Tianyu Zhao

Tianyu Zhao, Yue Zhou, Ruijun Shi et al.

The detection of Extreme Mass Ratio Inspirals (EMRIs) is intricate due to their complex waveforms, extended duration, and low signal-to-noise ratio (SNR), making them more challenging to be identified compared to compact binary coalescences. While matched filtering-based techniques are known for their computational demands, existing deep learning-based methods primarily handle time-domain data and are often constrained by data duration and SNR. In addition, most existing work ignores time-delay interferometry (TDI) and applies the long-wavelength approximation in detector response calculations, thus limiting their ability to handle laser frequency noise. In this study, we introduce DECODE, an end-to-end model focusing on EMRI signal detection by sequence modeling in the frequency domain. Centered around a dilated causal convolutional neural network, trained on synthetic data considering TDI-1.5 detector response, DECODE can efficiently process a year's worth of multichannel TDI data with an SNR of around 50. We evaluate our model on 1-year data with accumulated SNR ranging from 50 to 120 and achieve a true positive rate of 96.3% at a false positive rate of 1%, keeping an inference time of less than 0.01 seconds. With the visualization of three showcased EMRI signals for interpretability and generalization, DECODE exhibits strong potential for future space-based gravitational wave data analyses.

Tianyu Zhao, Junping Du, Yingxia Shao et al.

Federated learning is a distributed machine learning technology, which realizes the balance between data privacy protection and data sharing computing. To protect data privacy, feder-ated learning learns shared models by locally executing distributed training on participating devices and aggregating local models into global models. There is a problem in federated learning, that is, the negative impact caused by the non-independent and identical distribu-tion of data across different user terminals. In order to alleviate this problem, this paper pro-poses a strengthened federation aggregation method based on adaptive OPTICS clustering. Specifically, this method perceives the clustering environment as a Markov decision process, and models the adjustment process of parameter search direction, so as to find the best clus-tering parameters to achieve the best federated aggregation method. The core contribution of this paper is to propose an adaptive OPTICS clustering algorithm for federated learning. The algorithm combines OPTICS clustering and adaptive learning technology, and can effective-ly deal with the problem of non-independent and identically distributed data across different user terminals. By perceiving the clustering environment as a Markov decision process, the goal is to find the best parameters of the OPTICS cluster without artificial assistance, so as to obtain the best federated aggregation method and achieve better performance. The reliability and practicability of this method have been verified on the experimental data, and its effec-tiveness and superiority have been proved.

Yunfei Fan, Tianyu Zhao, Guidong Wang

Accuracy and computational efficiency are the most important metrics to Visual Inertial Navigation System (VINS). The existing VINS algorithms with either high accuracy or low computational complexity, are difficult to provide the high precision localization in resource-constrained devices. To this end, we propose a novel filter-based VINS framework named SchurVINS, which could guarantee both high accuracy by building a complete residual model and low computational complexity with Schur complement. Technically, we first formulate the full residual model where Gradient, Hessian and observation covariance are explicitly modeled. Then Schur complement is employed to decompose the full model into ego-motion residual model and landmark residual model. Finally, Extended Kalman Filter (EKF) update is implemented in these two models with high efficiency. Experiments on EuRoC and TUM-VI datasets show that our method notably outperforms state-of-the-art (SOTA) methods in both accuracy and computational complexity. The experimental code of SchurVINS is available at https://github.com/bytedance/SchurVINS.

Zenan Huang, Yihong Zhuang, Guoshan Lu et al.

Reinforcement Learning from Verifiable Rewards (RLVR) has emerged as a powerful paradigm for enhancing Large Language Models (LLMs), exemplified by the success of OpenAI's o-series. In RLVR, rewards are derived from verifiable signals-such as passing unit tests in code generation or matching correct answers in mathematical reasoning. While effective, this requirement largely confines RLVR to domains with automatically checkable outcomes. To overcome this, we extend the RLVR paradigm to open-ended tasks by integrating rubric-based rewards, where carefully designed rubrics serve as structured, model-interpretable criteria for automatic scoring of subjective outputs. We construct, to our knowledge, the largest rubric reward system to date, with over 10,000 rubrics from humans, LLMs, or a hybrid human-LLM collaboration. Implementing rubric-based RL is challenging; we tackle these issues with a clear framework and present an open-sourced Qwen-30B-A3B model with notable gains: 1) With only 5K+ samples, our system improves by +5.2% on open-ended benchmarks (especially humanities), outperforming a 671B DeepSeek-V3 model by +2.4%, while preserving general and reasoning abilities. 2) Our method provides fine-grained stylistic control, using rubrics as anchors to mitigate the "AI-like" tone and produce more human-like, expressive responses. We share key lessons in rubric construction, data selection, and training, and discuss limitations and future releases.

Huayang Li, Tianyu Zhao, Deng Cai et al.

In-context learning is fundamental to modern Large Language Models (LLMs); however, prevailing architectures impose a rigid and fixed contextual structure by assigning linear or constant positional indices. Drawing on Cognitive Load Theory (CLT), we argue that this uninformative structure increases extraneous cognitive load, consuming finite working memory capacity that should be allocated to deep reasoning and attention allocation. To address this, we propose RePo, a novel mechanism that reduces extraneous load via context re-positioning. Unlike standard approaches, RePo utilizes a differentiable module, $f_φ$, to assign token positions that capture contextual dependencies, rather than replying on pre-defined order. By continually pre-training on the OLMo-2 1B & 7B models, we demonstrate that RePo consistently enhances performance on tasks involving noisy contexts, structured data, and longer context length, while maintaining competitive performance on general short-context tasks. Detailed analysis reveals that RePo successfully allocate higher attention to distant but relevant information, assign positions in dense and non-linear space, and capture the intrinsic structure of the input context. We will open-source the code and model weights. Our code is at https://github.com/SakanaAI/repo.

Zehao Dong, Qihang Zhao, Philip R. O. Payne et al.

Biomarker identification is critical for precise disease diagnosis and understanding disease pathogenesis in omics data analysis, like using fold change and regression analysis. Graph neural networks (GNNs) have been the dominant deep learning model for analyzing graph-structured data. However, we found two major limitations of existing GNNs in omics data analysis, i.e., limited-prediction (diagnosis) accuracy and limited-reproducible biomarker identification capacity across multiple datasets. The root of the challenges is the unique graph structure of biological signaling pathways, which consists of a large number of targets and intensive and complex signaling interactions among these targets. To resolve these two challenges, in this study, we presented a novel GNN model architecture, named PathFormer, which systematically integrate signaling network, priori knowledge and omics data to rank biomarkers and predict disease diagnosis. In the comparison results, PathFormer outperformed existing GNN models significantly in terms of highly accurate prediction capability ( 30% accuracy improvement in disease diagnosis compared with existing GNN models) and high reproducibility of biomarker ranking across different datasets. The improvement was confirmed using two independent Alzheimer's Disease (AD) and cancer transcriptomic datasets. The PathFormer model can be directly applied to other omics data analysis studies.

Zehao Dong, Yixin Chen, Hiram Gay et al.

Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between DVHs in radiotherapy plans and organs-at-risk (OAR) and planning target volume (PTV) has been well established. This study explores the potential of deep learning models for predicting DVHs using images and subsequent human intervention facilitated by a large-language model (LLM) to enhance the planning quality. We propose a pipeline to convert unstructured images to a structured graph consisting of image-patch nodes and dose nodes. A novel Dose Graph Neural Network (DoseGNN) model is developed for predicting DVHs from the structured graph. The proposed DoseGNN is enhanced with the LLM to encode massive knowledge from prescriptions and interactive instructions from clinicians. In this study, we introduced an online human-AI collaboration (OHAC) system as a practical implementation of the concept proposed for the automation of intensity-modulated radiotherapy (IMRT) planning. In comparison to the widely-employed DL models used in radiotherapy, DoseGNN achieved mean square errors that were 80$\%$, 76$\%$ and 41.0$\%$ of those predicted by Swin U-Net Transformer, 3D U-Net CNN and vanilla MLP, respectively. Moreover, the LLM-empowered DoseGNN model facilitates seamless adjustment to treatment plans through interaction with clinicians using natural language.

Zehao Dong, Muhan Zhang, Philip R. O. Payne et al.

The expressivity of Graph Neural Networks (GNNs) has been studied broadly in recent years to reveal the design principles for more powerful GNNs. Graph canonization is known as a typical approach to distinguish non-isomorphic graphs, yet rarely adopted when developing expressive GNNs. This paper proposes to maximize the expressivity of GNNs by graph canonization, then the power of such GNNs is studies from the perspective of model stability. A stable GNN will map similar graphs to close graph representations in the vectorial space, and the stability of GNNs is critical to generalize their performance to unseen graphs. We theoretically reveal the trade-off of expressivity and stability in graph-canonization-enhanced GNNs. Then we introduce a notion of universal graph canonization as the general solution to address the trade-off and characterize a widely applicable sufficient condition to solve the universal graph canonization. A comprehensive set of experiments demonstrates the effectiveness of the proposed method. In many popular graph benchmark datasets, graph canonization successfully enhances GNNs and provides highly competitive performance, indicating the capability and great potential of proposed method in general graph representation learning. In graph datasets where the sufficient condition holds, GNNs enhanced by universal graph canonization consistently outperform GNN baselines and successfully improve the SOTA performance up to $31\%$, providing the optimal solution to numerous challenging real-world graph analytical tasks like gene network representation learning in bioinformatics.

Zhuangzhuang Zhang, Tianyu Zhao, Hiram Gay et al.

In radiotherapy planning, manual contouring is labor-intensive and time-consuming. Accurate and robust automated segmentation models improve the efficiency and treatment outcome. We aim to develop a novel hybrid deep learning approach, combining convolutional neural networks (CNNs) and the self-attention mechanism, for rapid and accurate multi-organ segmentation on head and neck computed tomography (CT) images. Head and neck CT images with manual contours of 115 patients were retrospectively collected and used. We set the training/validation/testing ratio to 81/9/25 and used the 10-fold cross-validation strategy to select the best model parameters. The proposed hybrid model segmented ten organs-at-risk (OARs) altogether for each case. The performance of the model was evaluated by three metrics, i.e., the Dice Similarity Coefficient (DSC), Hausdorff distance 95% (HD95), and mean surface distance (MSD). We also tested the performance of the model on the Head and Neck 2015 challenge dataset and compared it against several state-of-the-art automated segmentation algorithms. The proposed method generated contours that closely resemble the ground truth for ten OARs. Our results of the new Weaving Attention U-net demonstrate superior or similar performance on the segmentation of head and neck CT images.

Zhuangzhuang Zhang, Tianyu Zhao, Hiram Gay et al.

Automated segmentation can assist radiotherapy treatment planning by saving manual contouring efforts and reducing intra-observer and inter-observer variations. The recent development of deep learning approaches has revoluted medical data processing, including semantic segmentation, by dramatically improving performance. However, training effective deep learning models usually require a large amount of high-quality labeled data, which are often costly to collect. We developed a novel semi-supervised adversarial deep learning approach for 3D pelvic CT image semantic segmentation. Unlike supervised deep learning methods, the new approach can utilize both annotated and un-annotated data for training. It generates un-annotated synthetic data by a data augmentation scheme using generative adversarial networks (GANs). We applied the new approach to segmenting multiple organs in male pelvic CT images, where CT images without annotations and GAN-synthesized un-annotated images were used in semi-supervised learning. Experimental results, evaluated by three metrics (Dice similarity coefficient, average Hausdorff distance, and average surface Hausdorff distance), showed that the new method achieved either comparable performance with substantially fewer annotated images or better performance with the same amount of annotated data, outperforming the existing state-of-the-art methods.