now more abundant than ever, and many of these models exhibit bilingual capabilities, proficient in both English and Chinese. However, a comprehensive evaluation of these models remains to be conducted. This lack of assessment is especially apparent within the context of radiology NLP. This study seeks to bridge this gap by critically evaluating thirty two LLMs in interpreting radiology reports, a crucial component of radiology NLP. Specifically, the ability to derive impressions from radiologic findings is assessed. The outcomes of this evaluation provide key insights into the performance, strengths, and weaknesses of these LLMs, informing their practical applications within the medical domain.

Tianyang Zhong, Zhengliang Liu, Yi Pan et al.

This comprehensive study evaluates the performance of OpenAI's o1-preview large language model across a diverse array of complex reasoning tasks, spanning multiple domains, including computer science, mathematics, natural sciences, medicine, linguistics, and social sciences. Through rigorous testing, o1-preview demonstrated remarkable capabilities, often achieving human-level or superior performance in areas ranging from coding challenges to scientific reasoning and from language processing to creative problem-solving. Key findings include: -83.3% success rate in solving complex competitive programming problems, surpassing many human experts. -Superior ability in generating coherent and accurate radiology reports, outperforming other evaluated models. -100% accuracy in high school-level mathematical reasoning tasks, providing detailed step-by-step solutions. -Advanced natural language inference capabilities across general and specialized domains like medicine. -Impressive performance in chip design tasks, outperforming specialized models in areas such as EDA script generation and bug analysis. -Remarkable proficiency in anthropology and geology, demonstrating deep understanding and reasoning in these specialized fields. -Strong capabilities in quantitative investing. O1 has comprehensive financial knowledge and statistical modeling skills. -Effective performance in social media analysis, including sentiment analysis and emotion recognition. The model excelled particularly in tasks requiring intricate reasoning and knowledge integration across various fields. While some limitations were observed, including occasional errors on simpler problems and challenges with certain highly specialized concepts, the overall results indicate significant progress towards artificial general intelligence.

Tianyang Zhong, Yaonai Wei, Li Yang et al.

Large language models (LLMs) such as ChatGPT have recently demonstrated significant potential in mathematical abilities, providing valuable reasoning paradigm consistent with human natural language. However, LLMs currently have difficulty in bridging perception, language understanding and reasoning capabilities due to incompatibility of the underlying information flow among them, making it challenging to accomplish tasks autonomously. On the other hand, abductive learning (ABL) frameworks for integrating the two abilities of perception and reasoning has seen significant success in inverse decipherment of incomplete facts, but it is limited by the lack of semantic understanding of logical reasoning rules and the dependence on complicated domain knowledge representation. This paper presents a novel method (ChatABL) for integrating LLMs into the ABL framework, aiming at unifying the three abilities in a more user-friendly and understandable manner. The proposed method uses the strengths of LLMs' understanding and logical reasoning to correct the incomplete logical facts for optimizing the performance of perceptual module, by summarizing and reorganizing reasoning rules represented in natural language format. Similarly, perceptual module provides necessary reasoning examples for LLMs in natural language format. The variable-length handwritten equation deciphering task, an abstract expression of the Mayan calendar decoding, is used as a testbed to demonstrate that ChatABL has reasoning ability beyond most existing state-of-the-art methods, which has been well supported by comparative studies. To our best knowledge, the proposed ChatABL is the first attempt to explore a new pattern for further approaching human-level cognitive ability via natural language interaction with ChatGPT.

Hao Chen, Wei Zhao, Yingli Li et al.

Medical image analysis is crucial in modern radiological diagnostics, especially given the exponential growth in medical imaging data. The demand for automated report generation systems has become increasingly urgent. While prior research has mainly focused on using machine learning and multimodal language models for 2D medical images, the generation of reports for 3D medical images has been less explored due to data scarcity and computational complexities. This paper introduces 3D-CT-GPT, a Visual Question Answering (VQA)-based medical visual language model specifically designed for generating radiology reports from 3D CT scans, particularly chest CTs. Extensive experiments on both public and private datasets demonstrate that 3D-CT-GPT significantly outperforms existing methods in terms of report accuracy and quality. Although current methods are few, including the partially open-source CT2Rep and the open-source M3D, we ensured fair comparison through appropriate data conversion and evaluation methodologies. Experimental results indicate that 3D-CT-GPT enhances diagnostic accuracy and report coherence, establishing itself as a robust solution for clinical radiology report generation. Future work will focus on expanding the dataset and further optimizing the model to enhance its performance and applicability.

Jiaqi Wang, Hanqi Jiang, Yiheng Liu et al.

In an era defined by the explosive growth of data and rapid technological advancements, Multimodal Large Language Models (MLLMs) stand at the forefront of artificial intelligence (AI) systems. Designed to seamlessly integrate diverse data types-including text, images, videos, audio, and physiological sequences-MLLMs address the complexities of real-world applications far beyond the capabilities of single-modality systems. In this paper, we systematically sort out the applications of MLLM in multimodal tasks such as natural language, vision, and audio. We also provide a comparative analysis of the focus of different MLLMs in the tasks, and provide insights into the shortcomings of current MLLMs, and suggest potential directions for future research. Through these discussions, this paper hopes to provide valuable insights for the further development and application of MLLM.

Yaonai Wei, Tuo Zhang, Han Zhang et al.

Over decades, neuroscience has accumulated a wealth of research results in the text modality that can be used to explore cognitive processes. Meta-analysis is a typical method that successfully establishes a link from text queries to brain activation maps using these research results, but it still relies on an ideal query environment. In practical applications, text queries used for meta-analyses may encounter issues such as semantic redundancy and ambiguity, resulting in an inaccurate mapping to brain images. On the other hand, large language models (LLMs) like ChatGPT have shown great potential in tasks such as context understanding and reasoning, displaying a high degree of consistency with human natural language. Hence, LLMs could improve the connection between text modality and neuroscience, resolving existing challenges of meta-analyses. In this study, we propose a method called Chat2Brain that combines LLMs to basic text-2-image model, known as Text2Brain, to map open-ended semantic queries to brain activation maps in data-scarce and complex query environments. By utilizing the understanding and reasoning capabilities of LLMs, the performance of the mapping model is optimized by transferring text queries to semantic queries. We demonstrate that Chat2Brain can synthesize anatomically plausible neural activation patterns for more complex tasks of text queries.

Tianyang Zhong, Wei Zhao, Yutong Zhang et al.

Radiology report generation, as a key step in medical image analysis, is critical to the quantitative analysis of clinically informed decision-making levels. However, complex and diverse radiology reports with cross-source heterogeneity pose a huge generalizability challenge to the current methods under massive data volume, mainly because the style and normativity of radiology reports are obviously distinctive among institutions, body regions inspected and radiologists. Recently, the advent of large language models (LLM) offers great potential for recognizing signs of health conditions. To resolve the above problem, we collaborate with the Second Xiangya Hospital in China and propose ChatRadio-Valuer based on the LLM, a tailored model for automatic radiology report generation that learns generalizable representations and provides a basis pattern for model adaptation in sophisticated analysts' cases. Specifically, ChatRadio-Valuer is trained based on the radiology reports from a single institution by means of supervised fine-tuning, and then adapted to disease diagnosis tasks for human multi-system evaluation (i.e., chest, abdomen, muscle-skeleton, head, and maxillofacial $\&$ neck) from six different institutions in clinical-level events. The clinical dataset utilized in this study encompasses a remarkable total of \textbf{332,673} observations. From the comprehensive results on engineering indicators, clinical efficacy and deployment cost metrics, it can be shown that ChatRadio-Valuer consistently outperforms state-of-the-art models, especially ChatGPT (GPT-3.5-Turbo) and GPT-4 et al., in terms of the diseases diagnosis from radiology reports. ChatRadio-Valuer provides an effective avenue to boost model generalization performance and alleviate the annotation workload of experts to enable the promotion of clinical AI applications in radiology reports.

Zhengliang Liu, Hanqi Jiang, Tianyang Zhong et al.

In this paper, we present a large-scale evaluation probing GPT-4V's capabilities and limitations for biomedical image analysis. GPT-4V represents a breakthrough in artificial general intelligence (AGI) for computer vision, with applications in the biomedical domain. We assess GPT-4V's performance across 16 medical imaging categories, including radiology, oncology, ophthalmology, pathology, and more. Tasks include modality recognition, anatomy localization, disease diagnosis, report generation, and lesion detection. The extensive experiments provide insights into GPT-4V's strengths and weaknesses. Results show GPT-4V's proficiency in modality and anatomy recognition but difficulty with disease diagnosis and localization. GPT-4V excels at diagnostic report generation, indicating strong image captioning skills. While promising for biomedical imaging AI, GPT-4V requires further enhancement and validation before clinical deployment. We emphasize responsible development and testing for trustworthy integration of biomedical AGI. This rigorous evaluation of GPT-4V on diverse medical images advances understanding of multimodal large language models (LLMs) and guides future work toward impactful healthcare applications.

Huawen Hu, Enze Shi, Chenxi Yue et al.

Human-in-the-loop reinforcement learning integrates human expertise to accelerate agent learning and provide critical guidance and feedback in complex fields. However, many existing approaches focus on single-agent tasks and require continuous human involvement during the training process, significantly increasing the human workload and limiting scalability. In this paper, we propose HARP (Human-Assisted Regrouping with Permutation Invariant Critic), a multi-agent reinforcement learning framework designed for group-oriented tasks. HARP integrates automatic agent regrouping with strategic human assistance during deployment, enabling and allowing non-experts to offer effective guidance with minimal intervention. During training, agents dynamically adjust their groupings to optimize collaborative task completion. When deployed, they actively seek human assistance and utilize the Permutation Invariant Group Critic to evaluate and refine human-proposed groupings, allowing non-expert users to contribute valuable suggestions. In multiple collaboration scenarios, our approach is able to leverage limited guidance from non-experts and enhance performance. The project can be found at https://github.com/huawen-hu/HARP.

Yutong Zhang, Yi Pan, Tianyang Zhong et al.

Medical images and radiology reports are crucial for diagnosing medical conditions, highlighting the importance of quantitative analysis for clinical decision-making. However, the diversity and cross-source heterogeneity of these data challenge the generalizability of current data-mining methods. Multimodal large language models (MLLMs) have recently transformed many domains, significantly affecting the medical field. Notably, Gemini-Vision-series (Gemini) and GPT-4-series (GPT-4) models have epitomized a paradigm shift in Artificial General Intelligence (AGI) for computer vision, showcasing their potential in the biomedical domain. In this study, we evaluated the performance of the Gemini, GPT-4, and 4 popular large models for an exhaustive evaluation across 14 medical imaging datasets, including 5 medical imaging categories (dermatology, radiology, dentistry, ophthalmology, and endoscopy), and 3 radiology report datasets. The investigated tasks encompass disease classification, lesion segmentation, anatomical localization, disease diagnosis, report generation, and lesion detection. Our experimental results demonstrated that Gemini-series models excelled in report generation and lesion detection but faces challenges in disease classification and anatomical localization. Conversely, GPT-series models exhibited proficiency in lesion segmentation and anatomical localization but encountered difficulties in disease diagnosis and lesion detection. Additionally, both the Gemini series and GPT series contain models that have demonstrated commendable generation efficiency. While both models hold promise in reducing physician workload, alleviating pressure on limited healthcare resources, and fostering collaboration between clinical practitioners and artificial intelligence technologies, substantial enhancements and comprehensive validations remain imperative before clinical deployment.

Jialiang Yang, Bin Xia, Ruihang Chu et al.

Rapid advances in audio-video (AV) generation have enabled high-fidelity synthesis with synchronized sound, particularly for human-related scenarios involving speech and interactions. Yet evaluation for AV generation remains at an early stage, with only a few coarse-grained benchmarks for human-related scenarios and relying on limited preset evaluations with generic multimodal LLMs, leading to inaccurate assessments of model capabilities. To address these issues, we introduce AVBench, a fully automated benchmark tailored for human-centric AV generation. AVBench is built on two key designs for comprehensive and accurate evaluation: (i) Human-centric and fine-grained metrics. AVBench integrates ten evaluation dimensions designed for human-centered real-world scenarios, covering visual quality, audio quality, and multi-level consistency across modalities. These practical metrics capture human-related details that existing benchmarks often overlook. (ii) Specialized evaluators via preference learning. To address the lack of specialized training data, we construct large-scale supervision by transforming real-world videos into diverse training pairs with controlled perturbations. After fine-tuning on this high-quality dataset, the evaluators learn to reliably detect subtle cross-modal inconsistencies. Crucially, instead of producing discrete textual judgment, AVBench derives continuous evaluation scores from the model's prediction confidence on binary decisions. This probabilistic scoring mechanism enables a more reliable assessment than traditional VQA-style evaluation and aligns closely with human judgment. Taken together, AVBench offers automated evaluation for AV generation, demonstrates strong potential for data filtering, and serves as a differentiable reward signal for Reinforcement Learning from Human Feedback (RLHF).

Haoyang Wang, Ruishan Guo, Pengtao Ma et al.

With the increasing complexity of mobile device applications, these devices are evolving toward high agility. This shift imposes new demands on mobile sensing, particularly in achieving high-accuracy and low-latency. Event-based vision has emerged as a disruptive paradigm, offering high temporal resolution and low latency, making it well-suited for high-accuracy and low-latency sensing tasks on high-agility platforms. However, the presence of substantial noisy events, lack of stable, persistent semantic information, and large data volume pose challenges for event-based data processing on resource-constrained mobile devices. This paper surveys the literature from 2014 to 2025 and presents a comprehensive overview of event-based mobile sensing, encompassing its fundamental principles, event \textit{abstraction} methods, \textit{algorithm} advancements, and both hardware and software \textit{acceleration} strategies. We discuss key \textit{applications} of event cameras in mobile sensing, including visual odometry, object tracking, optical flow, and 3D reconstruction, while highlighting challenges associated with event data processing, sensor fusion, and real-time deployment. Furthermore, we outline future research directions, such as improving the event camera with advanced optics, leveraging neuromorphic computing for efficient processing, and integrating bio-inspired algorithms. To support ongoing research, we provide an open-source \textit{Online Sheet} with recent developments. We hope this survey serves as a reference, facilitating the adoption of event-based vision across diverse applications.

Jiaqi Wang, Huan Zhao, Zhenyuan Yang et al.

In this paper, we review legal testing methods based on Large Language Models (LLMs), using the OPENAI o1 model as a case study to evaluate the performance of large models in applying legal provisions. We compare current state-of-the-art LLMs, including open-source, closed-source, and legal-specific models trained specifically for the legal domain. Systematic tests are conducted on English and Chinese legal cases, and the results are analyzed in depth. Through systematic testing of legal cases from common law systems and China, this paper explores the strengths and weaknesses of LLMs in understanding and applying legal texts, reasoning through legal issues, and predicting judgments. The experimental results highlight both the potential and limitations of LLMs in legal applications, particularly in terms of challenges related to the interpretation of legal language and the accuracy of legal reasoning. Finally, the paper provides a comprehensive analysis of the advantages and disadvantages of various types of models, offering valuable insights and references for the future application of AI in the legal field.

Yiheng Liu, Hao He, Tianle Han et al.

The introduction of ChatGPT has led to a significant increase in the utilization of Large Language Models (LLMs) for addressing downstream tasks. There's an increasing focus on cost-efficient training and deployment within this context. Low-cost training and deployment of LLMs represent the future development trend. This paper reviews the evolution of large language model training techniques and inference deployment technologies aligned with this emerging trend. The discussion on training includes various aspects, including data preprocessing, training architecture, pre-training tasks, parallel training, and relevant content related to model fine-tuning. On the inference side, the paper covers topics such as model compression, parallel computation, memory scheduling, and structural optimization. It also explores LLMs' utilization and provides insights into their future development.

Tianyang Zhong, Zhenyuan Yang, Zhengliang Liu et al.

Low-resource languages serve as invaluable repositories of human history, embodying cultural evolution and intellectual diversity. Despite their significance, these languages face critical challenges, including data scarcity and technological limitations, which hinder their comprehensive study and preservation. Recent advancements in large language models (LLMs) offer transformative opportunities for addressing these challenges, enabling innovative methodologies in linguistic, historical, and cultural research. This study systematically evaluates the applications of LLMs in low-resource language research, encompassing linguistic variation, historical documentation, cultural expressions, and literary analysis. By analyzing technical frameworks, current methodologies, and ethical considerations, this paper identifies key challenges such as data accessibility, model adaptability, and cultural sensitivity. Given the cultural, historical, and linguistic richness inherent in low-resource languages, this work emphasizes interdisciplinary collaboration and the development of customized models as promising avenues for advancing research in this domain. By underscoring the potential of integrating artificial intelligence with the humanities to preserve and study humanity's linguistic and cultural heritage, this study fosters global efforts towards safeguarding intellectual diversity.

Huan Zhao, Qian Ling, Yi Pan et al.

In recent years, pre-trained large language models (LLMs) have achieved tremendous success in the field of Natural Language Processing (NLP). Prior studies have primarily focused on general and generic domains, with relatively less research on specialized LLMs in the medical field. The specialization and high accuracy requirements for diagnosis in the medical field, as well as the challenges in collecting large-scale data, have constrained the application and development of LLMs in medical scenarios. In the field of ophthalmology, clinical diagnosis mainly relies on doctors' interpretation of reports and making diagnostic decisions. In order to take advantage of LLMs to provide decision support for doctors, we collected three modalities of ophthalmic report data and fine-tuned the LLaMA2 model, successfully constructing an LLM termed the "Ophtha-LLaMA2" specifically tailored for ophthalmic disease diagnosis. Inference test results show that even with a smaller fine-tuning dataset, Ophtha-LLaMA2 performs significantly better in ophthalmic diagnosis compared to other LLMs. It demonstrates that the Ophtha-LLaMA2 exhibits satisfying accuracy and efficiency in ophthalmic disease diagnosis, making it a valuable tool for ophthalmologists to provide improved diagnostic support for patients. This research provides a useful reference for the application of LLMs in the field of ophthalmology, while showcasing the immense potential and prospects in this domain.

Peng Shu, Junhao Chen, Zhengliang Liu et al.

Large Language Models (LLMs) have demonstrated remarkable success across a wide range of tasks and domains. However, their performance in low-resource language translation, particularly when translating into these languages, remains underexplored. This gap poses significant challenges, as linguistic barriers hinder the cultural preservation and development of minority communities. To address this issue, this paper introduces a novel retrieval-based method that enhances translation quality for low-resource languages by focusing on key terms, which involves translating keywords and retrieving corresponding examples from existing data. To evaluate the effectiveness of this method, we conducted experiments translating from English into three low-resource languages: Cherokee, a critically endangered indigenous language of North America; Tibetan, a historically and culturally significant language in Asia; and Manchu, a language with few remaining speakers. Our comparison with the zero-shot performance of GPT-4o and LLaMA 3.1 405B, highlights the significant challenges these models face when translating into low-resource languages. In contrast, our retrieval-based method shows promise in improving both word-level accuracy and overall semantic understanding by leveraging existing resources more effectively.

Shaochen Xu, Yifan Zhou, Zhengliang Liu et al.

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context demonstrations and those with specialized medical fine-tuning, have demonstrated strong performance in medical language processing but struggle with real-time adaptability, multi-step reasoning, and handling complex medical tasks. Agent-based AI systems address these limitations by incorporating reasoning traces, tool selection based on context, knowledge retrieval, and both short- and long-term memory. These additional features enable the medical AI agent to handle complex medical scenarios where decision-making should be built on real-time interaction with the environment. Therefore, unlike conventional model-based approaches that treat medical queries as isolated questions, medical AI agents approach them as complex tasks and behave more like human doctors. In this paper, we study the choice of the backbone LLM for medical AI agents, which is the foundation for the agent's overall reasoning and action generation. In particular, we consider the emergent o1 model and examine its impact on agents' reasoning, tool-use adaptability, and real-time information retrieval across diverse clinical scenarios, including high-stakes settings such as intensive care units (ICUs). Our findings demonstrate o1's ability to enhance diagnostic accuracy and consistency, paving the way for smarter, more responsive AI tools that support better patient outcomes and decision-making efficacy in clinical practice.

Shizhe Liang, Wei Zhang, Tianyang Zhong et al.

This paper presents a comprehensive overview on the applications of artificial intelligence (AI) in mathematical research, highlighting the transformative role AI has begun to play in this domain. Traditionally, AI advancements have heavily relied on theoretical foundations provided by mathematics and statistics. However, recent developments in AI, particularly in reinforcement learning (RL) and large language models (LLMs), have demonstrated the potential for AI to contribute back to mathematics by offering flexible algorithmic frameworks and powerful inductive reasoning capabilities that support various aspects of mathematical research. This survey aims to establish a bridge between AI and mathematics, providing insights into the mutual benefits and fostering deeper interdisciplinary understanding. In particular, we argue that while current AI and LLMs may struggle with complex deductive reasoning, their "inherent creativity", the ability to generate outputs at high throughput based on recognition of shallow patterns, holds significant potential to support and inspire mathematical research. This creative capability, often overlooked, could be the key to unlocking new perspectives and methodologies in mathematics. Furthermore, we address the lack of cross-disciplinary communication: mathematicians may not fully comprehend the latest advances in AI, while AI researchers frequently prioritize benchmark performance over real-world applications in frontier mathematical research. This paper seeks to close that gap, offering a detailed exploration of AI fundamentals, its strengths, and its emerging applications in the mathematical sciences.

Zhenyuan Yang, Zhengliang Liu, Jing Zhang et al.

This study examines the capabilities of advanced Large Language Models (LLMs), particularly the o1 model, in the context of literary analysis. The outputs of these models are compared directly to those produced by graduate-level human participants. By focusing on two Nobel Prize-winning short stories, 'Nine Chapters' by Han Kang, the 2024 laureate, and 'Friendship' by Jon Fosse, the 2023 laureate, the research explores the extent to which AI can engage with complex literary elements such as thematic analysis, intertextuality, cultural and historical contexts, linguistic and structural innovations, and character development. Given the Nobel Prize's prestige and its emphasis on cultural, historical, and linguistic richness, applying LLMs to these works provides a deeper understanding of both human and AI approaches to interpretation. The study uses qualitative and quantitative evaluations of coherence, creativity, and fidelity to the text, revealing the strengths and limitations of AI in tasks typically reserved for human expertise. While LLMs demonstrate strong analytical capabilities, particularly in structured tasks, they often fall short in emotional nuance and coherence, areas where human interpretation excels. This research underscores the potential for human-AI collaboration in the humanities, opening new opportunities in literary studies and beyond.