Sheng Lu

Shan Chen, Yingya Li, Sheng Lu et al. · harvard

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of LLMs such as the ChatGPT family of models (GPT-3.5s, GPT-4) in biomedical tasks beyond question-answering. Because no patient data can be passed to the OpenAI API public interface, we evaluated model performance with over 10000 samples as proxies for two fundamental tasks in the clinical domain - classification and reasoning. The first task is classifying whether statements of clinical and policy recommendations in scientific literature constitute health advice. The second task is causal relation detection from the biomedical literature. We compared LLMs with simpler models, such as bag-of-words (BoW) with logistic regression, and fine-tuned BioBERT models. Despite the excitement around viral ChatGPT, we found that fine-tuning for two fundamental NLP tasks remained the best strategy. The simple BoW model performed on par with the most complex LLM prompting. Prompt engineering required significant investment.

Sheng Lu, Irina Bigoulaeva, Rachneet Sachdeva et al.

Large language models, comprising billions of parameters and pre-trained on extensive web-scale corpora, have been claimed to acquire certain capabilities without having been specifically trained on them. These capabilities, referred to as "emergent abilities," have been a driving force in discussions regarding the potentials and risks of language models. A key challenge in evaluating emergent abilities is that they are confounded by model competencies that arise through alternative prompting techniques, including in-context learning, which is the ability of models to complete a task based on a few examples. We present a novel theory that explains emergent abilities, taking into account their potential confounding factors, and rigorously substantiate this theory through over 1000 experiments. Our findings suggest that purported emergent abilities are not truly emergent, but result from a combination of in-context learning, model memory, and linguistic knowledge. Our work is a foundational step in explaining language model performance, providing a template for their efficient use and clarifying the paradox of their ability to excel in some instances while faltering in others. Thus, we demonstrate that their capabilities should not be overestimated.

Sheng Lu, Shan Chen, Yingya Li et al. · harvard

In-context learning (ICL) is a new learning paradigm that has gained popularity along with the development of large language models. In this work, we adapt a recently proposed hardness metric, pointwise $\mathcal{V}$-usable information (PVI), to an in-context version (in-context PVI). Compared to the original PVI, in-context PVI is more efficient in that it requires only a few exemplars and does not require fine-tuning. We conducted a comprehensive empirical analysis to evaluate the reliability of in-context PVI. Our findings indicate that in-context PVI estimates exhibit similar characteristics to the original PVI. Specific to the in-context setting, we show that in-context PVI estimates remain consistent across different exemplar selections and numbers of shots. The variance of in-context PVI estimates across different exemplar selections is insignificant, which suggests that in-context PVI are stable. Furthermore, we demonstrate how in-context PVI can be employed to identify challenging instances. Our work highlights the potential of in-context PVI and provides new insights into the capabilities of ICL.

Sheng Lu, Hendrik Schuff, Iryna Gurevych

In-context learning (ICL) has become one of the most popular learning paradigms. While there is a growing body of literature focusing on prompt engineering, there is a lack of systematic analysis comparing the effects of prompts across different models and tasks. To address this gap, we present a comprehensive prompt analysis based on the sensitivity of a function. Our analysis reveals that sensitivity is an unsupervised proxy for model performance, as it exhibits a strong negative correlation with accuracy. We use gradient-based saliency scores to empirically demonstrate how different prompts affect the relevance of input tokens to the output, resulting in different levels of sensitivity. Furthermore, we introduce sensitivity-aware decoding which incorporates sensitivity estimation as a penalty term in the standard greedy decoding. We show that this approach is particularly helpful when information in the input is scarce. Our work provides a fresh perspective on the analysis of prompts, and contributes to a better understanding of the mechanism of ICL.

Ilia Kuznetsov, Osama Mohammed Afzal, Koen Dercksen et al.

The number of scientific articles produced every year is growing rapidly. Providing quality control over them is crucial for scientists and, ultimately, for the public good. In modern science, this process is largely delegated to peer review -- a distributed procedure in which each submission is evaluated by several independent experts in the field. Peer review is widely used, yet it is hard, time-consuming, and prone to error. Since the artifacts involved in peer review -- manuscripts, reviews, discussions -- are largely text-based, Natural Language Processing has great potential to improve reviewing. As the emergence of large language models (LLMs) has enabled NLP assistance for many new tasks, the discussion on machine-assisted peer review is picking up the pace. Yet, where exactly is help needed, where can NLP help, and where should it stand aside? The goal of our paper is to provide a foundation for the future efforts in NLP for peer-reviewing assistance. We discuss peer review as a general process, exemplified by reviewing at AI conferences. We detail each step of the process from manuscript submission to camera-ready revision, and discuss the associated challenges and opportunities for NLP assistance, illustrated by existing work. We then turn to the big challenges in NLP for peer review as a whole, including data acquisition and licensing, operationalization and experimentation, and ethical issues. To help consolidate community efforts, we create a companion repository that aggregates key datasets pertaining to peer review. Finally, we issue a detailed call for action for the scientific community, NLP and AI researchers, policymakers, and funding bodies to help bring the research in NLP for peer review forward. We hope that our work will help set the agenda for research in machine-assisted scientific quality control in the age of AI, within the NLP community and beyond.

Lehan He, Zeren Chen, Zhelun Shi et al.

The success of Direct Preference Optimization (DPO) in mitigating hallucinations in Vision Language Models (VLMs) critically hinges on the true reward gaps within preference pairs. However, current methods, typically relying on ranking or rewriting strategies, often struggle to optimize these reward gaps in a systematic way during data curation. A core difficulty lies in precisely characterizing and strategically manipulating the overall reward gap configuration, that is, the deliberate design of how to shape these reward gaps within each preference pair across the data. To address this, we introduce Topic-level Preference Rewriting(TPR), a novel framework designed for the systematic optimization of reward gap configuration. Through selectively replacing semantic topics within VLM responses with model's own resampled candidates for targeted rewriting, TPR can provide topic-level control over fine-grained semantic details. This precise control enables advanced data curation strategies, such as progressively adjusting the difficulty of rejected responses, thereby sculpting an effective reward gap configuration that guides the model to overcome challenging hallucinations. Comprehensive experiments demonstrate TPR achieves state-of-the-art performance on multiple hallucination benchmarks, outperforming previous methods by an average of 20%. Notably, it significantly reduces hallucinations by up to 93% on ObjectHal-Bench, and also exhibits superior data efficiency towards robust and cost-effective VLM alignment.