Yixian Chen

Hongqiu Wang, Yixian Chen, Wu Chen et al.

Ultra-Wide-Field Scanning Laser Ophthalmoscopy (UWF-SLO) images capture high-resolution views of the retina with typically 200 spanning degrees. Accurate segmentation of vessels in UWF-SLO images is essential for detecting and diagnosing fundus disease. Recent studies have revealed that the selective State Space Model (SSM) in Mamba performs well in modeling long-range dependencies, which is crucial for capturing the continuity of elongated vessel structures. Inspired by this, we propose the first Serpentine Mamba (Serp-Mamba) network to address this challenging task. Specifically, we recognize the intricate, varied, and delicate nature of the tubular structure of vessels. Furthermore, the high-resolution of UWF-SLO images exacerbates the imbalance between the vessel and background categories. Based on the above observations, we first devise a Serpentine Interwoven Adaptive (SIA) scan mechanism, which scans UWF-SLO images along curved vessel structures in a snake-like crawling manner. This approach, consistent with vascular texture transformations, ensures the effective and continuous capture of curved vascular structure features. Second, we propose an Ambiguity-Driven Dual Recalibration (ADDR) module to address the category imbalance problem intensified by high-resolution images. Our ADDR module delineates pixels by two learnable thresholds and refines ambiguous pixels through a dual-driven strategy, thereby accurately distinguishing vessels and background regions. Experiment results on three datasets demonstrate the superior performance of our Serp-Mamba on high-resolution vessel segmentation. We also conduct a series of ablation studies to verify the impact of our designs. Our code shall be released upon publication of this work.

Zheqing Li, Yiying Yang, Jiping Lang et al.

Large Language Models (LLMs) have demonstrated considerable potential in general practice. However, existing benchmarks and evaluation frameworks primarily depend on exam-style or simplified question-answer formats, lacking a competency-based structure aligned with the real-world clinical responsibilities encountered in general practice. Consequently, the extent to which LLMs can reliably fulfill the duties of general practitioners (GPs) remains uncertain. In this work, we propose a novel evaluation framework to assess the capability of LLMs to function as GPs. Based on this framework, we introduce a general practice benchmark (GPBench), whose data are meticulously annotated by domain experts in accordance with routine clinical practice standards. We evaluate ten state-of-the-art LLMs and analyze their competencies. Our findings indicate that current LLMs are not yet ready for deployment in such settings without human oversight, and further optimization specifically tailored to the daily responsibilities of GPs is essential.

Guilong Li, Yixian Chen, Qionghua Liao et al.

Travelers may travel to locations they have never visited, which we call potential destinations of them. Especially under a very limited observation, travelers tend to show random movement patterns and usually have a large number of potential destinations, which make them difficult to handle for mobility prediction (e.g., destination prediction). In this paper, we develop a new knowledge graph-based framework (PDPFKG) for potential destination discovery of low predictability travelers by considering trip association relationships between them. We first construct a trip knowledge graph (TKG) to model the trip scenario by entities (e.g., travelers, destinations and time information) and their relationships, in which we introduce the concept of private relationship for complexity reduction. Then a modified knowledge graph embedding algorithm is implemented to optimize the overall graph representation. Based on the trip knowledge graph embedding model (TKGEM), the possible ranking of individuals' unobserved destinations to be chosen in the future can be obtained by calculating triples' distance. Empirically. PDPFKG is tested using an anonymous vehicular dataset from 138 intersections equipped with video-based vehicle detection systems in Xuancheng city, China. The results show that (i) the proposed method significantly outperforms baseline methods, and (ii) the results show strong consistency with traveler behavior in choosing potential destinations. Finally, we provide a comprehensive discussion of the innovative points of the methodology.

Stefano Giovanni Rizzo, Linsey Pang, Yixian Chen et al.

A new method for outlier detection and generation is introduced by lifting data into the space of probability distributions which are not analytically expressible, but from which samples can be drawn using a neural generator. Given a mixture of unknown latent inlier and outlier distributions, a Wasserstein double autoencoder is used to both detect and generate inliers and outliers. The proposed method, named WALDO (Wasserstein Autoencoder for Learning the Distribution of Outliers), is evaluated on classical data sets including MNIST, CIFAR10 and KDD99 for detection accuracy and robustness. We give an example of outlier detection on a real retail sales data set and an example of outlier generation for simulating intrusion attacks. However we foresee many application scenarios where WALDO can be used. To the best of our knowledge this is the first work that studies both outlier detection and generation together.

Xinyu Chen, Yixian Chen, Nicolas Saunier et al.

Missing value problem in spatiotemporal traffic data has long been a challenging topic, in particular for large-scale and high-dimensional data with complex missing mechanisms and diverse degrees of missingness. Recent studies based on tensor nuclear norm have demonstrated the superiority of tensor learning in imputation tasks by effectively characterizing the complex correlations/dependencies in spatiotemporal data. However, despite the promising results, these approaches do not scale well to large data tensors. In this paper, we focus on addressing the missing data imputation problem for large-scale spatiotemporal traffic data. To achieve both high accuracy and efficiency, we develop a scalable tensor learning model -- Low-Tubal-Rank Smoothing Tensor Completion (LSTC-Tubal) -- based on the existing framework of Low-Rank Tensor Completion, which is well-suited for spatiotemporal traffic data that is characterized by multidimensional structure of location$\times$ time of day $\times$ day. In particular, the proposed LSTC-Tubal model involves a scalable tensor nuclear norm minimization scheme by integrating linear unitary transformation. Therefore, tensor nuclear norm minimization can be solved by singular value thresholding on the transformed matrix of each day while the day-to-day correlation can be effectively preserved by the unitary transform matrix. We compare LSTC-Tubal with state-of-the-art baseline models, and find that LSTC-Tubal can achieve competitive accuracy with a significantly lower computational cost. In addition, the LSTC-Tubal will also benefit other tasks in modeling large-scale spatiotemporal traffic data, such as network-level traffic forecasting.