Sudhanya Chatterjee

Hemant Kumar Aggarwal, Sudhanya Chatterjee, Dattesh Shanbhag et al.

Single-shot magnetic resonance (MR) imaging acquires the entire k-space data in a single shot and it has various applications in whole-body imaging. However, the long acquisition time for the entire k-space in single-shot fast spin echo (SSFSE) MR imaging poses a challenge, as it introduces T2-blur in the acquired images. This study aims to enhance the reconstruction quality of SSFSE MR images by (a) optimizing the trajectory for measuring the k-space, (b) acquiring fewer samples to speed up the acquisition process, and (c) reducing the impact of T2-blur. The proposed method adheres to physics constraints due to maximum gradient strength and slew-rate available while optimizing the trajectory within an end-to-end learning framework. Experiments were conducted on publicly available fastMRI multichannel dataset with 8-fold and 16-fold acceleration factors. An experienced radiologist's evaluation on a five-point Likert scale indicates improvements in the reconstruction quality as the ACL fibers are sharper than comparative methods.

Sneha Sree C., Dattesh Shanbhag, Sudhanya Chatterjee

Medical image registration is critical for aligning anatomical structures across imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound. Among existing techniques, non-rigid registration (NRR) is particularly challenging due to the need to capture complex anatomical deformations caused by physiological processes like respiration or contrast-induced signal variations. Traditional NRR methods, while theoretically robust, often require extensive parameter tuning and incur high computational costs, limiting their use in real-time clinical workflows. Recent deep learning (DL)-based approaches have shown promise; however, their dependence on task-specific retraining restricts scalability and adaptability in practice. These limitations underscore the need for efficient, generalizable registration frameworks capable of handling heterogeneous imaging contexts. In this work, we introduce a novel AI-driven framework for 3D non-rigid registration that generalizes across multiple imaging modalities and anatomical regions. Unlike conventional methods that rely on application-specific models, our approach eliminates anatomy- or modality-specific customization, enabling streamlined integration into diverse clinical environments.