Xiao Li

Praneeth Chakravarthula, Jipeng Sun, Xiao Li et al.

Today's commodity camera systems rely on compound optics to map light originating from the scene to positions on the sensor where it gets recorded as an image. To record images without optical aberrations, i.e., deviations from Gauss' linear model of optics, typical lens systems introduce increasingly complex stacks of optical elements which are responsible for the height of existing commodity cameras. In this work, we investigate flat nanophotonic computational cameras as an alternative that employs an array of skewed lenslets and a learned reconstruction approach. The optical array is embedded on a metasurface that, at 700~nm height, is flat and sits on the sensor cover glass at 2.5~mm focal distance from the sensor. To tackle the highly chromatic response of a metasurface and design the array over the entire sensor, we propose a differentiable optimization method that continuously samples over the visible spectrum and factorizes the optical modulation for different incident fields into individual lenses. We reconstruct a megapixel image from our flat imager with a learned probabilistic reconstruction method that employs a generative diffusion model to sample an implicit prior. To tackle scene-dependent aberrations in broadband, we propose a method for acquiring paired captured training data in varying illumination conditions. We assess the proposed flat camera design in simulation and with an experimental prototype, validating that the method is capable of recovering images from diverse scenes in broadband with a single nanophotonic layer.

Yiran Wang, Li Xiao

It has been shown that traditional deep learning methods for electronic microscopy segmentation usually suffer from low transferability when samples and annotations are limited, while large-scale vision foundation models are more robust when transferring between different domains but facing sub-optimal improvement under fine-tuning. In this work, we present a new few-shot domain adaptation framework SAMDA, which combines the Segment Anything Model(SAM) with nnUNet in the embedding space to achieve high transferability and accuracy. Specifically, we choose the Unet-based network as the "expert" component to learn segmentation features efficiently and design a SAM-based adaptation module as the "generic" component for domain transfer. By amalgamating the "generic" and "expert" components, we mitigate the modality imbalance in the complex pre-training knowledge inherent to large-scale Vision Foundation models and the challenge of transferability inherent to traditional neural networks. The effectiveness of our model is evaluated on two electron microscopic image datasets with different modalities for mitochondria segmentation, which improves the dice coefficient on the target domain by 6.7%. Also, the SAM-based adaptor performs significantly better with only a single annotated image than the 10-shot domain adaptation on nnUNet. We further verify our model on four MRI datasets from different sources to prove its generalization ability.