Ruimin Feng

Qing Wu, Ruimin Feng, Hongjiang Wei et al.

In the present work, we propose a Self-supervised COordinate Projection nEtwork (SCOPE) to reconstruct the artifacts-free CT image from a single SV sinogram by solving the inverse tomography imaging problem. Compared with recent related works that solve similar problems using implicit neural representation network (INR), our essential contribution is an effective and simple re-projection strategy that pushes the tomography image reconstruction quality over supervised deep learning CT reconstruction works. The proposed strategy is inspired by the simple relationship between linear algebra and inverse problems. To solve the under-determined linear equation system, we first introduce INR to constrain the solution space via image continuity prior and achieve a rough solution. And secondly, we propose to generate a dense view sinogram that improves the rank of the linear equation system and produces a more stable CT image solution space. Our experiment results demonstrate that the re-projection strategy significantly improves the image reconstruction quality (+3 dB for PSNR at least). Besides, we integrate the recent hash encoding into our SCOPE model, which greatly accelerates the model training. Finally, we evaluate SCOPE in parallel and fan X-ray beam SVCT reconstruction tasks. Experimental results indicate that the proposed SCOPE model outperforms two latest INR-based methods and two well-popular supervised DL methods quantitatively and qualitatively.

Jie Feng, Ruimin Feng, Qing Wu et al.

Supervised Deep-Learning (DL)-based reconstruction algorithms have shown state-of-the-art results for highly-undersampled dynamic Magnetic Resonance Imaging (MRI) reconstruction. However, the requirement of excessive high-quality ground-truth data hinders their applications due to the generalization problem. Recently, Implicit Neural Representation (INR) has appeared as a powerful DL-based tool for solving the inverse problem by characterizing the attributes of a signal as a continuous function of corresponding coordinates in an unsupervised manner. In this work, we proposed an INR-based method to improve dynamic MRI reconstruction from highly undersampled k-space data, which only takes spatiotemporal coordinates as inputs. Specifically, the proposed INR represents the dynamic MRI images as an implicit function and encodes them into neural networks. The weights of the network are learned from sparsely-acquired (k, t)-space data itself only, without external training datasets or prior images. Benefiting from the strong implicit continuity regularization of INR together with explicit regularization for low-rankness and sparsity, our proposed method outperforms the compared scan-specific methods at various acceleration factors. E.g., experiments on retrospective cardiac cine datasets show an improvement of 5.5 ~ 7.1 dB in PSNR for extremely high accelerations (up to 41.6-fold). The high-quality and inner continuity of the images provided by INR has great potential to further improve the spatiotemporal resolution of dynamic MRI, without the need of any training data.

Lixuan Chen, Xuanyu Tian, Jiangjie Wu et al.

Magnetic Resonance Imaging (MRI) stands as a powerful modality in clinical diagnosis. However, it is known that MRI faces challenges such as long acquisition time and vulnerability to motion-induced artifacts. Despite the success of many existing motion correction algorithms, there has been limited research focused on correcting motion artifacts on the estimated coil sensitivity maps for fast MRI reconstruction. Existing methods might suffer from severe performance degradation due to error propagation resulting from the inaccurate coil sensitivity maps estimation. In this work, we propose to jointly estimate the motion parameters and coil sensitivity maps for under-sampled MRI reconstruction, referred to as JSMoCo. However, joint estimation of motion parameters and coil sensitivities results in a highly ill-posed inverse problem due to an increased number of unknowns. To address this, we introduce score-based diffusion models as powerful priors and leverage the MRI physical principles to efficiently constrain the solution space for this optimization problem. Specifically, we parameterize the rigid motion as three trainable variables and model coil sensitivity maps as polynomial functions. Leveraging the physical knowledge, we then employ Gibbs sampler for joint estimation, ensuring system consistency between sensitivity maps and desired images, avoiding error propagation from pre-estimated sensitivity maps to the reconstructed images. We conduct comprehensive experiments to evaluate the performance of JSMoCo on the fastMRI dataset. The results show that our method is capable of reconstructing high-quality MRI images from sparsely-sampled k-space data, even affected by motion. It achieves this by accurately estimating both motion parameters and coil sensitivities, effectively mitigating motion-related challenges during MRI reconstruction.

Ruimin Feng, Albert Jang, Xingxin He et al.

Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel REinforcement), combining an implicit neural representation (INR) architecture with a model reinforcement module that incorporates MR physics constraints. The INR component enables informative learning of spatiotemporal correlations to initialize multiparametric quantitative maps, which are then further refined through an unrolled optimization scheme enforcing data consistency. To improve computational efficiency, REFINE-MORE integrates a low-rank adaptation strategy that promotes rapid model convergence. We evaluated REFINE-MORE on accelerated multiparametric quantitative magnetization transfer imaging for simultaneous estimation of free water spin-lattice relaxation, tissue macromolecular proton fraction, and magnetization exchange rate, using both phantom and in vivo brain data. Results: Under 4x and 5x accelerations on in vivo data, REFINE-MORE achieved superior reconstruction quality, demonstrating the lowest normalized root-mean-square error and highest structural similarity index compared to baseline methods and other state-of-the-art model-based and deep learning approaches. Phantom experiments further showed strong agreement with reference values, underscoring the robustness and generalizability of the proposed framework. Additionally, the model adaptation strategy improved reconstruction efficiency by approximately fivefold. Conclusion: REFINE-MORE enables accurate and efficient scan-specific multiparametric qMRI reconstruction, providing a flexible solution for high-dimensional, accelerated qMRI applications.