Rui Sheng

Yanjie Zhang, Yafei Li, Rui Sheng et al.

Despite the success of Vision-Language Models (VLMs), misleading charts remain a significant challenge due to their deceptive visual structures and distorted data representations. We present ChartCynics, an agentic dual-path framework designed to unmask visual deception via a "skeptical" reasoning paradigm. Unlike holistic models, ChartCynics decouples perception from verification: a Diagnostic Vision Path captures structural anomalies (e.g., inverted axes) through strategic ROI cropping, while an OCR-Driven Data Path ensures numerical grounding. To resolve cross-modal conflicts, we introduce an Agentic Summarizer optimized via a two-stage protocol: Oracle-Informed SFT for reasoning distillation and Deception-Aware GRPO for adversarial alignment. This pipeline effectively penalizes visual traps and enforces logical consistency. Evaluations on two benchmarks show that ChartCynics achieves 74.43% and 64.55% accuracy, providing an absolute performance boost of ~29% over the Qwen3-VL-8B backbone, outperforming state-of-the-art proprietary models. Our results demonstrate that specialized agentic workflows can grant smaller open-source models superior robustness, establishing a new foundation for trustworthy chart interpretation.

Peng Kuai, Yukun Yang, Shaolun Ruan et al.

Rare disease diagnosis is inherently challenging due to heterogeneous symptoms, limited clinical familiarity, and fragmented evidence across specialties. Recent large language model (LLM)-based agentic systems have shown promise by simulating multidisciplinary team discussions to generate and evaluate diagnostic hypotheses. However, fully automated diagnosis remains unrealistic, and existing human-in-the-loop approaches provide limited support for effective clinician-agent collaboration. In practice, clinicians are often presented with final diagnostic outputs and lengthy, unstructured agent discussion logs, making it difficult to inspect reasoning, intervene in a timely manner, or guide agent deliberation effectively. To address these challenges, we developed MDTRoom, an interactive system that transforms multi-agent discussions from linear transcripts into a structured, inspectable workspace. The system externalizes patient data, evidence provenance, hypothesis evolution, and inter-agent conflicts as interconnected visual objects, enabling clinicians to efficiently examine, intervene in, and guide agent reasoning. Our evaluation demonstrates the effectiveness of MDTRoom in supporting clinician-agent collaboration.

Zixin Chen, Peng Liu, Rui Sheng et al.

Language agents are increasingly deployed in complex professional workflows, with tutoring emerging as a particularly high-stakes capability that remains largely unmeasured in existing benchmarks. Effective tutor agents require more than producing correct answers or executing accurate tool calls: a robust tutor must diagnose learner state, adapt support over time, make pedagogically justified decisions grounded in educational evidence, and execute interventions within realistic learning-management systems. We introduce EduAgentBench, a source-grounded benchmark for holistically evaluating tutor agents across the full scope of teaching work. It contains 150 quality-controlled tasks across three capability surfaces: professional pedagogical judgment, situated multi-turn tutoring, and Canvas-style teaching workflow completion. Tasks are constructed through a pedagogical-insight-driven pipeline and evaluated with complementary verification signals and human review. Across a comprehensive evaluation of frontier models, our findings reveal that current models are generally capable of bounded pedagogical judgment, but still fall short of professional teaching standards in situated tutoring and autonomous teaching-workflow execution. To our knowledge, EduAgentBench is the first theory-grounded and realistic benchmark for evaluating the holistic teaching capability of tutor agents, providing a measurement foundation for developing future tutor agents that can support realistic teaching work.

Xingbo Wang, Samantha L. Huey, Rui Sheng et al.

The explosion of scientific literature has made the efficient and accurate extraction of structured data a critical component for advancing scientific knowledge and supporting evidence-based decision-making. However, existing tools often struggle to extract and structure multimodal, varied, and inconsistent information across documents into standardized formats. We introduce SciDaSynth, a novel interactive system powered by large language models (LLMs) that automatically generates structured data tables according to users' queries by integrating information from diverse sources, including text, tables, and figures. Furthermore, SciDaSynth supports efficient table data validation and refinement, featuring multi-faceted visual summaries and semantic grouping capabilities to resolve cross-document data inconsistencies. A within-subjects study with nutrition and NLP researchers demonstrates SciDaSynth's effectiveness in producing high-quality structured data more efficiently than baseline methods. We discuss design implications for human-AI collaborative systems supporting data extraction tasks. The system code is available at https://github.com/xingbow/SciDaEx

Hanxiang Chao, Yihan Bai, Rui Sheng et al.

Large Language Model (LLM) agents are increasingly expected to maintain coherent, long-term personalized memory, yet current benchmarks primarily measure static fact retrieval, overlooking the ability to revise stored beliefs when new evidence emerges. We identify a critical and underexplored failure mode, Implicit Conflict: a later observation invalidates an earlier memory without explicit negation, requiring contextual inference and commonsense reasoning to detect. To rigorously evaluate this capability, we introduce STALE, a benchmark of 400 expert-validated conflict scenarios (1,200 evaluation queries across three probing dimensions) spanning over 100 everyday topics with contexts up to 150K tokens. We propose a three-dimensional probing framework that tests State Resolution (detecting that a prior belief is outdated), Premise Resistance (rejecting queries that falsely presuppose a stale state), and Implicit Policy Adaptation (proactively applying updated states in downstream behavior). A systematic evaluation of frontier LLMs and specialized memory frameworks reveals a pervasive gap between retrieving updated evidence and acting on it, with even the best evaluated model achieving only 55.2% overall accuracy. Models often accept outdated assumptions embedded in a user's query, and they struggle to recognize when a change in one aspect of the user's state should invalidate related memories. To establish an initial baseline for state-aware memory, we further present CUPMem, a prototype that strengthens write-time revision through structured state consolidation and propagation-aware search, suggesting that explicit state adjudication is a promising direction for robust agentic memory.

Qipeng Wang, Rui Sheng, Yafei Li et al.

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios. Specifically, current LLMs suffer from three critical limitations: (1) generating hallucinated medical content due to weak grounding in verified knowledge, (2) asking redundant or inefficient questions rather than discriminative ones that hinder diagnostic progress, and (3) losing coherence over multi-turn dialogues, leading to contradictory or inconsistent conclusions. To address these challenges, we propose MedKGI, a diagnostic framework grounded in clinical practices. MedKGI integrates a medical knowledge graph (KG) to constrain reasoning to validated medical ontologies, selects questions based on information gain to maximize diagnostic efficiency, and adopts an OSCE-format structured state to maintain consistent evidence tracking across turns. Experiments on clinical benchmarks show that MedKGI outperforms strong LLM baselines in both diagnostic accuracy and inquiry efficiency, improving dialogue efficiency by 30% on average while maintaining state-of-the-art accuracy.

Shuo Yan, Xiaolin Wen, Shaolun Ruan et al.

Large Language Model (LLM)-based agentic systems have shown growing promise in tackling complex, multi-step tasks through autonomous planning, reasoning, and interaction with external environments. However, the stochastic nature of LLM generation introduces intrinsic behavioral inconsistency: the same agent may succeed in one execution but fail in another under identical inputs. Diagnosing such inconsistencies remains a major challenge for developers, as agent execution logs are often lengthy, unstructured, and difficult to compare across runs. Existing debugging and evaluation tools primarily focus on inspecting single executions, offering limited support for understanding how and why agent behaviors diverge across repeated runs. To address this challenge, we introduce InconLens, a visual analytics system designed to support interactive diagnosis of LLM-based agentic systems with a particular focus on cross-run behavioral analysis. InconLens introduces information nodes as an intermediate abstraction that captures canonical informational milestones shared across executions, enabling semantic alignment and inspection of agent reasoning trajectories across multiple runs. We demonstrate the effectiveness of InconLens through a detailed case study and further validate its usability and analytical value via expert interviews. Our results show that InconLens enables developers to more efficiently identify divergence points, uncover latent failure modes, and gain actionable insights into improving the reliability and stability of agentic systems.

Yurui Xiang, Xingyi Mao, Rui Sheng et al.

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is essential for assessing whether diagnostic reasoning is reliable and clinically grounded. However, debugging medical LLMs remains difficult. First, developers often lack sufficient medical domain expertise to interpret model errors in clinically meaningful terms. Second, models can fail across a large and diverse set of instances involving different input types, tasks, and reasoning steps, making it challenging for developers to prioritize which errors deserve focused inspection. Third, developers struggle to identify recurring error patterns across cases, as existing debugging practices are largely instance-centric and rely on manual inspection of isolated failures. To address these challenges, we present VeriLLMed, a visual analytics system that integrates external biomedical knowledge to audit and debug medical LLM diagnostic reasoning. VeriLLMed transforms model outputs into comparable reasoning paths, constructs knowledge graph-grounded reference paths, and identifies three recurring classes of diagnosis errors: relation errors, branch errors, and missing errors. Case studies and expert evaluation demonstrate that VeriLLMed helps developers identify clinically implausible reasoning and generate actionable insights that can inform the improvement of medical LLMs.

Zixin Chen, Sicheng Song, Kashun Shum et al.

Misleading visualizations, which manipulate chart representations to support specific claims, can distort perception and lead to incorrect conclusions. Despite decades of research, they remain a widespread issue, posing risks to public understanding and raising safety concerns for AI systems involved in data-driven communication. While recent multimodal large language models (MLLMs) show strong chart comprehension abilities, their capacity to detect and interpret misleading charts remains unexplored. We introduce Misleading ChartQA benchmark, a large-scale multimodal dataset designed to evaluate MLLMs on misleading chart reasoning. It contains 3,026 curated examples spanning 21 misleader types and 10 chart types, each with standardized chart code, CSV data, multiple-choice questions, and labeled explanations, validated through iterative MLLM checks and expert human review. We benchmark 24 state-of-the-art MLLMs, analyze their performance across misleader types and chart formats, and propose a novel region-aware reasoning pipeline that enhances model accuracy. Our work lays the foundation for developing MLLMs that are robust, trustworthy, and aligned with the demands of responsible visual communication.

Yifang Wang, Rui Sheng, Erzhuo Shao et al.

Large language models (LLMs) are transforming scientific workflows, not only through their generative capabilities but also through their emerging ability to use tools, reason about data, and coordinate complex analytical tasks. Yet in most human-AI collaborations, the primary outputs, figures, are still treated as static visual summaries: once rendered, they are handled by both humans and multimodal LLMs as images to be re-interpreted from pixels or captions. The emergent capabilities of LLMs open an opportunity to fundamentally rethink this paradigm. In this paper, we introduce the concept of LLM-native figures: data-driven artifacts that are simultaneously human-legible and machine-addressable. Unlike traditional plots, each artifact embeds complete provenance: the data subset, analytical operations and code, and visualization specification used to generate it. As a result, an LLM can "see through" the figure--tracing selections back to their sources, generating code to extend analyses, and orchestrating new visualizations through natural-language instructions or direct manipulation. We implement this concept through a hybrid language-visual interface that integrates LLM agents with a bidirectional mapping between figures and underlying data. Using the science of science domain as a testbed, we demonstrate that LLM-native figures can accelerate discovery, improve reproducibility, and make reasoning transparent across agents and users. More broadly, this work establishes a general framework for embedding provenance, interactivity, and explainability into the artifacts of modern research, redefining the figure not as an end product, but as an interface for discovery. For more details, please refer to the demo video available at www.llm-native-figure.com.