Li Fang

Fang Li, Yi Nian, Zenan Sun et al.

Graph representation learning (GRL) has emerged as a pivotal field that has contributed significantly to breakthroughs in various fields, including biomedicine. The objective of this survey is to review the latest advancements in GRL methods and their applications in the biomedical field. We also highlight key challenges currently faced by GRL and outline potential directions for future research.

Xinyue Hu, Zenan Sun, Yi Nian et al.

Background: Alzheimer's disease and related dementias (ADRD) ranks as the sixth leading cause of death in the US, underlining the importance of accurate ADRD risk prediction. While recent advancement in ADRD risk prediction have primarily relied on imaging analysis, yet not all patients undergo medical imaging before an ADRD diagnosis. Merging machine learning with claims data can reveal additional risk factors and uncover interconnections among diverse medical codes. Objective: Our goal is to utilize Graph Neural Networks (GNNs) with claims data for ADRD risk prediction. Addressing the lack of human-interpretable reasons behind these predictions, we introduce an innovative method to evaluate relationship importance and its influence on ADRD risk prediction, ensuring comprehensive interpretation. Methods: We employed Variationally Regularized Encoder-decoder Graph Neural Network (VGNN) for estimating ADRD likelihood. We created three scenarios to assess the model's efficiency, using Random Forest and Light Gradient Boost Machine as baselines. We further used our relation importance method to clarify the key relationships for ADRD risk prediction. Results: VGNN surpassed other baseline models by 10% in the area under the receiver operating characteristic. The integration of the GNN model and relation importance interpretation could potentially play an essential role in providing valuable insight into factors that may contribute to or delay ADRD progression. Conclusions: Employing a GNN approach with claims data enhances ADRD risk prediction and provides insights into the impact of interconnected medical code relationships. This methodology not only enables ADRD risk modeling but also shows potential for other image analysis predictions using claims data.

Shaoqing Xu, Fang Li, Peixiang Huang et al.

Accurate multi-view 3D object detection is essential for applications such as autonomous driving. Researchers have consistently aimed to leverage LiDAR's precise spatial information to enhance camera-based detectors through methods like depth supervision and bird-eye-view (BEV) feature distillation. However, existing approaches often face challenges due to the inherent differences between LiDAR and camera data representations. In this paper, we introduce the TiGDistill-BEV, a novel approach that effectively bridges this gap by leveraging the strengths of both sensors. Our method distills knowledge from diverse modalities(e.g., LiDAR) as the teacher model to a camera-based student detector, utilizing the Target Inner-Geometry learning scheme to enhance camera-based BEV detectors through both depth and BEV features by leveraging diverse modalities. Specially, we propose two key modules: an inner-depth supervision module to learn the low-level relative depth relations within objects which equips detectors with a deeper understanding of object-level spatial structures, and an inner-feature BEV distillation module to transfer high-level semantics of different key points within foreground targets. To further alleviate the domain gap, we incorporate both inter-channel and inter-keypoint distillation to model feature similarity. Extensive experiments on the nuScenes benchmark demonstrate that TiGDistill-BEV significantly boosts camera-based only detectors achieving a state-of-the-art with 62.8% NDS and surpassing previous methods by a significant margin. The codes is available at: https://github.com/Public-BOTs/TiGDistill-BEV.git.

Meng Wang, Huafeng Li, Fang Li

The GANs promote an adversarive game to approximate complex and jointed example probability. The networks driven by noise generate fake examples to approximate realistic data distributions. Later the conditional GAN merges prior-conditions as input in order to transfer attribute vectors to the corresponding data. However, the CGAN is not designed to deal with the high dimension conditions since indirect guide of the learning is inefficiency. In this paper, we proposed a network ResGAN to generate fine images in terms of extremely degenerated images. The coarse images aligned to attributes are embedded as the generator inputs and classifier labels. In generative network, a straight path similar to the Resnet is cohered to directly transfer the coarse images to the higher layers. And adversarial training is circularly implemented to prevent degeneration of the generated images. Experimental results of applying the ResGAN to datasets MNIST, CIFAR10/100 and CELEBA show its higher accuracy to the state-of-art GANs.