Xue Wu

Chenchu Xu, Meng Li, Xue Wu

The accurate segmentation of Coronary Computed Tomography Angiography (CCTA) images holds substantial clinical value for the early detection and treatment of Coronary Heart Disease (CHD). The Transformer, utilizing a self-attention mechanism, has demonstrated commendable performance in the realm of medical image processing. However, challenges persist in coronary segmentation tasks due to (1) the damage to target local structures caused by fixed-size image patch embedding, and (2) the critical role of both global and local features in medical image segmentation tasks.To address these challenges, we propose a deep learning framework, TransCC, that effectively amalgamates the Transformer and convolutional neural networks for CCTA segmentation. Firstly, we introduce a Feature Interaction Extraction (FIE) module designed to capture the characteristics of image patches, thereby circumventing the loss of semantic information inherent in the original method. Secondly, we devise a Multilayer Enhanced Perceptron (MEP) to augment attention to local information within spatial dimensions, serving as a complement to the self-attention mechanism. Experimental results indicate that TransCC outperforms existing methods in segmentation performance, boasting an average Dice coefficient of 0.730 and an average Intersection over Union (IoU) of 0.582. These results underscore the effectiveness of TransCC in CCTA image segmentation.

Xue Wu, Kostas Tsioutsiouliklis

Large Language Models (LLMs) have demonstrated remarkable capabilities in natural language understanding and generation. However, they often struggle with complex reasoning tasks and are prone to hallucination. Recent research has shown promising results in leveraging knowledge graphs (KGs) to enhance LLM performance. KGs provide a structured representation of entities and their relationships, offering a rich source of information that can enhance the reasoning capabilities of LLMs. For this work, we have developed different techniques that tightly integrate KG structures and semantics into LLM representations. Our results show that we are able to significantly improve the performance of LLMs in complex reasoning scenarios, and ground the reasoning process with KGs. We are the first to represent KGs with programming language and fine-tune pretrained LLMs with KGs. This integration facilitates more accurate and interpretable reasoning processes, paving the way for more advanced reasoning capabilities of LLMs.