Vaibhav Gupta

Vaibhav Gupta, Poonam Goel, Usha Agrawal et al.

Introduction: Electrical impedance spectroscopy (EIS) has recently developed as a novel diagnostic device for screening and evaluating cervical dysplasia, prostate cancer, breast cancer and basal cell carcinoma. The current study aimed to validate and evaluate bioimpedance as a diagnostic tool for tobacco-induced oral lesions. Methodology: The study comprised 50 OSCC and OPMD tissue specimens for in-vitro study and 320 subjects for in vivo study. Bioimpedance device prepared and calibrated. EIS measurements were done for the habit and control groups and were compared. Results: The impedance value in the control group was significantly higher compared to the OPMD and OSCC groups. Diagnosis based on BIS measurements has a sensitivity of 95.9% and a specificity of 86.7%. Conclusion: Bioimpedance device can help in decision-making for differentiating OPMD and OSCC cases and their management, especially in primary healthcare settings. Keywords: Impedance, Cancer, Diagnosis, Device, Community

Prakhar Gupta, Vaibhav Gupta

Post-training with reinforcement learning (RL) typically optimizes a single scalar objective and ignores structure in how solutions are produced. We ask whether a scalar hint toward a canonical solver ordering, used only during RL post-training, improves performance even when fine-tuned on randomized solution sequences. On Sudoku, we train a Transformer with standard fine-tuning on randomized solving orders, then post-train it with Group Relative Policy Optimization (GRPO) with two rewards: cell accuracy and an ordering reward that increases when the model's emission order aligns with the solver order. To compare signals cleanly, we combine them via fixed mixtures and use a simple bootstrapped scaling to equalize component magnitudes at initialization. Mixed rewards generally outperform cell-only optimization--the best mixture yields substantially higher test accuracy than the fine-tuned-only model trained on random-order and approaches the fine-tuned-only model trained on solver-order sequences in accuracy. These results suggest that coarse ordering signals can steer RL post-training toward solver-order trajectories without modifying supervised data or architecture.