Michael King

Akshay Iyer, Clifford Lindsay, Hendrik Pretorius et al.

In this work, we develop a neural network-based method to convert a noisy motion signal generated from segmenting rebinned list-mode cardiac SPECT images, to that of a high-quality surrogate signal, such as those seen from external motion tracking systems (EMTs). This synthetic surrogate will be used as input to our pre-existing motion correction technique developed for EMT surrogate signals. In our method, we test two families of neural networks to translate noisy internal motion to external surrogate: 1) fully connected networks and 2) convolutional neural networks. Our dataset consists of cardiac perfusion SPECT acquisitions for which cardiac motion was estimated (input: center-of-count-mass - COM signals) in conjunction with a respiratory surrogate motion signal acquired using a commercial Vicon Motion Tracking System (GT: EMT signals). We obtained an average R-score of 0.76 between the predicted surrogate and the EMT signal. Our goal is to lay a foundation to guide the optimization of neural networks for respiratory motion correction from SPECT without the need for an EMT.

Jane X. Wang, Michael King, Nicolas Porcel et al.

There has been rapidly growing interest in meta-learning as a method for increasing the flexibility and sample efficiency of reinforcement learning. One problem in this area of research, however, has been a scarcity of adequate benchmark tasks. In general, the structure underlying past benchmarks has either been too simple to be inherently interesting, or too ill-defined to support principled analysis. In the present work, we introduce a new benchmark for meta-RL research, emphasizing transparency and potential for in-depth analysis as well as structural richness. Alchemy is a 3D video game, implemented in Unity, which involves a latent causal structure that is resampled procedurally from episode to episode, affording structure learning, online inference, hypothesis testing and action sequencing based on abstract domain knowledge. We evaluate a pair of powerful RL agents on Alchemy and present an in-depth analysis of one of these agents. Results clearly indicate a frank and specific failure of meta-learning, providing validation for Alchemy as a challenging benchmark for meta-RL. Concurrent with this report, we are releasing Alchemy as public resource, together with a suite of analysis tools and sample agent trajectories.