Hong Su

Renqi Chen, Haoyang Su, Shixiang Tang

The Segment Anything Model (SAM) has emerged as a powerful visual foundation model for image segmentation. However, adapting SAM to specific downstream tasks, such as medical and agricultural imaging, remains a significant challenge. To address this, Low-Rank Adaptation (LoRA) and its variants have been widely employed to enhancing SAM's adaptation performance on diverse domains. Despite advancements, a critical question arises: can we integrate inductive bias into the model? This is particularly relevant since the Transformer encoder in SAM inherently lacks spatial priors within image patches, potentially hindering the acquisition of high-level semantic information. In this paper, we propose NAS-LoRA, a new Parameter-Efficient Fine-Tuning (PEFT) method designed to bridge the semantic gap between pre-trained SAM and specialized domains. Specifically, NAS-LoRA incorporates a lightweight Neural Architecture Search (NAS) block between the encoder and decoder components of LoRA to dynamically optimize the prior knowledge integrated into weight updates. Furthermore, we propose a stage-wise optimization strategy to help the ViT encoder balance weight updates and architectural adjustments, facilitating the gradual learning of high-level semantic information. Various Experiments demonstrate our NAS-LoRA improves existing PEFT methods, while reducing training cost by 24.14% without increasing inference cost, highlighting the potential of NAS in enhancing PEFT for visual foundation models.

Chunxia Ren, Ning Zhu, Yue Lai et al.

Dentocraniofacial hard tissue defects profoundly affect patients' physiological functions, facial aesthetics, and psychological well-being, posing significant challenges for precise reconstruction. Current deep learning models are limited to single-tissue scenarios and modality-specific imaging inputs, resulting in poor generalizability and trade-offs between anatomical fidelity, computational efficiency, and cross-tissue adaptability. Here we introduce UniDCF, a unified framework capable of reconstructing multiple dentocraniofacial hard tissues through multimodal fusion encoding of point clouds and multi-view images. By leveraging the complementary strengths of each modality and incorporating a score-based denoising module to refine surface smoothness, UniDCF overcomes the limitations of prior single-modality approaches. We curated the largest multimodal dataset, comprising intraoral scans, CBCT, and CT from 6,609 patients, resulting in 54,555 annotated instances. Evaluations demonstrate that UniDCF outperforms existing state-of-the-art methods in terms of geometric precision, structural completeness, and spatial accuracy. Clinical simulations indicate UniDCF reduces reconstruction design time by 99% and achieves clinician-rated acceptability exceeding 94%. Overall, UniDCF enables rapid, automated, and high-fidelity reconstruction, supporting personalized and precise restorative treatments, streamlining clinical workflows, and enhancing patient outcomes.